未经证实:气管拔管可能与多种并发症有关,包括去饱和,激动,高血压,和心动过速.我们假设在深度麻醉下拔管后立即使用经鼻增湿快速吹气呼吸机交换(THRIVE)可降低这些不良事件的发生率。
UNASSIGNED:将100名在全身麻醉下进行择期腹部手术的患者随机分配到深度麻醉下采用THRIVE(THRIVE组)或清醒拔管(对照组)进行气管拔管。主要结果是在麻醉出现期间的任何时间经历去饱和(SpO2<90%)的发生率。次要结果包括心率和血压的变化,舒适度,bucking,和激动。
未经证实:THRIVE组的去饱和发生率低于对照组(12vs.54%,OR=0.22[95%CI,0.10-0.49],P<0.001)。THRIVE组患者平均动脉压升高20%(或更多)(4vs.26%,OR=0.15[95%CI,0.04-0.65],P=0.002)。THRIVE患者没有躁动或呕吐,而在对照组中,22%和58%的患者发生了躁动和呕吐,分别。此外,THRIVE组的不适经历发生率低于对照组(8vs.36%,OR=0.22[95%CI,0.08-0.61],P=0.001)。
UNASSIGNED:深度麻醉下使用THRIVE的气管拔管降低了去饱和和不良血流动力学事件的发生率,并提高了患者的满意度。在选定的患者人群中,深度麻醉下使用THRIVE拔管可能是一种替代策略。
UNASSIGNED: Tracheal extubation can be associated with several complications, including desaturation, agitation, hypertension, and tachycardia. We hypothesize that the use of transnasal humidified rapid insufflation ventilator exchange (
THRIVE) immediately after extubation under deep anesthesia reduces the incidence of these adverse events.
UNASSIGNED: One hundred patients who underwent elective abdominal surgery under general anesthesia were randomly assigned to undergo tracheal extubation under deep anesthesia employing THRIVE (
THRIVE group) or awake extubation (CONTROL group). The primary outcome was the incidence of experiencing desaturation (SpO2 < 90%) at any time during emergence from anesthesia. Secondary outcomes included variations in heart rate and blood pressure, comfort level, bucking, and agitation.
UNASSIGNED: The
THRIVE group showed a lower incidence of desaturation than the CONTROL group (12 vs. 54%, OR = 0.22 [95% CI, 0.10-0.49], P < 0.001). Less patients in the
THRIVE group experienced a 20% (or more) increase in mean arterial pressure (4 vs. 26%, OR = 0.15 [95% CI, 0.04-0.65], P = 0.002). THRIVE patients did not suffer from agitation or bucking, while in the CONTROL group agitation and bucking occurred in 22 and 58% of the patients, respectively. Additionally, the
THRIVE group showed a lower incidence of uncomfortable experience than the CONTROL group (8 vs. 36%, OR = 0.22 [95% CI, 0.08-0.61], P = 0.001).
UNASSIGNED: Tracheal extubation under deep anesthesia using THRIVE decreases the incidence of desaturation and adverse haemodynamic events and increases patient satisfaction. Extubation under deep anesthesia using THRIVE might be an alternative strategy in selected patient populations.