Data

Data
  • 文章类型: Journal Article
    越来越多的关于使用雷达的非接触式生命体征检测的研究现在开始转向数据驱动的神经网络方法,而不是传统的信号处理方法。然而,由于难以获取和标记数据,因此很少有雷达数据集可用于深度学习,这需要专门的设备和医生的合作。本文提出了一种新的心跳诱发胸壁运动(CWM)模型,其目标是生成大量模拟数据以支持深度学习方法。对VICON红外(IR)运动捕获系统和连续波(CW)雷达系统在保持呼吸期间收集的已发布的CWM数据进行了深入分析,以总结心动周期内每个阶段的运动特征。结合心跳的生理特性,选择适当的数学函数来描述这些运动特性。该模型产生的模拟数据与通过动态时间规整(DTW)和均方根误差(RMSE)评估的测量数据紧密匹配。通过调整模型参数,模拟不同个体的心跳信号。这将加速数据驱动的深度学习方法在基于雷达的非接触式生命体征检测研究中的应用,并进一步推进该领域。
    An increasing number of studies on non-contact vital sign detection using radar are now beginning to turn to data-driven neural network approaches rather than traditional signal-processing methods. However, there are few radar datasets available for deep learning due to the difficulty of acquiring and labeling the data, which require specialized equipment and physician collaboration. This paper presents a new model of heartbeat-induced chest wall motion (CWM) with the goal of generating a large amount of simulation data to support deep learning methods. An in-depth analysis of published CWM data collected by the VICON Infrared (IR) motion capture system and continuous wave (CW) radar system during respiratory hold was used to summarize the motion characteristics of each stage within a cardiac cycle. In combination with the physiological properties of the heartbeat, appropriate mathematical functions were selected to describe these movement properties. The model produced simulation data that closely matched the measured data as evaluated by dynamic time warping (DTW) and the root-mean-squared error (RMSE). By adjusting the model parameters, the heartbeat signals of different individuals were simulated. This will accelerate the application of data-driven deep learning methods in radar-based non-contact vital sign detection research and further advance the field.
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  • 文章类型: Journal Article
    目的:本研究的目的是调查45岁以上普通人群炎症负担指数(IBI)与全因死亡率之间的关系。
    结果:该研究包括来自国家健康和检查营养调查(NHANES)的8827名年龄超过45岁的参与者。IBI使用三个标志物计算:C反应蛋白×中性粒细胞/淋巴细胞,将所有参与者分为四组(四分位数1:IBI≤0.178,N=2206;四分位数2:0.1781.099,2207)。Cox比例风险回归模型用于估计IBI与全因死亡率之间的关联的风险比(HR)和95%置信区间(CI)。在129个月的中位随访中,2431人死亡。1号、2号、3号和4号四分位全因死亡率为14.76%,17.67%,23.18%和29.69%,分别(p<0.001)。在人口统计调整后,和潜在的临床因素,较高的IBI与全因死亡率风险增加显著相关(四分位数3与四分位数1:HR=1.26,95%CI:1.08至1.46,p=0.003;四分位数4与四分位数1:HR=1.59,95%CI:1.40至1.80,p<0.001)。此外,受限三次样条分析的结果表明,IBI和全因死亡率之间的关联是非线性的和正的,没有特定的阈值。
    结论:这项研究支持,在45岁以上的普通人群中,较高的IBI与全因死亡风险增加相关。
    OBJECTIVE: The objective of this study was to investigate the association between inflammatory burden index (IBI) and all-cause mortality in the general population aged over 45 years.
    RESULTS: The study included 8827 participants from the National Health and Examination Nutrition Survey (NHANES) who were aged over 45 years. The IBI was calculated using three markers: C-reaction protein × neutrophil/lymphocyte, and all the participants were classified into four groups (Quartile 1: IBI ≤0.178, N = 2206; Quartile 2: 0.178 1.099, 2207). Cox proportional hazards regression models were used to estimate hazard ratios (HR) and 95 % confidence interval (CI) for the association between IBI and all-cause mortality. During a median follow-up of 129 month, 2431 deaths occurred. The all-cause mortality rate in Quartile 1, Quartile 2, Quartile 3 and Quartile 4 was 14.76 %, 17.67 %, 23.18 % and 29.69 %, respectively (p < 0.001). After adjustment for demographic, and potential clinical factors, higher IBI was significantly associated with an increased risk of all-cause mortality (Quartile 3 vs. Quartile 1: HR = 1.26, 95 % CI: 1.08 to 1.46, p = 0.003; Quartile 4 vs. Quartile 1: HR = 1.59, 95 % CI: 1.40 to 1.80, p < 0.001). Furthermore, the results of the restricted cubic spline analysis suggested that the association between IBI and all-cause mortality was nonlinear and positive, without specific threshold value.
