Radiculopathy

神经根病
  • 文章类型: Journal Article
    探讨神经根型颈椎病(CSR)患者潜在的颈椎不稳和颈椎肌肉退变是否影响颈椎牵引的疗效,以及颈椎牵引是否会加剧颈椎的潜在不稳定。根据水平位移和异常角度的差异,将113例CRS患者分为三组,并通过MRI测量患者的颈椎肌肉退变程度。考虑到功能分数,VAS,3组治疗后NDI和PCS评分均有明显改善。通过组间分析,我们发现,轻度和中度不稳定趋势组的功能评分改善优于重度组.通过核磁共振测量,我们发现,严重不稳定趋势组的颈椎肌肉退变程度显著增加。关于治疗前后X射线成像参数的变化,治疗前后无显著差异.对于CSR患者,他们对颈椎不稳定的倾向越严重,颈椎肌肉退化程度越严重,这意味着疗效越差,但颈椎牵引并没有加重颈椎不稳的潜在程度。
    To explore whether the potential instability of the cervical spine and cervical muscle degeneration in patients with cervical spondylotic radiculopathy (CSR) affect the efficacy of cervical traction, and whether cervical traction can aggravate the potential instability of the cervical spine. We divided the 113 recruited CRS patients into three groups based on the differences in horizontal displacement and abnormal angle, and measured the degree of cervical muscle degeneration in the patients through MRI. Considering functional scores, VAS, NDI and PCS scores of the three groups post-treatment were significantly improved. Through the intergroup analysis, we found that the improvement in functional scores in the mild and moderate instability trend groups was better than that in the severe group. Through MRI measurements, we found that the degree of cervical muscle degeneration was significantly increased in the severe instability trend group. Regarding the changes in X-Ray imaging parameters pre- and post-treatment, no significant differences were observed pre- and post-treatment. For patients with CSR, the more serious their predisposition for cervical instability was, the more severe the degree of cervical muscle degeneration was, which means the worse the curative effect was, but cervical traction did not aggravate the potential degree of cervical instability.
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  • 文章类型: Journal Article
    目的:本研究旨在比较单侧双向内镜(UBE)和经皮内镜(PE)减压治疗神经根型颈椎病(CSR)的临床疗效和并发症发生率。
    方法:截至2024年4月,对多个数据库进行了全面的文献综述,包括EMBASE,PubMed,科克伦图书馆,中国国家知识基础设施,和万方数据,重点是比较UBE与PE在CSR后路椎间孔切开术和椎间盘切除术减压术中的临床研究。荟萃分析的重点是评估临床结果,如手术时间,失血,切口长度,颈部残疾指数(NDI)颈部疼痛和手臂疼痛的视觉模拟量表(VAS),和并发症。
    结果:从电子数据库中确定的最初1,041项研究中,八人根据头衔被认为是合格的,abstract,全文筛选。这些研究涉及552名患者(269名男性,283名女性;平均年龄:53.9±11.4岁;范围,30至79岁),UBE组287人,PE组265人。Meta分析显示,UBE与PE手术时间差异无统计学意义(均差[MD]=-3.68;95%置信区间[CI]:-19.38,12.02;p=0.65)。然而,与UBE组相比,PE组的失血量(MD=17.01;95%CI:2.61,31.41;p=0.02)和切口长度(MD=11.62;95%CI:9.23,14.01;p<0.00001)均显著较低.关于临床结果,两组在NDI方面没有观察到显著差异(MD=0.12;95%CI:-0.10,0.34;0.28),颈部疼痛的VAS(MD=-0.06;95%CI:-0.19,0.06;p=0.32),手臂疼痛的VAS(MD=-0.14;95%CI:-0.26,-0.01;p=0.84),或并发症(OR=1.07;95%CI:0.54,2.10;p=0.85)。
    结论:我们的研究结果表明,UBE和PE之间的临床结果没有显着差异,包括NDI,手臂疼痛的VAS,和颈部疼痛的VAS,以及并发症发生率。值得注意的是,与体育相比,治疗CSR时,UBE导致出血增加和切口长度延长,而不会大幅减少操作时间。
    OBJECTIVE: This study aimed to compare the clinical efficacy and complication rates of decompression with unilateral biportal endoscopy (UBE) and percutaneous endoscopy (PE) in cervical spondylotic radiculopathy (CSR).
