背景:发生在脚底上的疣被称为足底疣,其中大多数可以反复复发,很难根除。肥厚性和难治性足底疣常伴有疼痛和不适,这给患者的日常生活带来了许多不便。
目的:本研究旨在分析浅表放疗(SRT-100)治疗难治性足底疣的疗效,为后续治疗该病的高复发率创造有利条件。
方法:对2023年1月至6月在我院门诊接受浅表放疗治疗的难治性足底疣进行回顾性分析。
结果:本研究共纳入30例患者(中位年龄,33年)。男女比例为1:3.29。放疗后两到六个月,23名(76.67%)患者的疣全部消退,大部分疣在4名(13.33%)患者中消退,3(10%)患者对治疗无反应,7例(23.33%)患者在疣消退后复发或新发疣。
结论:大多数难治性足底疣患者经过浅层放疗后好转。我们的研究表明,男性比女性更容易患足底疣,中青年是受该病影响的主要人群。浅层放疗是治疗难治性足底疣的有效方法,可以在短时间内迅速清除疣。它既安全又无创,不良反应最小。部分患者病灶清除后复发,浅表放疗可以为病毒性疣的后续临床治疗创造有利条件。
BACKGROUND: Verrucas that occur on the soles of the feet are called plantar warts, most of which can recur repeatedly and are difficult to eradicate. Hypertrophic and refractory plantar warts are often accompanied by pain and discomfort, which cause many inconveniences in patients\' daily lives.
OBJECTIVE: This study aimed to analyze the therapeutic effect of superficial radiotherapy (SRT-100) on refractory plantar warts and further create favorable conditions for the subsequent treatment of this disease with a high recurrence rate.
METHODS: A retrospective analysis was conducted for refractory plantar warts treated with superficial radiotherapy in our outpatient department from January to June 2023.
RESULTS: A total of 30 patients were included in our study (median age, 33 years). The female-to-male ratio was 1:3.29. Two to six months after radiotherapy, all of the warts subsided in 23 (76.67%) patients, most of the warts subsided in 4 (13.33%) patients, 3 (10%) patients did not respond to treatment, and 7 (23.33%) patients had recurrent or new warts after their warts subsided.
CONCLUSIONS: Most patients with refractory plantar warts improved after superficial radiotherapy. Our study presented that men are more susceptible to plantar warts than women, and young and middle-aged people are the main population affected by the disease. Superficial radiotherapy is an effective treatment for refractory plantar warts, which can quickly remove the warts in a short period. It is safe and noninvasive, with minimal adverse reactions. Some patients relapse after the lesion is clear, and superficial radiotherapy can create favorable conditions for the subsequent treatment of viral warts in clinical practice.