这篇综述和荟萃分析旨在评估高强度间歇训练(HIIT)与常规护理(UC)或中等强度训练(MIE)相比对癌症患者在所有阶段的身体健康和健康相关结果的影响治疗和护理。
根据PRISMA指南对数据库进行了系统搜索,直到10月4日,2018.合格标准包括各种癌症类型的成年患者,执行HIIT与UC或MIE。感兴趣的结果包括身体健康(心肺健康[VO2peak]和功能能力)和与健康相关的结果(身体成分,生活质量,癌症相关的疲劳,和血液传播的生物标志物)。计算平均差(MD)并合并以产生VO2峰的效应大小。
搜索确定了1453项研究,其中包括12篇文章。平均干预时间为6.7±3.0周,每周2.8±0.5次。对VO2peak的荟萃分析显示,HIIT优于UC(MD3.73;95%CI2.07,5.39;p<0.001),但不优于MIE(MD1.36;95%CI-1.62,4.35;p=0.370)。同样,与MIE相比,HIIT在生活质量或瘦体重变化方面没有发现更好的效果,虽然有证据表明脂肪量有更大的减少。
这项系统评价显示,短期HIIT对身体健康和健康相关结果的积极影响与MIE相似,但似乎优于UC。因此,HIIT可能是癌症患者在治疗和善后护理的所有阶段的时间有效干预。
高强度间歇训练(HIIT)在改善癌症患者在治疗和善后护理的各个阶段的身体健康和与健康相关的结果方面优于usupal护理。目前,与中等强度有氧训练(MIE)相比,没有证据表明HIIT对心肺适应性变化的益处,瘦体重和患者报告的结果。当在后期护理中进行训练时,与MIE相比,HIIT中脂肪量的减少可能更明显。
This review and meta-analysis aimed to evaluate the effects of high-intensity interval training (HIIT) compared to usual care (UC) or moderate-intensity training (MIE) on physical fitness and health-related outcomes in cancer patients across all stages of therapy and aftercare.
Databases were systematically searched in accordance with the PRISMA guidelines until October 4th, 2018. Eligibility criteria included adult patients of various cancer types, performing HIIT vs. UC or MIE. Outcomes of interest included physical fitness (cardiorespiratory fitness [VO2peak] and functional capacity) and health-related outcomes (body composition, quality of life, cancer-related fatigue, and blood-borne biomarkers). Mean differences (MD) were calculated and pooled to generate effect sizes for VO2peak.
The search identified 1453 studies, out of which 12 articles were included. The average duration of interventions was 6.7 ± 3.0 weeks, with 2.8 ± 0.5 sessions per week. The meta-analysis for VO2peak showed superiority of HIIT compared to UC (MD 3.73; 95% CI 2.07, 5.39; p < 0.001) but not MIE (MD 1.36; 95% CI - 1.62, 4.35; p = 0.370). Similarly, no superior effects of HIIT compared to MIE were found for quality of life or changes in lean mass, while evidence was provided for a larger reduction in fat mass.
This systematic review showed that short-term HIIT induces similar positive effects on physical fitness and health-related outcomes as MIE but seems to be superior compared to UC. Thus, HIIT might be a time-efficient intervention for cancer patients across all stages of therapy and aftercare.
High-intensity interval training (HIIT) is superior compared to usucal care in improving physical fitness and health-related outcomes in cancer patients across all stages of therapy and aftercare. Currently, there is no evidence for the benefits of HIIT compared to aerobic training of moderate intensity (MIE) for changes in cardiorespiratory fitness, lean mass and patient-reported outcomes. Reductions in fat mass may be more pronounced in HIIT compared to MIE when training is performed in aftercare.