■机器人辅助根治性切除术在肝门部胆管癌(pCCA)中的应用尚不明确。本研究旨在评估本研究所机器人辅助pCCA根治术的安全性和有效性。
■2017年7月至2022年7月,中山大学附属第一医院接受机器人辅助和开放根治术的pCCA患者(广州,中国)被包括在内。通过使用倾向评分匹配(PSM)分析比较短期结果。
■纳入86例pCCA患者。在以1:2的比例进行PSM后,将10和20名患者分配到机器人辅助和开放组,分别。两组之间的临床病理特征没有显着差异。机器人辅助组的手术时间明显更长(中位数:548vs353分钟,P=0.004),检查的淋巴结总数(中位数:11vs5,P=0.010)高于开放组。机器人辅助组倾向于术中出血量较低(中位数:125对350mL,P=0.067),输血率(30.0%vs70.0%,P=0.056),术后总体发病率(30.0%vs70.0%,P=0.056)比开放组,即使差异无统计学意义.阴性切缘无显著差异,术后重大疾病,或机器人辅助组和开放组之间的术后住院时间(均P>0.05)。
■机器人辅助的pCCA根治性切除术可能比开放手术获得更多的淋巴结总数。对于选定的pCCA患者,机器人辅助手术可能是可行且安全的技术。
UNASSIGNED: The application of robotic-assisted radical resection in perihilar cholangiocarcinoma (pCCA) remains poorly defined. This study aimed to evaluate the safety and efficacy of robotic-assisted radical resection for pCCA in our institute.
UNASSIGNED: Between July 2017 and July 2022, pCCA patients undergoing robotic-assisted and open radical resection at First Affiliated Hospital of Sun Yat-sen University (Guangzhou,
China) were included. The short-term outcomes were compared by using propensity-scored matching (PSM) analysis.
UNASSIGNED: Eighty-six pCCA patients were enrolled. After PSM at a ratio of 1:2, 10 and 20 patients were assigned to the robotic-assisted and open groups, respectively. There were no significant disparities in the clinicopathological features between the two groups. The robotic-assisted group had significantly longer operation time (median: 548 vs 353 min, P = 0.004) and larger total number of lymph nodes examined (median: 11 vs 5, P = 0.010) than the open group. The robotic-assisted group tended to have a lower intraoperative blood loss (median: 125 vs 350 mL, P = 0.067), blood transfusion rates (30.0% vs 70.0%, P = 0.056), and post-operative overall morbidities (30.0% vs 70.0%, P = 0.056) than the open group, even though the differences were not statistically significant. There were no significant differences in the negative resection margin, post-operative major morbidities, or post-operative length-of-stay between the robotic-assisted and open groups (all P > 0.05).
UNASSIGNED: Robotic-assisted radical resection of pCCA may get a larger total number of lymph nodes examined than open surgery. Provided robotic-assisted surgery may be a feasible and safe technique for selected pCCA patients.