锑是剧毒和关键的水污染物,这需要密切监测。迄今为止,然而,大多数锑检测的分析方法都相当有限,因为它们很复杂,贵,不适合锑的实时监测。在这项研究中,首次开发了一种基于液晶和10聚体聚腺嘌呤寡核苷酸作为特异性识别探针的无标记快速检测锑离子(Sb3)的方法。工作原理是基于寡核苷酸与Sb3+的结合,这削弱了寡核苷酸和阳离子表面活性剂之间的相互作用。因此,该事件引起液晶的平面到垂直取向变化和在交叉极地下的亮到暗光学变化。这种基于液晶的光学传感器在10秒内对Sb3+表现出快速响应,检测范围在20nM和5μM之间,和从10分钟测定时间计算的6.7nM的检测极限。它还显示出对其他金属离子(包括Ag+)的良好选择性,Cd2+,Cu2+,Fe3+,K+,Mg2+,Mn2+,Na+,Pb2+,和Zn2+。此外,该系统可用于检测具有不同pH或离子强度的水溶液中的Sb3+。这个简单的,快,和低成本的基于液晶的传感方法具有高灵敏度和选择性,具有检测自然环境和工业废水中Sb3的潜力。
Antimony is highly toxic and a key water pollutant, which needs to be monitored closely. To date, however, most analytical methods for antimony detection are quite limited because they are complicated, expensive, and not suitable for real-time monitoring of antimony. In this study, a label-free and rapid method for antimony ions (Sb3+) detection is developed based on liquid crystals and a 10-mer poly-adenine
oligonucleotide as a specific recognition probe for the first time. The working principle is based on the binding of the
oligonucleotide to Sb3+, which weakens the interaction between the
oligonucleotide and cationic surfactants. As a result, the event induces a planar-to-homeotropic orientational change of liquid crystals and a bright-to-dark optical change under crossed polars. This liquid crystal-based optical sensor exhibits a rapid response to Sb3+ in 10 s, a detection range between 20 nM and 5 μM, and a detection limit at 6.7 nM calculated from 10-mins assay time. It also shows good selectivity against other metal ions including Ag+, Cd2+, Cu2+, Fe3+, K+, Mg2+, Mn2+, Na+, Pb2+, and Zn2+. Moreover, this system can be used to detect Sb3+ in aqueous solutions with different pH or ionic strengths. This simple, fast, and low-cost liquid crystal-based sensing approach with high sensitivity and selectivity has a high potential for detecting Sb3+ in natural environments and industrial wastewater.