■嗜铬细胞瘤是一种罕见的产生儿茶酚胺的神经内分泌肿瘤,起源于肾上腺髓质或肾上腺旁神经节的嗜铬细胞。然而,关于嗜铬细胞瘤的文献计量学研究很少。因此,本研究通过文献计量分析总结嗜铬细胞瘤的全球趋势和现状。
■搜索了2001年至2021年与嗜铬细胞瘤有关的出版物。文献计量分析用于检查数据,微软Excel被用来创建条形图。此外,VOSviewer被用来进行共同作者分析,共引分析和共现分析。CiteSpace用于分析关键词引文爆发。
■我们的研究包括来自100个国家/地区的6,117个组织的38,590位作者在1,806种期刊上发表的8,653篇出版物。其中,就总出版物和引用时间而言,美国是领先的国家,而尤尼斯·肯尼迪·施莱弗·纳特·纳特·里斯特·希斯和哈姆是领先的机构。嗜铬细胞瘤相关文章的主要出版物是临床内分泌与代谢杂志。Pacakkarel和EisenhoferGraeme是主要撰稿人。嗜铬细胞瘤的研究可以分为五组:治疗,机制,病因学,放射学和激素研究。此外,放射学研究,病因学研究和一些特定的关键词,如种系突变,间充质干细胞,自噬,神经炎症,神经毒性,血流动力学不稳定,可能成为未来的热点。
■尽管在过去20年中,关于嗜铬细胞瘤的文章数量略有波动,总体呈上升趋势。总的来说,嗜铬细胞瘤的精准医学研究,尤其是转移性嗜铬细胞瘤,在诊断方面,治疗,病因学将是今后研究的热点。本研究有助于理解研究视角,嗜铬细胞瘤的研究热点和发展趋势,为今后嗜铬细胞瘤的研究提供新的见解和依据。
Pheochromocytoma is a rare catecholamine-producing neuroendocrine tumour originating from the chromaffin cells of the adrenal medulla or extra-adrenal paraganglia. However, there are few bibliometric studies on Pheochromocytoma. Therefore, this study was employed to summarize the global trends and current status in pheochromocytoma by bibliometric analysis.
The Web of Science (WOS) core collection database was searched for publications relating to pheochromocytoma from 2001 to 2021. Bibliometric analysis was used to examine the data, and Microsoft Excel was utilized to create bar graphs. In addition, VOSviewer was used to carry out co-authorship analysis, co-citation analysis and co-occurrence analysis. CiteSpace was used to analyze the keywords citation bursts.
A total of 8,653 publications published in 1,806 journals by 38,590 authors in 6,117 organizations from 100 countries/regions were included in our study. Among them, USA was the leading countries in terms of total publications and sum of time cited, whereas Eunice Kennedy Shriver Natl Inst Child Hlth & Hum was the leading institutions. The main publications for pheochromocytoma-related articles were Journal of clinical endocrinology &metabolism. Pacak karel and Eisenhofer Graeme were the main contributing authors. The studies on pheochromocytoma could be grouped into five clusters: Treatment, Mechanism, Etiology, Radiology and Hormones study. Moreover, the radiology study, etiology study and some specific keywords such germlines mutation, mesenchymal stem-cells, autophagy, neuroinflammation, neurotoxicity, and hemodynamic instability, may become the hot spots of future.
Although the number of articles on pheochromocytoma has fluctuated slightly over the past 20 years, there has been an overall upward trend. In general, precision medicine research on pheochromocytoma, especially metastatic pheochromocytoma, in terms of diagnosis, treatment, and etiology will be a hot research topic in the future. This study helps to understand the research perspectives, hot spots and trends of pheochromocytoma and provide new insight and a basis for future pheochromocytoma research quickly.