    CONCLUSIONS: This study supports that higher IBI is associated with an increased risk of all-cause mortality in the general population aged over 45 years.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    背景:近年来,人工智能(AI)技术得到了显着发展。医疗人工智能的公平性因其与人类生命和健康的直接关系而备受关注。这篇综述旨在从计算机科学的角度分析现有的关于医学人工智能公平性的研究文献,医学科学,和社会科学(包括法律和伦理学)。检讨的目的,是研究对公平的理解的异同,探索影响因素,并研究在英汉文献中实施医学人工智能公平性的潜在措施。
    方法:本研究采用了范围审查方法,并选择了以下数据库:WebofScience,MEDLINE,Pubmed,OVID,CNKI,万方数据,等。,到2023年2月,医疗人工智能的公平性问题。搜索是使用各种关键字进行的,例如“人工智能,\"\"机器学习,\"\"医学,\"\"算法,\"\"公平,\"\"决策,“和”偏见。“收集的数据被绘制出来,合成,并进行描述性和主题分析。
    结果:在审阅了468篇英文论文和356篇中文论文之后,53和42包括在最终分析中。我们的结果表明,三个不同的学科在核心问题的研究上都表现出显著的差异。除了算法偏差和人为偏差之外,数据是影响医疗AI公平性的基础。Legal,伦理,和技术措施都促进了医疗AI公平的实施。
    结论:我们的综述表明,关于数据公平性作为跨多学科视角实现医学AI公平性的基础的重要性,达成了共识。然而,在概念、影响因素,以及医疗人工智能公平性的实施措施。因此,未来的研究应该促进跨学科的讨论,以弥合不同领域之间的认知差距,并加强医疗人工智能中公平性的实际实施。
    Artificial Intelligence (AI) technology has been developed significantly in recent years. The fairness of medical AI is of great concern due to its direct relation to human life and health. This review aims to analyze the existing research literature on fairness in medical AI from the perspectives of computer science, medical science, and social science (including law and ethics). The objective of the review is to examine the similarities and differences in the understanding of fairness, explore influencing factors, and investigate potential measures to implement fairness in medical AI across English and Chinese literature.
    This study employed a scoping review methodology and selected the following databases: Web of Science, MEDLINE, Pubmed, OVID, CNKI, WANFANG Data, etc., for the fairness issues in medical AI through February 2023. The search was conducted using various keywords such as \"artificial intelligence,\" \"machine learning,\" \"medical,\" \"algorithm,\" \"fairness,\" \"decision-making,\" and \"bias.\" The collected data were charted, synthesized, and subjected to descriptive and thematic analysis.
    After reviewing 468 English papers and 356 Chinese papers, 53 and 42 were included in the final analysis. Our results show the three different disciplines all show significant differences in the research on the core issues. Data is the foundation that affects medical AI fairness in addition to algorithmic bias and human bias. Legal, ethical, and technological measures all promote the implementation of medical AI fairness.
    Our review indicates a consensus regarding the importance of data fairness as the foundation for achieving fairness in medical AI across multidisciplinary perspectives. However, there are substantial discrepancies in core aspects such as the concept, influencing factors, and implementation measures of fairness in medical AI. Consequently, future research should facilitate interdisciplinary discussions to bridge the cognitive gaps between different fields and enhance the practical implementation of fairness in medical AI.
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  • 文章类型: Journal Article
    随着近期昆明-蒙特利尔全球生物多样性框架(GBF)的启动,和相关的监测框架,了解支持它所需的框架和数据至关重要。不幸的是,虽然监测框架旨在提供关键数据,以监测实现目标和指标的进展,大多数指标对于检测或标记进度太不清楚。此任务最常见的数据集,比如世界自然保护联盟的物种名单,有很大的空间不准确,缺乏跟踪进展的时间分辨率,虽然基于点的数据集缺乏来自许多地区的数据,除了物种覆盖。利用现有数据将需要仔细使用现有数据,例如使用库存和预测丰富度模式,或在开发物种级模型和评估之前填补数据空白。由于高分辨率数据超出了监测框架内明确指标的范围,使用GEOBON内的基本生物多样性变量(在监测框架的前奏中指出)作为数据汇总的工具,提供了一种整理必要的高分辨率数据的机制。最终制定有效的保护目标将需要更好的物种数据,为此,国家生物多样性战略行动计划(NBSAP)和新的数据动员机制将是必要的。此外,利用气候目标和GBF内的气候生物多样性协同作用为制定有意义的目标提供了额外的手段,试图开发迫切需要的数据来监测生物多样性趋势,优先考虑有意义的任务,并跟踪我们在实现生物多样性目标方面的进展。
    With the recent launch of the Kunming-Montreal global biodiversity framework (GBF), and the associated monitoring framework, understanding the framework and data needed to support it is crucial. Unfortunately, whilst the monitoring framework was meant to provide key data to monitor progress towards goals and targets, most indicators are too unclear for detection or marking progress. The most common datasets for this task, such as the IUCN redlist of species, have major spatial inaccuracies, and lack the temporal resolution to track progress, whilst point-based datasets lack data from many regions, in addition to species coverage. Utilising existing data will require the careful use of existing data, such as the use of inventories and projecting richness patterns, or filling data gaps before developing species-level models and assessments. As high-resolution data fall outside the scope of explicit indicators within the monitoring framework, using essential biodiversity variables within GEOBON (which are noted in the prelude of the monitoring framework) as a vehicle for data aggregation provides a mechanism for collating the necessary high-resolution data. Ultimately developing effective targets for conservation will require better species data, for which National Biodiversity Strategic Action Plans (NBSAPs) and novel mechanisms for data mobilisation will be necessary. Furthermore, capitalising on climate targets and climate biodiversity synergies within the GBF provides an additional means for developing meaningful targets, trying to develop urgently needed data to monitor biodiversity trends, prioritising meaningful tasks, and tracking our progress towards biodiversity targets.
