背景：持续增生性原发性玻璃体（PHPV）是一种罕见的先天性发育性眼部疾病，由胚胎玻璃样脉管系统的不完全消退引起。在这里，我们报告了一例非手术的单侧前PHPV，该病例通过弱视治疗进行了治疗，并改善了视力和胎儿脉管系统的消退。
方法：一名三岁女孩被诊断为左眼单侧前PHPV，表现为后极白内障，后囊混浊,小扁豆膜,和一条漂浮的玻璃样动脉连接到后牙肿块。斑块不够大，无法填满瞳孔，并进行保守治疗和弱视治疗。十九个月后,视力在受影响的眼睛从20/100提高到20/50矫正，胎儿血管逐渐消退，最后变成无灌注的幽灵血管。
结论：在受PHPV影响的儿童中，可以观察到胎儿脉管系统的回归，保守治疗和弱视治疗可能有助于视力改善。
BACKGROUND: Persistent hyperplastic primary vitreous (PHPV) is a rare congenital developmental ocular disorder caused by incomplete regression of the embryonic hyaloid vasculature. Here we report a case of nonsurgical unilateral anterior PHPV that was managed by amblyopia treatment and resulted in an improvement of visual acuity and regression of the fetal vasculature.
METHODS: A three-year-old girl was diagnosed with unilateral anterior PHPV in the left eye, manifested with posterior pole cataract, posterior capsule opacification, tunica vasculosa lentis, and a floating hyaloid artery connected to the retrolental mass. The plaque was not large enough to fill the pupil, and conservative management along with amblyopia treatment was conducted. Nineteen months later, the visual acuity in the affected eye improved from 20/100 to 20/50 with correction, and the fetal vasculature regressed gradually and finally into a nonperfusion ghost vessel.
CONCLUSIONS: In PHPV-affected children, regression of the fetal vasculature may be observed, and conservative management and amblyopia treatment may be helpful for visual improvement.
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