    METHODS: A comprehensive literature review was conducted up to April 2024 across multiple databases, including EMBASE, PubMed, Cochrane Library, China National Knowledge Infrastructure, and Wanfang Data, focusing on clinical studies that compare UBE with PE for posterior foraminotomy and discectomy decompression in CSR. The meta-analysis was performed with an emphasis on evaluating clinical outcomes such as operation time, blood loss, incision length, Neck Disability Index (NDI), Visual Analog Scale (VAS) for neck pain and arm pain, and complications.
    RESULTS: Out of an initial 1,041 studies identified from electronic databases, eight were deemed eligible based on title, abstract, and full-text screening. These studies involved 552 patients (269 males, 283 females; mean age: 53.9±11.4 years; range, 30 to 79 years), with 287 in the UBE group and 265 in the PE group. Meta-analysis indicated no significant difference in operation time between UBE and PE (mean difference [MD]=-3.68; 95% confidence interval [CI]:-19.38, 12.02; p=0.65). However, both blood loss (MD=17.01; 95% CI: 2.61, 31.41; p=0.02) and incision length (MD=11.62; 95% CI: 9.23, 14.01; p<0.00001) were significantly lower in the PE group compared to the UBE group. Regarding clinical outcomes, no significant differences were observed between the two groups in terms of NDI (MD=0.12; 95% CI:-0.10, 0.34; 0.28), VAS for neck pain (MD=-0.06; 95% CI:-0.19, 0.06; p=0.32), VAS for arm pain (MD=-0.14; 95% CI:-0.26, -0.01; p=0.84), or complications (OR=1.07; 95% CI: 0.54, 2.10; p=0.85).
    CONCLUSIONS: Our findings suggest that there are no significant disparities in clinical outcomes between UBE and PE, encompassing NDI, VAS for arm pain, and VAS for neck pain, as well as complication rates. Notably, compared to PE, UBE results in increased bleeding and longer incision lengths when treating CSR, without substantially reducing operation time.
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  • 文章类型: English Abstract
    目的:观察经络推拿治疗神经根型颈椎病的临床疗效。
    方法:将2020年3月至2023年6月收治的神经根型颈椎病患者64例分为观察组和治疗组,每组32例。观察组接受常规治疗,男14例,女18例,平均年龄(41.34±7.23)岁,年龄32~55岁;病程9~17个月,平均(14.23±3.56)个月;C5、C6神经根受压12例,17例发生C7神经根压迫,3例发生C8神经根压迫。治疗组在常规治疗的基础上给予推拿治疗,男17例,女15例,平均年龄(40.86±6.97)岁,年龄30~54岁;病程8~18个月,平均(15.43±3.48)个月;C5、C6神经根受压14例,16例发生C7神经根压迫,2例发生C8神经根压迫。采用视觉模拟评分法(VAS)评价临床疗效,颈残疾指数(NDI)和颈椎病临床评定量表(CASCS)治疗前后2周,比较治疗前后颈椎活动度。
    结果:治疗2周后,治疗组和观察组的VAS和NDI评分降低,CASCS评分升高(P<0.001)。治疗2周后,治疗组VAS、NDI评分低于观察组,CASCS评分高于观察组(P<0.001)。与治疗前相比,屈曲的运动范围,扩展,左屈曲,右屈曲,两组治疗2周后左旋转和右旋转均增加(P<0.05)。与观察组相比,屈曲的运动范围,扩展,左屈曲,右屈曲,治疗组左旋转和右旋转增加更显著(P<0.05)。
    结论:经络推拿治疗神经根型颈椎病有效,可以有效缓解颈部疼痛,改善临床症状,提高患者满意度。
    OBJECTIVE: To observe the clinical efficacy of meridian massage in the treatment of cervical spondylotic radiculopathy.
