未经证实：卒中相关感染(SAI)是卒中后常见的并发症。肌少症患者的感染发生率高于普通人群。然而,老年患者卒中前肌少症风险与SAI之间的关系尚未得到证实.本研究旨在探讨老年急性缺血性卒中（AIS）患者卒中前期肌肉减少症风险与SAI之间的关系。
UNASSIGNED：本回顾性研究由北京大学人民医院进行。我们通过应用SARC-F问卷评估了中风前肌肉减少症的风险。应用多因素logistic回归分析卒中前肌少症风险与SAI的关系。
UNASSIGNED：共有1,002名患有AIS的老年患者（592名男性；72.9±8.6岁）被纳入本研究。在29.1%的队列中发现了卒中前肌肉减少症的风险。SAI组中卒中前肌少症风险患者的比例高于非SAI组（43.2vs.25.3%,p<0.001)。在多变量逻辑分析中，校正潜在因素后,卒中前肌肉减少症风险与SAI独立相关(OR=1.454,95%CI:1.008-2.097,p=0.045).这种关联在基于年龄的亚组中保持一致，性别,身体质量指数,吸烟状况,饮酒状况,糖尿病,高血压,和血脂异常。
UNASSIGNED：在老年AIS患者中，卒中前肌少症风险与SAI独立相关。我们的发现强调了在该人群中，卒中前肌少症的识别在SAI的预防和管理中的重要性。
UNASSIGNED: Stroke-associated infection (SAI) is a common complication after a stroke. The incidence of infection was higher in people with sarcopenia than in the general population. However, the relationship between pre-stroke sarcopenia risk and SAI in older patients has not been confirmed. This study aimed to investigate the association between pre-stroke sarcopenia risk and SAI in older patients with acute ischemic stroke (AIS).
UNASSIGNED: This retrospective study was conducted by the Peking University People\'s Hospital. We evaluated the pre-stroke sarcopenia risk by applying the SARC-F questionnaire. Multivariate logistic regression was applied to explore the association between pre-stroke sarcopenia risk and SAI.
UNASSIGNED: A total of 1,002 elder patients with AIS (592 men; 72.9 ± 8.6 years) were enrolled in our study. Pre-stroke sarcopenia risk was found in 29.1% of the cohort. The proportion of patients with pre-stroke sarcopenia risk was larger in the SAI group than in the non-SAI group (43.2 vs. 25.3%, p < 0.001). In multivariate logistic analysis, pre-stroke sarcopenia risk was shown to be independently associated with SAI (OR = 1.454, 95% CI: 1.008-2.097, p = 0.045) after adjusting for potential factors. This association remained consistent across the subgroups based on age, sex, body mass index, smoking status, drinking status, diabetes, hypertension, and dyslipidemia.
UNASSIGNED: Pre-stroke sarcopenia risk was independently associated with SAI in older patients with AIS. Our findings highlight the significance of pre-stroke sarcopenia identification in the prevention and management of SAI in this population.
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