Ureteral Diseases

输尿管疾病
  • 文章类型: Systematic Review
    背景:输尿管息肉是少见的良性输尿管肿瘤。没有指南建议开放或微创手术是治疗输尿管息肉的最佳方法。本文旨在对目前可用于治疗输尿管息肉的微创技术进行全面综述。材料和方法:我们对PubMed上发表的文章进行了全面搜索,使用关键词“输尿管”和“息肉”,\"或\"息肉。结果:从文献检索中总共获得了275项研究,但排除了96篇文章。结论:随着医学技术的进步,几种微创方法得到了发展,包括内窥镜,腹腔镜,和机器人方法;然而,最佳手术技术尚未确定。由于这些方法的优点和缺点,最好的手术方法应该根据每个病人的需要和外科医生的喜好和经验。
    Background: Ureteral polyps are rare benign ureteral tumor. No guideline recommends that open or minimally invasive surgery is best for treating ureteral polyps. This article aims to provide a comprehensive review of the minimally invasive techniques currently available for treating ureteral polyps. Materials and Methods: We performed a comprehensive search of articles published in PubMed, using the keywords \"ureteral\" and \"polyp,\" or \"polyps.\" Results: A total of 275 studies were obtained from the literature search but 96 articles were excluded. Conclusions: Several minimally invasive approaches were developed with the advancement of medical technology, including endoscopic, laparoscopic, and robotic approaches; however, the best surgical technique was yet to be decided. Due to the advantages and disadvantages of these approaches, the best surgical approach should be tailored to each patient\'s needs and the surgeon\'s preferences and experience.
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  • 文章类型: Journal Article
    目的:介绍我们在机器人或腹腔镜回肠输尿管置换术(IUR)治疗多发性输尿管息肉方面的初步经验。
    方法:在2019年7月至2022年11月期间,连续8例诊断为多发性输尿管息肉的患者接受了机器人或腹腔镜IUR。对5例左侧(n=3)或右侧(n=2)息肉患者进行单侧IUR,3例双侧多发性息肉患者行双侧IUR。人口特征,前瞻性收集围手术期数据和随访结果.
    结果:纳入5名男性和3名女性患者(11个输尿管),平均年龄为32.8±11.3岁。在这些患者中,5例表现为复发性侧腹疼痛,1有血尿,2人无症状。四名患者先前经历过失败的手术干预。患病输尿管的平均长度为11.9±4.7cm,八个侧面超过10厘米。所有程序均成功执行。平均手术时间为319±87.6分钟,其中3例同时接受了术中输尿管镜检查。回肠移植物的平均长度为23.8±5.8cm。平均随访20.4±12.8个月,一个主要的并发症,特别是切口感染,和四个轻微的并发症,包括尿路感染(n=3)和代谢性酸中毒(n=1),被观察到。所有患者都没有症状,肾积水改善/稳定,无再狭窄征象。
    结论:机器人或腹腔镜IUR是可行的,安全,对于多发息肉引起的输尿管长缺损患者的有效手术选择。
    OBJECTIVE: To present our initial experience in the management of multiple ureteral polyps with robotic or laparoscopic ileal ureter replacement (IUR).
    METHODS: Eight consecutive patients diagnosed with multiple ureteral polyps underwent robotic or laparoscopic IUR between July 2019 and November 2022. Unilateral IUR was performed in 5 patients with polyps in the left (n = 3) or right (n = 2) side, and 3 patients with bilateral multiple polyps underwent bilateral IUR. Demographic characteristics, perioperative data and follow-up outcomes were prospectively collected.
    RESULTS: A cohort of 5 male and 3 female patients (11 ureters) with a mean age of 32.8 ± 11.3 years were included. Among these patients, 5 presented with recurrent flank pain, 1 had hematuria, and 2 were asymptomatic. Four patients experienced prior failed surgical interventions. The mean length of diseased ureter was 11.9 ± 4.7 cm, with more than 10 cm in eight sides. All procedures were performed successfully. The mean operation time was 319 ± 87.6 min with 3 patients who simultaneously underwent intraoperative ureteroscopy. The mean length of ileal graft was 23.8 ± 5.8 cm. During the mean follow-up of 20.4 ± 12.8 months, one major complication, specifically incision infection, and four minor complications, including urinary infection (n = 3) and metabolic acidosis (n = 1), were observed. All patients presented symptom-free, with improved/stabilized hydronephrosis and no signs of restenosis.
