UNASSIGNED:通过分析全国注册数据库中的数据,调查中国系统性血管炎患者的临床特征,中国系统性血管炎注册中心(CRSV)。
未经评估:人口统计数据,临床表现,图像和实验室测试结果,疾病活动评估,治疗,以及确诊为系统性血管炎的患者的结局,包括Takayasu动脉炎(TAK),ANCA相关性血管炎(AAV),Behcet综合征(BD),结节性血管炎(PAN),和未分类的系统性血管炎(USV),自2013年7月以来在CRSV中收集。检索并分析了2013年7月和2020年2月28日的数据。
未经授权:截至2020年2月,共有3852名患者在CRSV中登记。北京协和医院,登记了1348名患者,包括730名TAK患者,343患有Behcet病(BD),191与AAV,53与USV,31与PAN。在PAN中发现了更多的男性患者(64.5%),BD(59.8%),和AAV(52.4%),而TAK在女性患者中更为普遍(85.9%)。在TAK中,疾病诊断的平均年龄为29.6岁,33.2inBD,在PAN中28.6,39.4在USV中,和48.1在AAV中。在诊断为TAK和AAV的年龄之间发现了显着差异。性别比较显示,男性AAV患者的诊断年龄大于女性患者。高血压(57.3%)和卒中(17.5%)在男性TAK患者中更为常见,血管受累(27.3%)在男性BD患者中更为常见,而男性AAV患者的神经系统受累(29.0%)比女性更常见。
UNASSIGNED:该注册表在中国是第一个,提供了有关中国系统性血管炎患者临床特征的丰富信息。不同类别的系统性血管炎之间的临床表现存在显着差异。
UNASSIGNED: To investigate the clinical characteristics of patients with systemic vasculitis in
China by analyzing the data from a nationwide registry database, the Chinese Registry for Systemic Vasculitis (CRSV).
UNASSIGNED: The demographic data, clinical presentations, image and laboratory test results, disease activity assessment, treatment, and outcome of patients enrolled with the confirmed diagnosis of systemic vasculitis, including Takayasu\'s arteritis (TAK), ANCA-associated vasculitis (AAV), Behcet\'s syndrome (BD), Polyangitis nodosa (PAN), and unclassified systemic vasculitis (USV), were collected since July 2013 in the CRSV. The data during July 2013 and February 28 of 2020 were retrieved and analyzed.
UNASSIGNED: Up to February 2020, 3852 patients in total were registered in the CRSV. In Peking Union Medical College Hospital (PUMCH), 1348 patients were registered, including 730 patients with TAK, 343 with Behcet\'s disease (BD), 191 with AAV, 53 with USV, and 31 with PAN. More male patients were found in PAN (64.5%), BD (59.8%), and AAV (52.4%), while TAK was more prevalent in female patients (85.9%). The average age at disease diagnosis was 29.6 in TAK, 33.2 in BD, 28.6 in PAN, 39.4 in USV, and 48.1 in AAV. A significant difference was found between age at diagnosis of TAK and AAV. Gender comparisons revealed that the age at diagnosis of male patients with AAV was older than female patients. Hypertension (57.3%) and stroke (17.5%) were found to be more common in male patients with TAK, vascular involvement (27.3%) was found to be more common in male patients with BD, while neurological involvement (29.0%) was found to be more common in male patients with AAV than in females.
UNASSIGNED: This registry is the first in
China and provides rich information about the clinical characteristics of Chinese patients with systemic vasculitis. There are significant differences in clinical presentations between different categories of systemic vasculitis.