    METHODS: Sixty-four patients with cervical radiculopathy treated from March 2020 to June 2023 were divided into the observation group and the treatment group, with 32 cases in each group. The observation group received conventional treatment, including 14 males and 18 females with an average age of (41.34±7.23) years old ranging from 32 to 55 years old;the disease duration ranged from 9 to 17 months with an average of (14.23±3.56) months;C5 and C6 nerve root compression occurred in 12 cases, C7 nerve root compression occurred in 17 cases, C8 nerve root compression occurred in 3 cases. The treatment group received massage therapy on the basis of conventional treatment, including 17 males and 15 females with an average age of (40.86±6.97) years old ranging from 30 to 54 years old;the disease duration ranged from 8 to 18 months with an average of (15.43±3.48) months;C5 and C6 nerve root compression occurred in 14 cases, C7 nerve root compression occurred in 16 cases, C8 nerve root compression occurred in 2 cases. The clinical efficacy was evaluated by visual analogue scale(VAS), neck disability index(NDI) and clinical assessment scale for cervical spondylosis(CASCS) before and after 2-week treatment, and the range of motion of cervical spine was compared before and after treatment.
    RESULTS: After 2-week treatment, the VAS and NDI scores of the treatment group and the observation group decreased, while the CASCS scores increased(P<0.001). After 2-week treatment, the VAS and NDI scores were lower and the CASCS scores were higher in the treatment group than those of the observation group(P<0.001). Comparing with those before treatment, the range of motion of flexion, extension, left flexion, right flexion, left rotation and right rotation after 2-week treatment increased in two groups(P<0.05). Comparing with the observation group, the range of motion of flexion, extension, left flexion, right flexion, left rotation and right rotation increased more significantly in the treatment group(P<0.05).
    CONCLUSIONS: Meridian massage is effective in the treatment of cervical Spondylotic radiculopathy, which can effectively relieve neck pain, improve clinical symptoms and improve patient satisfaction.
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  • 文章类型: Journal Article
    目的:目的是确定特定的身体活动(PA)或心理压力因素是否与不同的爆发定义相关(疼痛定义的耀斑[PDF]:持续至少2小时的疼痛加重期,当疼痛强度明显比最近更糟糕时;和非疼痛定义的耀斑[NPDF]:明显不舒服的感觉,比如疲劳,功能丧失,或情绪/心理波动,在腰椎神经根性疼痛患者中,基于11点量表的疼痛强度没有重大波动)。
    方法:这是一项病例交叉研究。患有急性或亚急性腰椎根性疼痛的参与者以3天的间隔完成了为期6周的连续面对面或在线评估,以确定他们在特定类型的PA或心理压力后是否经历了坐骨神经痛发作(PDF/NPDF)。
    结果:共有152名参与者入组。有597个PDF和323个NPDF病例期和800个控制期。长时间的步行和站立增加了PDF的几率,长时间坐着会增加NPDF的几率,精神痛苦,和抑郁的情绪。根据多变量分析,长时间坐着(OR:3.0,95%CI:1.7-5.5),长时间行走(OR:6.2,95%CI:3.9-9.9),长时间站立(OR:5.6,95%CI:3.3-9.5)与PDF的几率显着相关,和长时间坐着(OR:3.4,95%CI:1.8-6.2),精神困扰(OR:6.7,95%CI:2.5-17.5),和抑郁情绪(OR:5.8,95%CI:2.6-12.8)与NPDF的几率相关。
    结论:长时间坐着,走路,和站立触发了PDF的发生。长时间坐着,精神痛苦,情绪低落引发了NPDF的发生。
    OBJECTIVE: The objective was to determine whether specific physical activity (PA) or psychological stress factors are associated with different definitions of flare-ups (pain-defined flares [PDFs]: periods of increased pain lasting at least 2 h, when pain intensity is distinctly worse than it has been recently; and non-pain-defined flares [NPDFs]: obviously uncomfortable feelings, such as fatigue, loss of function, or emotional/psychosocial fluctuations, without major fluctuations in pain intensity based on 11-point scales) among people with lumbar radicular pain.
