牛副结核是由鸟分枝杆菌亚种副结核(MAP)引起的慢性传染病。这里,我们进行了系统的文献综述,调查了2022年前中国牛副结核病的分布和相关危险因素.CNKI数据库,VIP,万方,PubMed,和ScienceDirect被用来搜索文章。使用“R”软件的“Meta”软件包的随机效应模型,并选择余弦变换进行速率转换分析。为了揭示导致研究异质性的因素,研究数据用于亚组分析和单因素荟萃回归分析.在1238篇文章中,54符合资格标准。根据从所选文章中获得的数据,我国牛副结核合并阳性率为6.95%。在抽样年份亚组中,2013年以前牛副结核的阳性率为4.94%,低于其他时间段。在采样季节亚组中,秋季牛副结核阳性率最高,为14.60%。此外,在检测方法子群中,牛副结核阳性率最高为7.21%,用ELISA检测。在年龄亚组中,牛12月龄以上的牛副结核阳性率为17.47%,显著高于其他年龄亚组。性别亚组母牛副结核阳性率最高,为11.35%,而在地理区域分组中,华东地区阳性率最高,为8.12%,明显高于其他地区。牛副结核阳性率最高的是奶牛(8.00%),非规模养殖法阳性率最高,为11.03%。评价了不同地理和气候因素对牛副结核病阳性率的影响。总之,我们建议在温暖潮湿的地区重点筛查感染MAP的牛。
Bovine paratuberculosis is a chronic infectious disease caused by Mycobacterium avium subspecies paratuberculosis (MAP). Here, a systematic literature review was conducted to investigate the bovine paratuberculosis distribution and associated risk factors in
China before 2022. The databases CNKI, VIP, WanFang, PubMed, and ScienceDirect were used to search for articles. The random effect model of the \"Meta\" package of \"R\" software was used, and the Arcsine transformation was chosen for the rate conversion analysis. To reveal the factors that led to research heterogeneity, the research data were used for subgroup analysis and univariate meta-regression analysis. Among the 1238 identified articles, 54 met the eligibility criteria. Based on data obtained from the selected articles, the combined positive rate of bovine paratuberculosis was 6.95% in
China. In the sampling year subgroup, the positive rate of bovine paratuberculosis before 2013 was 4.94%, which was lower than in other time periods. In the sampling season subgroup, the highest positive rate of bovine paratuberculosis in cattle was 14.60% in the autumn. Furthermore, in the detection method subgroup, the highest positive rate of bovine paratuberculosis was 7.21%, which was detected by using ELISA. In the age subgroup, the positive rate of bovine paratuberculosis was 17.47% in cattle > 12 months old, significantly higher than other age subgroups. The highest positive rate of bovine paratuberculosis was 11.35% for female cattle in the gender subgroup, while in the geographic region subgroup, the highest positive rate was 8.12% for East
China, which was significantly higher than in other regions. The highest positive rate of bovine paratuberculosis was for dairy cattle (8.00%), and the highest positive rate by rearing method was 11.03% for non-scale farming. The effects of different geographical and climatic factors on the positive rate of bovine paratuberculosis were evaluated. In summary, we recommend focusing on screening cattle infected with MAP in warm and humid areas.