本研究旨在调查杭州市小儿肠套叠的季节性以及气象因素与小儿肠套叠的关系。以及旨在比较性别和疾病类型的差异。
2014年1月至2021年12月在浙江大学儿童医院进行了为期8年的回顾性研究,杭州,中国。
这是杭州某大型儿童医院肠套叠病例的单中心回顾性研究。
本研究共有17674例肠套叠患者。
使用Spearman相关分析和Poisson回归分析来确定每周肠套叠病例与气象因素之间的关联。通过t检验和可视化证明了小儿肠套叠的季节性。
1月,五月和十二月,肠套叠患者相对较多。2月,肠套叠患者人数出现低谷。Spearman相关分析和Poisson回归分析均证明每周肠套叠病例与体温有显著相关性(λ=-0.205,p<0.01;β=-0.080,p<0.01),触感状温度(λ=-0.214,p<0.01;β=-0.012,p<0.01),露水(λ=-0.249,p<0.01;β=0.095,p<0.01),湿度(λ=-0.230,p<0.01;β=-0.037,p<0.01),降水量(λ=-0.148,p<0.01;β=-0.001,p<0.01),风速(λ=-0.135,p<0.01;β=0.005,p<0.01),能见度(λ=-0.206,p<0.01;β=-0.066,p<0.01),海平面压力(λ=0.171,p<0.01;β=-0.004,p<0.01)和25个动态气象因子中的20个(p<0.05)。这些关联反映了性别差异,但在容易复发的群体中显示出更强的关联。
杭州小儿肠套叠呈季节性趋势。此外,在所有病例中,肠套叠与某些气象因素显著相关。这些发现表明,父母和儿科医生应就季节性变化时间和气候变化时间对儿童肠套叠的发生保持警惕。
This study aimed to investigate the seasonality of paediatric intussusception and the associations between meteorological factors and paediatric intussusception in Hangzhou, as well as aimed to compare the variance in sex and disease type.
An 8-year retrospective study was conducted from January 2014 to December 2021 in the Children\'s Hospital of Zhejiang University, Hangzhou,
China.
This was a single-centre retrospective study review of intussusception cases in a large Children\'s Hospital in Hangzhou.
There were 17 674 patients with intussusception in this study.
A Spearman correlation analysis and Poisson regression analysis were used to determine the association between weekly intussusception cases and meteorological factors. The seasonality of paediatric intussusception was demonstrated via the t-test and visualised.
In January, May and December, there were relatively more intussusception patients. In February, there was a trough in the number of intussusception patients. Both the Spearman correlation analysis and Poisson regression analysis proved that weekly intussusception cases had significant associations with temperature (λ=-0.205, p<0.01; β=-0.080, p<0.01), feels-like temperature (λ=-0.214, p<0.01; β=-0.012, p<0.01), dew (λ=-0.249, p<0.01; β=0.095, p<0.01), humidity (λ=-0.230, p<0.01; β=-0.037, p<0.01), precipitation (λ=-0.148, p<0.01; β=-0.001, p<0.01), windspeed (λ=-0.135, p<0.01; β=0.005, p<0.01), visibility (λ=-0.206, p<0.01; β=-0.066, p<0.01), sea level pressure (λ=0.171, p<0.01; β=-0.004, p<0.01) and a total of 20 of 25 dynamic meteorological factors (p<0.05). These associations reflected gender differences but showed stronger associations in groups that were prone to recurrence.
Paediatric intussusception in Hangzhou showed a seasonal tendency. Additionally, intussusception was significantly associated with certain meteorological factors in all of the cases. These findings suggest that parents and paediatricians should be more vigilant about the occurrence of intussusception in children regarding seasonal change times and climate change times.