    METHODS: This was a case-crossover study. Participants with acute or subacute lumbar radicular pain completed serial face-to-face or online assessments for 6 weeks at 3-day intervals to determine whether they experienced sciatica flare-ups (PDF/NPDF) after specific types of PA or psychological stresses.
    RESULTS: A total of 152 participants were enroled. There were 597 PDF and 323 NPDF case periods and 800 control periods. The odds of PDFs were increased by prolonged walking and standing, and the odds of NPDFs were increased by prolonged sitting, mental distress, and depressed mood. According to the multivariable analyses, prolonged sitting (OR: 3.0, 95% CI: 1.7-5.5), prolonged walking (OR: 6.2, 95% CI: 3.9-9.9), and prolonged standing (OR: 5.6, 95% CI: 3.3-9.5) were significantly associated with the odds of PDFs, and prolonged sitting (OR: 3.4, 95% CI: 1.8-6.2), mental distress (OR: 6.7, 95% CI: 2.5-17.5), and depressed mood (OR: 5.8, 95% CI: 2.6-12.8) associated with the odds of NPDFs.
    CONCLUSIONS: Prolonged sitting, walking, and standing triggered the occurrence of PDF. Prolonged sitting, mental distress, and depressed mood triggered the occurrence of NPDF.
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  • 文章类型: Journal Article
    目的:观察微创颈后路椎间孔切开术(MI-PCF)和颈前路椎间盘切除融合术(ACDF)治疗单节段单侧神经根病(SLUCR)的临床疗效和安全性。
    方法:我们回顾性分析了2020年2月至2022年2月两家医院的81例SLUCR患者,包括MI-PCF组(n=40)和ACDF组(n=41)。颈部和肩部疼痛的差异,视觉模拟评分(VAS),上肢放射痛(VAS),比较颈部残疾指数(NDI)。手术时间,术中出血,住院,比较两组患者的并发症。
    结果:ACDF组术后1天的颈肩疼痛缓解程度优于MI-PCF组(p<0.05),而两组在1个月时颈肩疼痛缓解方面无显著差异,3个月,6个月,术后12个月,(p>0.05)。1天时两组上肢放射痛的缓解和NDI评分的降低无显著性差异,1个月,3个月,6个月,术后12个月(p>0.05)。MI-PCF组患者手术时间短,出血少,缩短住院时间,差异有统计学意义(p<0.05)。两组并发症发生率无统计学差异。(p>0.05)。
    结论:MI-PCF和ACDF治疗SLUCR的临床疗效和安全性均满意。同时,MI-PCF手术时间短,与ACDF相比,出血少,住院时间短,值得临床推广。
    OBJECTIVE: The aim of this study was to observe the clinical efficacy and safety of minimally invasive posterior cervical foraminotomy (MI-PCF) and anterior cervical discectomy and fusion (ACDF) in the treatment of single-level unilateral cervical radiculopathy (SLUCR).
    METHODS: We retrospectively analyzed 81 patients with SLUCR in two hospitals from February 2020 to February 2022, including the MI-PCF group (n=40) and the ACDF group (n=41). The differences in neck and shoulder pain, visual analog score (VAS), upper limb radiating pain (VAS), and neck disability index (NDI) were compared. Operative time, intraoperative bleeding, hospital stay, and complications were also compared between the two groups.
    RESULTS: The degree of neck and shoulder pain relief at 1 day postoperatively was better in the ACDF group than in the MI-PCF group (p<0.05), while there were no significant differences between the two groups in terms of neck and shoulder pain relief at 1 month, 3 months, 6 months, and 12 months postoperatively, (p>0.05). There were no significant differences in the relief of upper limb radiating pain and the decrease of NDI scores between the two groups at 1 day, 1 month, 3 months, 6 months, and 12 months after surgery (p>0.05). The patients in MI-PCF group had shorter operative time, less bleeding, and shorter hospital stay, which were statistically different (p<0.05). There was no statistical difference in the complication rate between the two groups, (p>0.05).