    CONCLUSIONS: Robotic or laparoscopic IUR is a feasible, safe, and effective surgical option for patients with long ureteral defects caused by multiple polyps.
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  • 文章类型: Letter
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  • DOI:
    文章类型: English Abstract
    目的:探讨2019年冠状病毒病(COVID-19)大流行对泌尿系结石术后患者生活质量(QoL)和心理健康的影响。
    方法:收集2019年12月至2020年6月在泌尿外科内镜碎石术后行输尿管支架置入术患者的人口学和临床资料。收集输尿管支架症状问卷(USSQ)评分和结果20项焦虑自评量表(SAS)和抑郁自评量表(SDS),以评估QoL和精神状态。USSQ由6个领域的44个问题组成(包括泌尿症状,身体疼痛,一般健康,工作表现,性功能,和输尿管支架相关感染)。对于每个领域的大多数问题,其评分为1~5分的Likert型5分量表,小部分问题用1~4或1~7量表量化.SAS和SDS均包含20个问题,用于评估患者的焦虑和抑郁水平。每个项目的评分均为1至4的4分Likert型评分。总分(20至80分)是主要统计指标。通过使用标准分数(总分乘以1.25以产生整数)来量化临床焦虑和抑郁的水平。并通过矩结构分析(AMOS)分析构建了多组结构方程模型。
    结果:总体而言,71例患者被纳入分析。结果发现,对照组和延迟组的输尿管支架时间中位数差异显着,分别为32(30,33)d和94.5(88,103)d,分别。延迟组导致USSQ多维分数更高,其中包括泌尿症状,一般健康,工作表现和输尿管支架相关感染。延迟组的焦虑和抑郁也明显比对照组严重。输尿管支架留置时间越长,尿路症状和躯体疼痛对工作表现的影响越严重(P=0.029<0.05)。其中,尿路症状严重导致工作表现不佳的患者受输尿管支架持续时间延长的影响最大(CR=2.619>1.96).
    结论:因COVID-19导致输尿管支架拔除延迟的患者导致QoL和精神状态恶化。在COVID-19期间,焦虑和抑郁程度较高的患者支架相关症状更严重。为改善COVID-19期间泌尿系结石术后患者的生活质量和心理健康状况,仍不建议延长支架持续时间或采取相应干预措施。
    OBJECTIVE: To explore the impacts of delayed ureteral stent removal on the quality of life (QoL) and mental health of urinary calculi postoperative patients due to the corona virus disease 2019(COVID-19) pandemic.
    METHODS: The demographic and clinical data of patients with ureteral stent placement after urinary endoscopic lithotripsy and returned to Peking University People\'s Hospital for stent removal from December 2019 to June 2020 were collected. Ureteral stent symptoms questionnaire (USSQ) score and the outcome 20-item self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were collected to estimate the QoL and mental status. The USSQ consisted of 44 questions in 6 domains (including urinary symptom, physical pain, general health, work performance, sexual function, and ureteral stent related infection). For most questions in each domain, its score was a five-point Likert-type scale from 1 to 5, and a small proportion of questions was quantified by 1 to 4 or 1 to 7 scale. SAS and SDS both contained 20 questions used to assess a patient\'s level of anxiety and depression. Its scoring for each item was on a four-point Likert-type scale from 1 to 4. A total score (ranging from 20 to 80) was the main statistical indicator. The level of clinical anxiety and depression was quantified by using standard scores (total score multiplied by 1.25 to produce integers). And the multi-group structural equation model was constructed by analysis of moment structure (AMOS) analysis.
    RESULTS: Overall, 71 patients were enrolled for analysis. It was found that the median duration of ureteral stent time differed significantly between the control and delayed groups for 32 (30, 33) d and 94.5 (88, 103) d, respectively. The delayed group resulted in higher scores in the USSQ multidimensional, which included urinary symptoms, general health, work performance and ureteral stent related infections. Anxiety and depression were also significantly serious in the delayed group than in the control group. A longer indwelling time of a ureteral stent could exacerbate the effects of urinary symptoms and physical pain on work performance (P=0.029 < 0.05). Among them, the patients with severe urinary symptoms leading to poor work performance were most significantly affected by prolonged ureteral stent duration time (CR=2.619>1.96).
