Optos

OPTOS
  • 文章类型: Journal Article
    背景:为了研究Optos成像对视力退化性肌脱视(VDM)的诊断敏感性。
    方法:本横断面研究共收集了345例VDM患者的420只眼。所有眼睛都被分类为有玻璃体后脱离(PVD)或没有PVD。评估了Optos成像对玻璃体漂浮物可见性的敏感性。在单变量和多变量逻辑回归分析中,分析了与Optos图像上玻璃体漂浮物可见性的相关因素。
    结果:所有患者的平均年龄为56.19±13.89岁,66.67%的患者为女性。在所有眼睛的超声B扫描上都可以看到玻璃体漂浮物,但仅在47.62%的Optos图像中(有PVD的眼睛为55.29%,无PVD的眼睛为15%)。在多元二元逻辑回归分析中,年龄(OR=1.094,95CI=1.063-1.125,P<0.001),球形当量(OR=0.869,95CI=0.791-0.955,P=0.004)和漂浮物与视网膜的距离(OR=1.191,95CI=1.059-1.339,P=0.003)与玻璃体漂浮物在Optos图像上的可见度显着相关。在Optos图像上,25.71%的VDM眼表现出额外的视网膜异常。
    结论:Optos成像对玻璃体漂浮物的敏感性较低,特别是没有PVD的眼睛。在Optos成像上,漂浮物在老年患者中更明显,近视较大的眼睛,和离视网膜更远的漂浮物。
    BACKGROUND: To investigate the diagnostic sensitivity of Optos imaging for vision degrading myodesopsia (VDM).
    METHODS: A total of 420 eyes from 345 patients with VDM were collected in this cross-sectional study. All eyes were classified as having posterior vitreous detachment (PVD) or not having PVD. The sensitivity of Optos imaging for the visibility of vitreous floaters was evaluated. The associated factors with the visibility of vitreous floaters on Optos images were analyzed in univariate and multivariate logistic regression analyses.
    RESULTS: The mean age of all patients was 56.19 ± 13.89 years old, and 66.67% of patients were female. The vitreous floaters were visible on the ultrasound B scan in all eyes, but only in 47.62% of Optos images (55.29% in eyes with PVD and 15% in eyes without PVD). In the multiple binary logistic regression analysis, age (OR = 1.094, 95%CI = 1.063-1.125, P < 0.001), spherical equivalent (OR = 0.869, 95%CI = 0.791-0.955, P = 0.004) and the distance of the floaters from the retina (OR = 1.191, 95%CI = 1.059-1.339, P = 0.003) were significantly correlated with the visibility of vitreous floaters on Optos images. On Optos images, 25.71% of VDM eyes presented additional retinal abnormalities.
    CONCLUSIONS: Optos imaging has a low sensitivity for vitreous floaters, particularly in eyes without PVD. On Optos imaging, floaters were more visible in older patients, eyes with greater myopia, and floaters that were further from the retina.
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  • 文章类型: Journal Article
    OBJECTIVE: This study aims to investigate the ability of the ultra-wide-field scanning laser ophthalmoscope (UWF SLO) in clinically detecting and evaluating asymptomatic early-stage familial exudative vitreoretinopathy (FEVR).
    METHODS: We retrospectively reviewed 163 eyes of 83 asymptomatic family members of 48 patients with FEVR. UWF SLO imaging (Optos® PLC, Scotland, UK) was performed on asymptomatic family members as a preliminary screening test for fundus anomalies, and the findings were compared with subsequent examinations using indirect fundus ophthalmoscopy in full mydriasis, fluorescein angiography (FA), fundus autoflourescence, and genetic sequencing.
    RESULTS: A total of 86 eyes of 43 asymptomatic family members were clinically diagnosed with early-stage FEVR, and 17 of the affected 43 family members were also genetically diagnosed. Compared with FA as a standard, the UWF SLO was highly effective in diagnosing FEVR with a sensitivity and specificity of 93.0 % and 97.5 %, respectively. The UWF SLO was able to diagnose early-stage FEVR in 93.0 % of eyes, and guided the selection of therapies in 46.5 % of the eyes studied.
    CONCLUSIONS: UWF SLO is a valuable imaging tool for detecting fundus anomalies related to early-stage FEVR, and this tool can assist in the clinical diagnosis and evaluation of early-stage FEVR in asymptomatic family members of patients with FEVR.
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