    CONCLUSIONS: The clinical efficacy and safety of MI-PCF and ACDF in the treatment of SLUCR are satisfactory, meanwhile, MI-PCF has shorter operative time, less bleeding and shorter hospital stay than ACDF, which is worthy of clinical promotion.
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  • 文章类型: Journal Article
    背景:颈椎病(CS),包括脊髓病和神经根病,是最常见的退行性颈椎疾病。本研究旨在评估与常规颈椎前路减压融合术(ACDF)相比,单侧双门静脉内窥镜(UBE)治疗单侧颈神经根病或单侧颈椎间盘突出症引起的并发颈脊髓病的临床疗效。
    方法:前瞻性,随机化,控制,进行了非劣效性试验.样本包括131例患者,他们在2021年9月至2022年9月期间接受了UBE或ACDF。将具有颈神经根或共存脊髓压迫症状和影像学定义的单侧颈神经根病或单侧颈椎间盘突出症引起的并发颈脊髓病的患者随机分为两组:UBE组(n=63)和ACDF组(n=68)。手术时间,失血,手术后住院时间,记录围手术期并发症。术前和术后改良日本骨科协会(mJOA)量表评分,视觉模拟量表(VAS)评分,颈部残疾指数(NDI)评分,mJOA的恢复率(RR)用于评估临床结局。
    结果:接受UBE治疗的患者术后住院时间明显短于接受ACDF治疗的患者(p<0.05)。颈部或手臂VAS评分无显著差异,NDI得分,MJOA得分,或两组间mJOA的平均RR(p<0.05)。两组仅观察到轻度并发症,无显著性差异(p=0.30)。
    结论:UBE可显著缓解疼痛和残疾,无严重并发症,大多数患者对这种技术感到满意。因此,该手术可安全有效地替代ACDF用于治疗单侧颈神经根病或单侧颈椎间盘突出症引起的并发颈脊髓病.
    背景:这项研究于2023年2月08日在中国临床试验注册中心注册(http://www.chictr.org.cn,#ChiCTR2300074273)。
    BACKGROUND: Cervical spondylosis (CS), including myelopathy and radiculopathy, is the most common degenerative cervical spine disease. This study aims to evaluate the clinical outcomes of unilateral biportal endoscopy (UBE) compared to those of conventional anterior cervical decompression and fusion (ACDF) for treating unilateral cervical radiculopathy or coexisting cervical myelopathy induced by unilateral cervical herniated discs.
    METHODS: A prospective, randomized, controlled, noninferiority trial was conducted. The sample consisted of 131 patients who underwent UBE or ACDF was conducted between September 2021 and September 2022. Patients with cervical nerve roots or coexisting spinal cord compression symptoms and imaging-defined unilateral cervical radiculopathy or coexisting cervical myelopathy induced by unilateral cervical herniated discs were randomized into two groups: a UBE group (n = 63) and an ACDF group (n = 68). The operative time, blood loss, length of hospital stay after surgery, and perioperative complications were recorded. Preoperative and postoperative modified Japanese Orthopaedic Association (mJOA) scale scores, visual analog scale (VAS) scores, neck disability index (NDI) scores, and recovery rate (RR) of the mJOA were utilized to evaluate clinical outcomes.
    RESULTS: The hospital stay after surgery was significantly shorter in patients treated with UBE than in those treated with ACDF (p < 0.05). There were no significant differences in the neck or arm VAS score, NDI score, mJOA score, or mean RR of the mJOA between the two groups (p < 0.05). Only mild complications were observed in both groups, with no significant difference (p = 0.30).
    CONCLUSIONS: UBE can significantly relieve pain and disability without severe complications, and most patients are satisfied with this technique. Consequently, this procedure can be used safely and effectively as an alternative to ACDF for treating unilateral cervical radiculopathy or coexisting cervical myelopathy induced by unilateral cervical herniated discs.
    BACKGROUND: This study was registered in the Chinese Clinical Trial Registry on 02/08/2023 ( http://www.chictr.org.cn , #ChiCTR2300074273).
