■气道支架,用来恢复气道通畅,主要由恶性气道狭窄患者使用,并偶尔用于一系列其他气道相关疾病,包括导致良性狭窄的情况,malacia,和瘘管。由于介入治疗的改进,正在开发越来越多的气道支架。然而,促进气道支架临床应用的方法仍未确定。在这里,我们通过回顾已发表的研究来描述气道支架的最新进展,为临床决策和进一步研究气道支架提供参考。
■1964年1月至2021年11月的相关文章来自PubMed,WebofScience,EMBASE数据库。术语“金属”,\"硅胶\",\"药物洗脱\",“可生物降解”,“放射性”,\"三维(3D)\",和“支架”以不同的组合进行搜索。主要内容和发现:在这篇综述中,我们专注于各种新型材料和设计的支架的应用方面的最新证据,包括新型金属,新型硅胶,药物洗脱,可生物降解,放射性,和气道狭窄的3D支架。尽管减少了目前所有市售支架的众所周知的并发症,新型支架仍处于起步阶段,没有长期的实用性和安全性记录,但仍然存在一些局限性。在此类支架进入常规临床实践之前,还有更多步骤要采取。
■3D打印方法和可生物降解材料的结合可能为解决与“经典”支架有关的现有问题提供了有希望的途径,并有可能成为未来的主要趋势。
UNASSIGNED: Airway stents, used to restore airway patency, are mostly utilized by patients with malignant airway strictures, and are occasionally used in a range of other airway related diseases, including conditions which result in benign stenosis, malacia, and fistula. There has been an increasing number of airway stents that are being developed thanks to improvements in interventional therapy. However, the method of promoting airway stents for clinical application remains undetermined. Herein, we describe the recent advances in airway stents by reviewing the published studies, providing the reference for clinical decision-making and further research on airway stents.
UNASSIGNED: Relevant articles between January 1964 and November 2021 were obtained from PubMed, Web of Science, and EMBASE databases. The terms \"metallic\", \"silicone\", \"drug-eluting\", \"biodegradable\", \"radioactive\", \"three-dimensional (3D)\", and \"stents\" were searched in different combinations.Key Content and Findings: In this review, we focus on the latest evidence in terms of the application of various stents with novel materials and designs including novel metallic, novel silicone, drug-eluting, biodegradable, radioactive, and 3D stents for airway stenosis. Despite reducing the well-known complications of all current commercially available stents, novel stents are still in their infancy without a long track record of utility and safety, and remain some limitations. There are more steps to be taken before such stents enter routine clinical practice.
UNASSIGNED: A combination of 3D-printing method and biodegradable material may present a promising avenue of solving the existing problems pertaining to \"classic\" stents and has potential to become the main trend in the future.