目的:本研究评估MS患者睡眠障碍的存在及其与临床和人口统计学变量的关系,以建立不同变量与睡眠障碍频率之间的相关性。
方法:采用匹兹堡睡眠质量指数(PSQI)检测睡眠障碍。我们联系了在MS病房接受治疗的患者,并向221名患者分发了问卷(PSQI),在2019年9月8日至30日之间收到142份可用问卷。
结果:我们研究中睡眠障碍患者的患病率为74.7%(女性为73.7%,男性为76.8%)。因此,睡眠障碍在MS患者中普遍存在,4个病人中有3个经历过这些,高于在没有疾病的人群中观察到的比率。睡眠障碍的频率随着年龄的增长而逐渐增加。在分析的两个年龄组中,44-54岁和55-68岁,中度和重度睡眠障碍的比例分别为42.8%和53.9%,分别。27.5%的人观察到中度和重度睡眠障碍,44.7%,58.3%的扩展残疾状态量表评分分别为0-3、3-6和>6。
结论:我们的结果表明,睡眠障碍在MS患者中比在其他人群中更常见。患有继发性进行性MS的患者更频繁地表现出睡眠障碍,而原发性进展形式的患者报告频率较低。年龄和残疾程度与MS患者睡眠障碍的患病率和严重程度呈正相关。
OBJECTIVE: This study assesses the presence of sleep disturbances and their relationship with clinical and demographic variables in patients with MS, with a view to establishing correlations between the different variables and the frequency of sleep disturbances.
METHODS: The Pittsburgh Sleep Quality Index (PSQI) was used to detect sleep disorders. We contacted patients treated at the MS unit and distributed a questionnaire (PSQI) to 221 patients, receiving 142 usable questionnaires between 8 and 30 September 2019.
RESULTS: The prevalence of patients with sleep disturbances in our study was 74.7% (73.7% in women and 76.8% in men). Therefore, sleep disorders are pervasive in patients with MS, with 3 out of 4 patients experiencing them, a higher rate than that observed in the population without the disease. The frequency of sleep disorders gradually increased in line with age. In the 2 age groups analyzed, 44-54 years and 55-68 years, the proportion of moderate and severe sleep disorders was 42.8% and 53.9%, respectively. Moderate and severe sleep disturbances were observed in 27.5%, 44.7%, and 58.3% of patients with Expanded Disability Status Scale scores of 0-3, 3-6, and >6, respectively.
CONCLUSIONS: Our results indicate that sleep disorders are more common in patients with MS than in other populations. Patients with secondary progressive forms of MS more frequently present sleep disturbances, while patients with primary progressive forms report them less frequently. Age and degree of disability were positively correlated with the prevalence and severity of sleep disorders in MS patients.