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  • 文章类型: Journal Article
    背景:为了确定灵敏度,特异性,红外热成像在诊断腰骶神经根疼痛中的总体诊断准确性。
    方法:纳入依次出现下肢疼痛的患者。临床确定性评分范围为0至10,用于评估腰骶神经根疼痛的可能性,更高的分数表明更高的可能性。进行红外热成像扫描并将温度差(ΔT)计算为ΔT=T1-T2,其中T2表示受影响肢体上最疼痛区域的皮肤温度,T1表示未受影响肢体上相同区域的皮肤温度。出院后,两名独立医生根据术中发现诊断腰骶部神经根疼痛,手术效果,和医疗记录。
    结果:共有162名患者被纳入研究,裁定的金标准诊断显示101(62%)患者患有腰骶神经根疼痛,61例患者的下肢疼痛归因于其他疾病。ΔT的最佳诊断值确定在0.8℃和2.2℃之间,具有相应的诊断准确性,灵敏度,和80%的特异性,89%,分别为66%。诊断的准确性,灵敏度,临床确定性评分的特异性报告为69%,62%,分别为79%。将临床确定性评分与ΔT相结合可获得诊断准确性,灵敏度,和84%的特异性,77%,分别为88%。
    结论:红外热成像被证明是诊断腰骶神经根疼痛的高度敏感工具。在一般临床评估可能无法提供结论性结果的情况下,它提供了额外的诊断价值。
    背景:ChiCTR2300078786,19/22/2023。
    BACKGROUND: To identify the sensitivity, specificity, and overall diagnostic accuracy of infrared thermography in diagnosing lumbosacral radicular pain.
    METHODS: Patients sequentially presenting with lower extremity pain were enrolled. A clinical certainty score ranging from 0 to 10 was used to assess the likelihood of lumbosacral radicular pain, with higher scores indicating higher likelihood. Infrared Thermography scans were performed and the temperature difference (ΔT) was calculated as ΔT = T1 - T2, where T2 represents the skin temperature of the most painful area on the affected limb and T1 represents the skin temperature of the same area on the unaffected limb. Upon discharge from the hospital, two independent doctors diagnosed lumbosacral radicular pain based on intraoperative findings, surgical effectiveness, and medical records.
    RESULTS: A total of 162 patients were included in the study, with the adjudicated golden standard diagnosis revealing that 101 (62%) patients had lumbosacral radicular pain, while the lower extremity pain in 61 patients was attributed to other diseases. The optimal diagnostic value for ΔT was identified to fall between 0.8℃ and 2.2℃, with a corresponding diagnostic accuracy, sensitivity, and specificity of 80%, 89%, and 66% respectively. The diagnostic accuracy, sensitivity, and specificity for the clinical certainty score were reported as 69%, 62%, and 79% respectively. Combining the clinical certainty score with ΔT yielded a diagnostic accuracy, sensitivity, and specificity of 84%, 77%, and 88% respectively.
    CONCLUSIONS: Infrared thermography proves to be a highly sensitive tool for diagnosing lumbosacral radicular pain. It offers additional diagnostic value in cases where general clinical evaluation may not provide conclusive results.
    BACKGROUND: ChiCTR2300078786, 19/22/2023.
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  • 文章类型: Journal Article
    The paper introduces professor ZHANG Weihua\'s experience in treatment of cervical spondylotic radiculopathy (CSR) with ulna-tibia needling therapy combined with decompression-loosening manual manipulation. Using \"palpating, detecting and imaging observing\", professor ZHANG Weihua gives the accurate diagnosis for the location, the stage and the severity of the disease. According to the nature of the disease, CSR is treated in three stages. He proposes the academic thought, \"taking the tendons as the outline, regarding the meridians as the essential, rooting at qi and blood, co-regulating tendons and bones\". The ulna-tibia needling therapy and decompression-loosening manual manipulation are combined in treatment. In the ulna-tibia needling therapy, the acupuncture is delivered at the lower 1/3 of the cutaneous regions of taiyang and shaoyang meridians, on the ulnar region (belt-like distribution). The decompression-loosening manual manipulation is operated in 3 steps, i.e. relaxing the nape region, decompressing and relaxing (includes positioning rotational wrenching, upward and backward elevation) and supination wrenching, and analgesia and regulating tendons; and the manipulation for analgesia and regulating tendons is supplemented to enhance the effect.