    CONCLUSIONS: Patients with delayed ureteral stent removal due to the COVID-19 had resulted in worse QoL and mental status. Stents related symptoms are more severe in patients with higher anxiety and depression degree during COVID-19. To improve the QoL and mental health of patients after urinary calculi surgery during COVID-19, it is still not recommended to prolong the stent duration time or corresponding intervention measures should be taken.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    背景技术子宫内膜异位症是一种以子宫内膜组织出现在子宫外为特征的疾病。主要累及腹膜和盆腔器官。输尿管子宫内膜异位症(UE)是罕见的,以累及输尿管的深部浸润性子宫内膜异位症为代表,可导致输尿管梗阻,近端hydrouter,肾积水,肾功能受损。症状可能是隐匿和非特异性的,并可能导致病程延长。我们描述了一名UE并发肾积水的患者。病例报告一名42岁妇女因偶然发现右肾积水而入院泌尿科。经过彻底检查,她接受了右输尿管肿块切除术和右输尿管残端吻合术。病理提示子宫内膜异位症。患者术后立即给予6剂促性腺激素释放激素激动剂,其次是子宫内左炔诺孕酮释放系统。术后随访显示,本年无复发。这里,我们简要总结了流行病学,发病机制,临床表现,成像,治疗,和疾病的预后。结论UE应列为育龄妇女不明原因肾积水的鉴别诊断之一。那些患有痛经的人应该认识到这种疾病。应进行积极的手术治疗和长期管理,以获得更好的预后。
    BACKGROUND Endometriosis is a disease characterized by endometrial tissue appearing outside the uterus, mainly involving the peritoneum and pelvic organs. Ureteral endometriosis (UE) is rare, typified by deep infiltrating endometriosis involving the ureter and can result in ureteral obstruction, proximal hydroureter, hydronephrosis, and impairment of renal function. Symptoms may be insidious and nonspecific and may lead to a prolonged disease course. We describe a patient with UE complicated by hydronephrosis. CASE REPORT A 42-year-old woman was admitted to the Urology Department with the incidental discovery of right hydronephrosis. After a thorough examination, she underwent right ureteral mass resection and right ureteral stump anastomosis. The pathology report indicated endometriosis. The patient was given 6 doses of gonadotropin-releasing hormone agonist immediately after surgery, followed by an intrauterine levonorgestrel-releasing system. Postoperative follow-up showed that no recurrence was observed in this year. Here, we briefly summarize the epidemiology, pathogenesis, clinical presentation, imaging, treatment, and prognosis of the disease. CONCLUSIONS UE should be listed as one of the differential diagnoses of unexplained hydronephrosis in women of childbearing age, and those with dysmenorrhea should be cognizant of this disease. Active surgical treatment and long-term management should be carried out to obtain better prognosis.
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  • 文章类型: Case Reports
    背景:输尿管瘘(AUF)是一种罕见的,危及生命的状况,其中输尿管和普通输尿管之间发生通信,内部,或者髂外动脉.临床常用影像学检查对AUF的敏感性较低,这导致延迟诊断和增加死亡率。此外,输尿管支架使用的增加导致AUF的频率增加.
    方法:我们的两名患者分别为74岁和65岁的男性。他们都有膀胱癌病史,并接受了根治性膀胱切除术并进行了输尿管切除术。患者在1年以上的膀胱切除术中进行了常规导管更换,随后经历了间歇性总体搏动性血尿。在一系列影像学检查未能确定原因后,患者最终诊断为AUF,并接受介入放射治疗,其次是广谱抗生素。发现了积极的效果。
    结论:有相关危险因素的患者,AUF的发生率随着生存期的延长而增加。本病例报告旨在强调AUF的早期诊断和治疗,以降低死亡率。
    BACKGROUND: Arterioureteral fistula (AUF) is a rare, life-threatening condition wherein communication occurs between a ureter and the common, internal, or external iliac artery. The sensitivity of common clinical imaging examination for AUF is low, which leads to a delayed diagnosis and increased mortality. In addition, the increased use of ureteral stents contributes to the growing frequency of AUF.
