回顾性回顾Erdheim-Chester病患者的计算机断层扫描(CT)成像中的非典型骨发现。
所有28例Erdheim-Chester病患者(13例男性和15例女性;平均年龄,45年;范围,7-63岁)接受了胸腹部骨盆CT检查。两位放射科医生一致回顾并分析了CT图像中非典型骨病变的各种特征。
21例患者有不典型骨受累。放射学上,这些非典型骨病变分为三种类型:弥漫性,结节状和斑片状。21例患者中有11例(52%)有脊柱病变,其中四个(36%)为弥漫型,八位(73%)有结节样,和6(55%)有斑驳的模式。21例患者中有16例(76%)有盆腔受累,其中两个(13%)是弥漫性的,9例(56%)为结节状,11例(69%)为斑片状。21名患者中有7名(33%)涉及肋骨,1例(14%)患者呈结节状,6例(86%)患者呈斑片状。21例患者中有9例(43%)出现锁骨受累,其中弥漫性类型仅在一名(11%)患者中发现,6例(67%)患者的结节型,4例(44%)患者为单发斑片型。在21例患者中,有10例(48%)出现胸骨受累,并且均为结节状。
本系列提供了Erdheim-Chester病中非典型骨受累的详细描述,在CT上显示三种主要模式。了解这些模式可能有助于提高诊断这种疾病的准确性。
To review retrospectively atypical bone findings from computed tomographic (CT) imaging in patients with Erdheim-Chester disease.
All 28 patients with Erdheim-Chester disease (13 men and 15 women; mean age, 45 years; range, 7-63 years) underwent chest-abdomen-pelvis CT. CT images were reviewed and analyzed for the various features of atypical bone lesions by two radiologists in consensus.
Twenty-one patients had atypical bone involvement. Radiologically, these atypical osseous lesions were categorized into three types: diffuse, nodular and patchy. Eleven (52%) of the 21 patients had spinal lesions, of which four (36%) had the diffuse type, eight (73%) had the nodular pattern, and six (55%) had the patchy pattern. Sixteen (76%) of the 21 patients had pelvic involvement, of which two (13%) were diffuse, nine (56%) were nodular and 11 were (69%) patchy. Ribs were involved in seven (33%) of the 21 patients, with the nodular pattern in one (14%) patient and the patchy type in six (86%) patients. Clavicle involvement was seen in nine (43%) of the 21 patients, of which the diffuse type was found in only one (11%) patient, the nodular type in six (67%) patients, the solitary patchy type in four (44%) patients. Sternum involvement was seen in 10 (48%) of the 21 patients and all were nodular.
This series provides a detailed description of atypical bone involvement in Erdheim-Chester disease which on CT displays three major patterns. Understanding these patterns may help increase the accuracy of diagnosis of this disease.