    介绍张卫华教授运用尺胫针疗法结合减压松动手技治疗神经根型颈椎病的经验。张卫华教授采用“二摸三查两阅”法对疾病的病位、分期、程度进行精确诊断,根据疾病的性质认为神经根型颈椎病当从3期论治,提出“以筋为纲,以经为要,以气血为基,筋骨并调”的学术思想,运用尺胫针疗法结合减压松动手技进行治疗。尺胫针选取太阳、少阳经尺部之区带的下1/3皮部(带状)范围进针;减压松动手技分为放松颈项、减压松动(包括定位旋转扳法、上抬后顶法、仰侧扳法)、镇痛理筋3步,并配合镇痛理筋手法加强疗效。.
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  • 文章类型: Journal Article
    OBJECTIVE: To observe the clinical efficacy and safety of ultrasound-guided acupotomy in adjuvant treatment of residual symptoms after percutaneous cervical disc nucleoplasty (PCDN) for cervical spondylotic radiculopathy (CSR).
    METHODS: A total of 70 CSR patients were divided into treatment group and control group according to random number table, with 35 cases in each group. Patients in the control group received PCDN, while patients in the treatment group further received ultrasound-guided acupotomy, which was performed once every 5 to 7 days for a total of 4 to 6 times (adjusted according to the condition of patients). The visual analog score (VAS), neck dysfunction index (NDI), Japanese Orthopaedic Association cervical spondylosis scale (JOA score), and Tanaka Yasuhisa 20-point scale were adopted in the assessment before PCDN and 1 day, 1 month, 3 months, 6 months after PCDN. The clinical efficacy, postoperative adverse reactions and complications of the 2 groups were evaluated.
    RESULTS: Compared with those before PCDN, the VAS score and NDI score of the 2 groups were decreased (P<0.05), JOA score and Tanaka Yasuhisa 20-point score were increased (P<0.05) at 1 day and 1, 3 and 6 months after surgery. Compared with same group 1 day after surgery, the VAS score and NDI score of the treatment group were decreased (P<0.05), while JOA score and Tanaka Yasuhisa 20-point score were increased (P<0.05) at 1, 3 and 6 months after surgery. Compared with the control group at the same time points, the VAS score and NDI score of the treatment group were decreased (P<0.05), while JOA score and Tanaka Yasuhisa 20-point score were increased (P<0.05) at 1, 3 and 6 months after operation. The effective rate and excellent rate of the treatment group 1, 3 and 6 months after PCDN were higher than those of the control group (P<0.05). Follow-up to 1 year after surgery, no significant postoperative adverse reactions and complications were found in both groups.
    CONCLUSIONS: Ultrasound-guided acupotomy can significantly improve the residual symptoms after PCDN for CSR patients, and the clinical efficacy is significantly better than that of PCDN alone, and this therapy is safe and reliable.