    METHODS: Our two patients were 74 and 65 years old males respectively. They both had a medical history of bladder cancer and underwent radical cystectomy with ureterocutaneostomy. The patients underwent routine catheter exchange during over 1 year postradical cystectomy and subsequently experienced intermittent gross pulsatile haematuria. After a series of imaging examinations failed to identify the cause, the patients were ultimately diagnosed with AUF and treated with interventional radiotherapy, followed by broad-spectrum antibiotics. Positive effects were found.
    CONCLUSIONS: The incidence of AUF is increased with the prolongation of survival in patients with related risk factors. This case report aims to highlight early diagnosis and management of AUF to lower the mortality.
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  • 文章类型: Journal Article
    背景:本研究的目的是通过植入可流动树脂,在新的兔输尿管结石模型中描述输尿管结石阻塞引起的肾积水的病理生理变化。
    方法:40只新西兰大白兔随机分为2组:结石组和假对照组。在结石组(n=20)中,兔子在左下腹部手术,左输尿管暴露。然后使用0.45mm直径的静脉内输注针将可流动树脂(可流动的修复牙科材料)注射到左输尿管中。然后通过牙科固化光光固化40s以形成结石。在假对照组中,将生理盐水注入输尿管。兔在术前接受X线和血常规及尿常规检查,还有X光片,CT,解剖,术后1、3、5、7天进行HE染色及血常规、尿常规检查。手术后通过X射线和未增强的CT扫描评估结石形成。通过解剖评估病理生理变化,HE染色及血常规、尿常规。
    结果:17只兔成功构建输尿管结石模型。在微积分组中,术后第1天左侧下腹部可见高密度阴影,3rd,第5和第7位通过X射线和CT扫描。解剖发现左输尿管阻塞形成,手术后7天肾盂和输尿管上段扩张。左输尿管的肾脏长径仅在术后第一天增加。HE染色发现术后输尿管和肾脏损害。结石组和假手术组,血清肌酐,尿素氮,手术后第1天白细胞和尿红细胞升高.然而,指标在第3、5和7天恢复正常。
    结论:这是一个稳定的,通过植入可流动树脂,减少了操作的复杂性和成本效益的输尿管结石模型。这种新的模型可能使我们进一步了解输尿管结石梗阻引起的病理生理变化。
    BACKGROUND: The purpose of this study was to characterize the pathophysiological changes of hydronephrosis caused by ureteral calculi obstruction in a new rabbit ureteral calculi model by implanting flowable resin.
    METHODS: Forty New Zealand rabbits were randomly divided into two groups: the calculi group and the sham control group. In the calculi group (n = 20), rabbits were operated at left lower abdomen and the left ureter was exposed. Then flowable resin (flowable restorative dental materials) was injected into the left ureter using a 0.45 mm diameter intravenous infusion needle. Then light-cured for 40 s by means of a dental curing light to form calculi. In the sham control group, normal saline was injected into the ureter. Rabbits underwent X-ray and routine blood and urine tests preoperatively, as well as X-ray, CT, dissection, HE staining and routine blood and urine tests on 1, 3, 5 and 7 days postoperatively. Stone formation was assessed by X-ray and unenhanced CT scan after surgery. The pathophysiological changes were evaluated through dissection, HE staining and routine blood and urine tests.
    RESULTS: Ureteral calculi models were successfully constructed in 17 rabbits. In calculi group, high-density shadows were observed in the left lower abdomen on postoperative day 1st, 3rd, 5th and 7th by X-ray and CT scan. Dissection found obstruction formation of the left ureters, dilatation of the renal pelvis and upper ureter during 7 days after surgery. The renal long-diameters of the left ureters increased only on the 1st postoperative day. HE staining found ureteral and kidney damage after surgery. In calculi group and sham group,the serum creatinine, urea nitrogen, white blood cells and urine red blood cells were raised at day 1 after surgery. However, the indicators returned to normal at day 3, 5, and 7.
    CONCLUSIONS: This is a stable, less complicated operation and cost-effective ureteral calculi model by implanting flowable resin. And this novel model may allow us to further understand the pathophysiology changes caused by ureteral calculi obstruction.
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  • 文章类型: Journal Article
    背景:输尿管阴道瘘(UVF)的手术修复时机正在争论中,在此,我们将介绍我们的经验,以比较早期和延迟输尿管再植术治疗UVF的安全性和有效性.
