背景:稳定的地磁场和不稳定的地磁活动与死亡率之间的相关性,发病率,和心血管疾病(CVD)的患病率仍然模棱两可。
方法:为了研究全球地磁场(GMF)强度与地磁扰动(GMD)和CVD事件之间的相关性,长周期尺度,根据2019年全球疾病负担研究(GBD2019),纳入了全球和204个国家和地区。GMF强度数据,GMD频率,CVD事件,收集了1996年至2019年所包括地点的天气和卫生经济指标。进行线性回归和面板数据建模以确定GMF强度和CVD事件之间的相关性。还进行了多因素面板数据分析,以调整混杂因素的影响。
结果:对于1996-2019年的平均数据,线性回归模型显示总GMF(tGMF)强度与总CVD死亡率之间存在一致的正相关关系[系数=0.009,(0.006,0.01195CI)],而水平GMF(hGMF)强度与心血管疾病总死亡率呈负相关[coef=-0.010(-0.013,-0.00795CI)].当考虑时间趋势时,面板数据分析仍显示tGMF与总CVD死亡率呈正相关[coef=0.009,(0.008,0.00995CI)]。同时,hGMF与总CVD死亡率呈负相关[coef=-0.008,(-0.009,-0.00795CI)]。当面板模型针对混杂因素进行调整时,tGMF之间没有发现相反的相关趋势,hGMF和CVD事件。在高收入地区,发现地磁风暴(GMS)频率与总CVD死亡率之间存在正相关[coef=14.007,(2.785,25.22995CI)],然而,随着纬度从极地到赤道的减少,这种积极趋势逐渐消失。
结论:GMF的稳定和长期水平成分可能对心脏健康有益。称为GMD的不稳定和短期GMF可能会危害心脏健康。我们的结果表明,定期GMF在维持心脏健康状态中的重要性以及GMD对心脏健康的不利影响。
The correlation between stable geomagnetic fields and unstable geomagnetic activities with mortality, incidence, and prevalence of cardiovascular diseases (CVDs) remains ambiguous.
To investigate the correlations between geomagnetic field (GMF) intensity and geomagnetic disturbance (GMD) and CVDs events in global, long-period scale, global and 204 countries and territories were included on the base of 2019 Global Burden of Disease study (GBD 2019). Data of GMF intensity, GMD frequency, CVDs events, weather and health economic indicators from 1996 to 2019 of included locations were collected. Linear regression and panel data modelling were conducted to identify the correlations between GMF intensity and CVDs events, multi-factor panel data analysis was also generated to adjust the effect of confounding factors.
For the average data during 1996-2019, linear regression model revealed consistent positive correlations between total GMF (tGMF) intensity and mortality of total CVDs [coef = 0.009, (0.006,0.011 95%CI)], whereas negative correlations were found between horizonal GMF (hGMF) intensity and total CVD mortality [coef = -0.010 (-0.013, -0.007 95%CI)]. When considering the time trend, panel data analysis still demonstrated positive correlation between tGMF and total CVDs mortality [coef = 0.009, (0.008,0.009 95%CI)]. Concurrently, the hGMF negatively correlated with total CVDs mortality [coef = -0.008, (-0.009, -0.007 95%CI)]. When the panel models were adjusted for confounding factors, no reverse of correlation tendency was found between tGMF, hGMF and CVDs events. In high-income territories, positive correlation was found between geomagnetic storm (GMS) frequency and mortality of total CVDs [coef = 14.007,(2.785, 25.229 95%CI)], however, this positive trend faded away gradually with the latitude decreasing from polar to equator.
Stable and long-term horizontal component of GMF may be beneficial to cardiac health. Unstable and short-term GMF called GMD could be a hazard to cardiac health. Our results suggest the importance of regular GMF in maintaining cardio-health state and the adverse impacts of GMD on cardiac health.