    目的: 观察超声引导下针刀疗法辅助治疗神经根型颈椎病低温等离子髓核射频消融术(PCDN)术后残留症状的疗效及安全性。方法: 将70例神经根型颈椎病患者随机分为试验组和对照组,每组35例。对照组患者接受PCDN治疗。试验组患者在对照组基础上在PCDN术后第2天行超声引导下针刀治疗,每隔5~7 d进行1次,共行4~6次。分别于PCDN术前和术后1 d(针刀治疗前)及1、3、6个月时采用疼痛视觉模拟量尺(VAS)评分评价患者疼痛程度,采用颈部功能障碍指数(NDI)评分、日本骨科学会颈椎病(JOA)评分、田中靖久20分法量表评估患者颈椎病的严重程度,评估两组患者的临床疗效并计算治疗有效率和优良率,记录术后不良反应及并发症。结果: 与PCDN术前比较,术后1 d及1、3、6个月时两组患者的VAS评分和NDI评分均降低(P<0.05),JOA评分和田中靖久20分法评分均升高(P<0.05)。与术后1 d比较,试验组患者术后1、3、6个月时VAS评分和NDI评分均降低(P<0.05),JOA评分和田中靖久20分法评分均升高(P<0.05)。与同时点对照组比较,试验组术后1、3、6个月时VAS评分和NDI评分均降低(P<0.05),JOA评分和田中靖久20分法评分均升高(P<0.05)。试验组患者PCDN术后1、3、6个月时有效率和优良率均高于同时间点对照组(P<0.05)。随访至术后1年,两组患者均无明显术后不良反应及并发症。结论: 超声引导下针刀疗法可显著改善神经根型颈椎病PCDN后的残留症状,疗效明显优于单纯行PCDN手术,且安全可靠。.
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  • 文章类型: Journal Article
    目的:使用电子健康记录(EHR)开发和验证自然语言处理(NLP)驱动的人工智能(AI)模型,用于诊断腰椎间盘突出症(LDH)伴L5和S1神经根病。
    方法:收集2013年6月1日至2021年12月31日期间接受单级经皮内窥镜腰椎间盘切除术(PELD)治疗L4/5或L5/S1水平LDH的患者的EHR。主要结果是LDH伴L5和S1神经根病,定义为手术记录中记录的神经根受压。使用现病史(HPI)文本和神经根病(L5或S1)阳性症状(PS)文本创建数据集,分别。数据集以7:3的比例随机分为训练集和测试集。两种机器学习(ML)模型,长短期记忆(LSTM)网络和极端梯度提升(XGBoost),是使用训练集开发的。测试集上的模型的性能评估是使用测量,如接收器工作特性(ROC)曲线,曲线下面积(AUC),准确度,召回,F1分数,和精度。
    结果:该研究共包括1681名患者,590例L5神经根病患者和1091例S1神经根病患者。在开发的四个模型中,基于PS文本的LSTM模型在测试集中表现出最佳的区分度,精度(0.9054),召回(0.9405),精度(0.8950),F1分数(0.9226),和AUC(0.9485)。
    结论:这项研究提供了对NLP驱动的AI模型可用于使用EHR诊断腰椎疾病的概念的初步验证。这项研究可以为未来的研究铺平道路,这些研究可能会开发更全面和具有临床影响力的AI驱动诊断系统。
    OBJECTIVE: To develop and validate natural language processing-driven artificial intelligence (AI) models for the diagnosis of lumbar disc herniation (LDH) with L5 and S1 radiculopathy using electronic health records (EHRs).
    METHODS: EHRs of patients undergoing single-level percutaneous endoscopic lumbar discectomy for the treatment of LDH at the L4/5 or L5/S1 level between June 1, 2013, and December 31, 2021, were collected. The primary outcome was LDH with L5 and S1 radiculopathy, which was defined as nerve root compression recorded in the operative notes. Datasets were created using the history of present illness text and positive symptom text with radiculopathy (L5 or S1), respectively. The datasets were randomly split into a training set and a testing set in a 7:3 ratio. Two machine learning models, the long short-term memory network and Extreme Gradient Boosting, were developed using the training set. Performance evaluation of the models on the testing set was done using measures such as the receiver operating characteristic curve, area under the curve, accuracy, recall, F1-score, and precision.
    RESULTS: The study included a total of 1681 patients, with 590 patients having L5 radiculopathy and 1091 patients having S1 radiculopathy. Among the 4 models developed, the long short-term memory model based on positive symptom text showed the best discrimination in the testing set, with precision (0.9054), recall (0.9405), accuracy (0.8950), F1-score (0.9226), and area under the curve (0.9485).
    CONCLUSIONS: This study provides preliminary validation of the concept that natural language processing-driven AI models can be used for the diagnosis of lumbar disease using EHRs. This study could pave the way for future research that may develop more comprehensive and clinically impactful AI-driven diagnostic systems.
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