    方法:2012年1月至2020年1月,22例诊断为UVF的患者接受了输尿管再植术。基线特征,既往腹部手术史,手术概况,收集和分析随访数据。
    结果:在22例诊断为UVF的患者中,12例患者接受了早期输尿管再植术,其他患者接受了延迟输尿管再植术。两组在基线特征和先前手术的详细历史方面具有可比性。早期手术组平均手术时间为140.83±35.28min,延迟手术组为181.00±43.83min(p=0.027)。与延迟手术组(285.00±94.43mL)相比,早期手术组(183.33±107.31mL)患者的失血量较少(p=0.030)。经过34.55个月的总体平均随访,两组输尿管狭窄率差异无统计学意义(早期修复16.67%与40.00%延迟修复,p=0.348)。
    结论:长期结果相似,早期输尿管再植术手术时间短,失血少.此外,等待期间的压力可以最小化。需要具有更大样本量的高质量临床研究来确认早期手术的优越性。
    BACKGROUND: The timing of surgical repair for ureterovaginal fistula (UVF) is under debate, here we introduce our experience to compare the safety and efficacy between early and delayed ureteral reimplantation for UVF.
    METHODS: Between January 2012 and January 2020, 22 patients who were diagnosed with UVF had received ureteral reimplantation. Baseline characteristics, history of previous abdominal surgery, operative profile, and follow-up data were collected and analyzed.
    RESULTS: Among 22 patients diagnosed with UVF, 12 patients received early ureteral reimplantation and others received delayed ureteral reimplantation. Both groups were comparable in baseline characteristics and detailed history of previous operations. The mean operative time of the early surgery group was 140.83 ± 35.28 min, while that of the delayed surgery group was 181.00 ± 43.83 min (p = 0.027). Patients of the early surgery group (183.33 ± 107.31 mL) had less blood loss compared with that of the delayed surgery group (285.00 ± 94.43 mL) (p = 0.030). After an overall mean follow-up of 34.55 months, the ureteral stricture rate of two groups was not statistically significantly different (16.67% in early repair vs. 40.00% in delayed repair, p = 0.348).
    CONCLUSIONS: With similar long-term outcomes, the early ureteral reimplantation had a shorter operative time and less blood loss. Moreover, the stress during the waiting period could be minimized. High-quality clinical studies with larger sample size are needed to confirm the superior nature of early surgery.
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  • 文章类型: Case Reports
    肾动静脉畸形(RAVM)是一种罕见的病理。它可能会出现心血管疾病,高血压,充血性心力衰竭.数字减影血管造影(DSA)是标准的诊断选择,在大多数情况下,血管内栓塞是首选的治疗方法。据报道,RAVM的摄食分支起源于肾动脉。在这份报告中,1例43岁女性,复发性大量血尿和左侧腹疼痛.肾血管造影显示双肾动脉供应左肾和肾盂周围多个肾动静脉瘘形成。用线圈和明胶海绵进行栓塞,然后血尿消退。一个月后,由于大量体力活动后血尿复发,患者再次入院。DSA发现RAVM的另一条供血动脉起源于第四腰椎周围的主动脉。在这个动脉馈线栓塞后,血尿解决了。在10个月的随访中没有复发。据我们所知,这是首例肾外供血动脉的RAVM,这种情况的遗漏可能导致治疗失败。
    Renal arteriovenous malformation (RAVM) is a rare pathology. It may present with heamturia, hypertension, and congestive heart failure. Digital subtraction angiography (DSA) is the standard diagnostic choice, and endovascular embolization is a preferred procedure of management in most cases. The feeding branches of RAVM are reported to originate from renal arteries. In this report, a 43-year-old female with recurrent massive hematuria and left flank pain was described. Renal angiography revealed double renal arteries supplying the left kidney and multiple renal arteriovenous fistula formation around the renal pelvis. Embolization with coils and gelfoam was performed after which her hematuria subsided. One month later, the patient was readmitted to our hospital due to the relapse of massive hematuria following heavy physical activities. DSA found another feeding artery of the RAVM originating from the aorta around the 4th lumbar vertebra. After embolization of this arterial feeder, hematuria settled. There was no recurrence during a 10-month follow-up. To our knowledge, this is the first case of RAVM with an extrarenal feeding artery, and omission of this scenario can lead to treatment failure.
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