未经评估:严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)的Omicron变种于2022年3月开始流行,直到2022年5月初在上海确认了60多万例病例。中国。Omicron感染的数据在其他国家都有,但是中国人群患者的临床特征,尤其是在上海,仍然缺乏。我们从无症状和轻度疾病患者的子集收集数据,以根据周期阈值的变化了解Omicron感染的年龄和性别差异。
UNASSIGNED:通过病历收集了连续入住上海老年病中心的325名患者的基本信息,患者在住院期间使用鼻拭子样本检测病毒核酸携带。SAS9.4用于数据分析,p值<0.05%被认为具有统计学意义。
未经证实:在325名患者中,58.8%是男性,平均年龄47.2岁,平均住院13.6天。女性患者的平均核酸检测次数为4.7次,高于男性患者(4.1次)。核酸检测(NAD)测试中循环阈值(Ct)变化的斜率的中值为1.4。Logistic回归显示,男性患者Ct变化>1.5的斜率比例略高于女性患者(比值比(OR)=1.06,95%置信区间(CI):0.68-1.66)。年龄<45岁和45-59岁的患者的Ct变化斜率>1.5的比例高于年龄≥60岁的患者。Ct值在感染早期变化较大,在感染后期稳定。
未经证实:在轻度疾病或无症状感染的患者中,CT值很好,及时,和经济有效的方法来反映患者的康复进展。年轻患者和男性患者的Ct变化斜率较陡,这表明疾病恢复更快。
UNASSIGNED: An epidemic of the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in March 2022, and over 600,000 cases were confirmed until early May 2022 in Shanghai,
China. Data on Omicron infections are available in other countries, but the clinical features of patients in the Chinese population, especially in Shanghai, are still lacking. We collected data from a subset of asymptomatic and mildly ill patients to learn about the age and sex disparity of Omicron infection based on changes in cycle threshold values.
UNASSIGNED: The basic information of 325 patients who were consecutively admitted to the Shanghai Geriatrics Center was collected through medical records, and patients were tested for viral nucleic acid carriage using nasal swab samples during hospitalization. SAS 9.4 was used for data analysis, and a p value < 0.05% was considered statistically significant.
UNASSIGNED: Among the 325 included patients, 58.8% were males, with a mean age of 47.2 years and 13.6 days of hospitalization on average. The average number of nucleic acid tests among female patients was 4.7, which was higher than that among male patients (4.1). The median value of the slope for cycle threshold (Ct) changes in the nucleic acid detection (NAD) test was 1.4. Logistic regression indicated that the proportion of slope for Ct changes >1.5 was slightly higher among male patients than among female patients (odds ratio (OR) = 1.06, 95% confidence interval (CI): 0.68-1.66), and patients aged <45 years and 45-59 years had a higher proportion of slope for Ct changes >1.5 than patients aged ≥60 years. Ct values were more variable in the early stages of infection and stabilized in the later stages of infection.
UNASSIGNED: Among patients with mild illness or asymptomatic infection, the Ct value is a good, timely, and cost-effective method to reflect the recovery progress of patients. The slope of Ct changes was steeper among younger patients and male patients, which indicates faster disease recovery.