UNASSIGNED:探讨来自24小时Holter记录的Poincaré图在区分儿科患者的血管迷走性晕厥(VVS)和体位性心动过速综合征(POTS)中的作用。
未经证实:患有VVS或POTS的儿科患者,2012年1月至2018年12月在北京大学第一医院住院的患者被纳入一项衍生研究.横轴(T),纵轴(L),T/L比,产品T×L,原点与纵轴近端之间的距离(pro-D),在VVS和POTS组之间比较了庞加莱图的纵轴(dis-D)的原点和远端之间的距离,并使用接收器工作特性曲线分析评估了上述图形参数的差异诊断性能。在2019年1月至2020年12月期间住院的儿科患者中进行了验证研究。
未经批准:在学龄儿童中,T,L,T/L,T×L,VVS患者的Dis-D值大于POTS患者;在青少年中,T,T/L,T×L,VVS患者的pro-D值大于POTS患者的pro-D值。使用0.3的T/L临界值来区分这两种疾病,敏感性和特异性分别为91.0%和90.5%,分别,总参与者;91.6%和88.9%,分别,学龄儿童;82.1%和95.7%,分别,为青少年。在验证研究中,T/L截断值为0.3,获得了精度,灵敏度,特异性分别为81.8、87.2和77.6%,分别,在总参与者中;76.5%、82.6%和71.4%,分别,学龄儿童占89.2%、93.8%和85.7%,分别,在青少年中,通过临床诊断验证了VVS与POTS的区别。
UNASSIGNED:庞加莱图的图形参数在儿科患者的VVS和POTS之间显着不同,Poincaré图的T/L可能是帮助区分儿童和青少年VVS与POTS的有用指标。
UNASSIGNED: To explore the role of the Poincaré plot derived from a 24-hour Holter recording in distinguishing vasovagal syncope (VVS) from postural tachycardia syndrome (POTS) in pediatric patients.
UNASSIGNED: Pediatric patients with VVS or POTS, hospitalized in Peking University First Hospital between January 2012 and December 2018, were included in a derivation study. The transverse axis (T), longitudinal axis (L), T/L ratio, product T × L, distance between the origin and the proximal end of the longitudinal axis (pro-D), and distance between the origin and distal end of the longitudinal axis (dis-D) of the Poincaré plot were compared between the VVS and POTS groups, and the differential diagnostic performance of the above-mentioned graphic parameters was evaluated using receiver operating characteristic curve analysis. A validation study was conducted in pediatric patients hospitalized between January 2019 and December 2020.
UNASSIGNED: In school-aged children, the T, L, T/L, T × L, and dis-D values of patients with VVS were greater than those of patients with POTS; in adolescents, the T, T/L, T × L, and pro-D values of patients with VVS were greater than those of patients with POTS. Using a T/L cut-off value of 0.3 to distinguish between the two diseases, the sensitivity and specificity were 91.0 and 90.5%, respectively, for the total participants; 91.6 and 88.9%, respectively, for the school-aged children; and 82.1 and 95.7%, respectively, for the adolescents. In the validation study, a T/L cut-off value of 0.3 yielded an accuracy, sensitivity, and specificity of 81.8, 87.2, and 77.6%, respectively, in the total participants; 76.5, 82.6, and 71.4%, respectively, in the school-aged children; and 89.2, 93.8, and 85.7%, respectively, in the adolescents, in distinguishing VVS from POTS validated by clinical diagnosis.
UNASSIGNED: The graphic parameters of the Poincaré plot are significantly different between VVS and POTS in pediatric patients, and the T/L of the Poincaré plot may be a useful measure to help differentiate VVS from POTS in children and adolescents.