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  • 文章类型: Journal Article
    尽管有大量的数据和复杂的计算能力,大科技已经发展成为数据时代政府必须接受的新数据主权。数据挖掘和应用决定了数据的真正价值;在这方面,大技术很难取代。所谓的“第四次工业革命”正在重塑新兴的全球秩序,其核心是大型科技公司。他们不仅表达关切,传播价值观和意识形态,而且在国际事务中表现出强大的影响力,大科技似乎正在转变为一种新型的利维坦。通过访问大量数据,大科技的崛起对主权的排他性和优越性提出了挑战,假设事实上的数据主权地位。文章认为,大型科技公司,凭借其技术优势,不仅解构了传统的主权概念,而且还形成了复杂的共生关系。
    Despite the massive amount of data and sophisticated computing capacity, Big Tech has evolved into the new data sovereigns that governments must accept in the data era. Data mining and application determine the true value of data; in this regard, Big Tech is tough to replace. The so-called \"Fourth Industrial Revolution\" is reshaping the emerging global order, and at its core are Big Tech firms. They not only express their concerns and spread their values and ideologies but also make their strong presence felt in international affairs, as Big Tech appears to be transforming into a new type of Leviathan. With access to significant amounts of data, the rise of Big Tech poses a challenge to sovereignty\'s exclusivity and superiority, assuming the position of de facto data sovereign. The article holds that the Big Tech firms, by virtue of their technical advantages, have not only deconstructed the traditional concept of sovereignty, but also formed a complex symbiotic relationship.
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  • 文章类型: Journal Article
    目的:根据患者状况的变化确定重症监护病房发生压力性损伤的风险。
    方法:本回顾性研究基于二次数据分析。
    方法:回顾性地从电子健康记录中获得患者数据,我们包括438例和1752例有和没有压力损伤的患者,分别,在2017年1月至2020年2月期间入住内科和外科重症监护病房(ICU)的患者中.根据从ICU入院当天到压力性损伤发作前一天的第一个和最后一个客观数据值分析患者状况的变化,并分类如下:改善,保持正常,加剧和不变。基于11个变量进行Logistic回归以确定压力损伤发展的重要预测因素。
    结果:选择的11个变量是年龄,身体质量指数,活动,急性生理和慢性健康评估II评分,护理严重程度,脉搏和白蛋白,血细胞比容,C反应蛋白,总胆红素和血尿素氮水平。随着护理严重程度的恶化或持续异常,压力性损伤的风险很高。白蛋白,血细胞比容,C反应蛋白,血尿素氮和脉搏>100搏动/分钟。
    结论:定期监测血液学变量对于预防重症监护病房的压力性损伤很重要。
    这项研究遵循了STROBE指南。
    这项研究有助于利用电子健康记录中的患者数据。
    结论:除了其他压力伤害风险评估工具,ICU护士可以通过评估患者的血液检查结果来帮助预防压力伤害,从而促进患者安全和提高护理实践的有效性。
    OBJECTIVE: To determine the risk of pressure injury development in the intensive care unit based on changes in patient conditions.
    METHODS: This retrospective study was based on secondary data analysis.
    METHODS: Patient data from electronic health records were retrospectively obtained and we included 438 and 1752 patients with and without pressure injury, respectively, among those admitted to the medical and surgical intensive care units (ICUs) from January 2017-February 2020. Changes in patient conditions were analysed based on the first and last objective data values from the day of ICU admission to the day before the onset of pressure injury and categorised as follows: improved, maintained normal, exacerbated and unchanged. Logistic regression was performed to identify the significant predictors of pressure injury development based on 11 variables.
    RESULTS: The 11 selected variables were age, body mass index, activity, acute physiology and chronic health evaluation II score, nursing severity level, pulse and albumin, haematocrit, C-reactive protein, total bilirubin and blood urea nitrogen levels. The risk for a pressure injury was high with exacerbation of or persistently abnormal levels of nursing severity, albumin, haematocrit, C-reactive protein, blood urea nitrogen and pulse >100 beat/min.
    CONCLUSIONS: Periodic monitoring of haematological variables is important for preventing pressure injury in the intensive care unit.
    UNASSIGNED: The study followed STROBE guidelines.
    UNASSIGNED: This study contributes to the utilisation of patient data from electronic health records.
    CONCLUSIONS: In addition to other pressure injury risk assessment tools, ICU nurses can help prevent pressure injuries by assessing patients\' blood test results, thereby promoting patient safety and enhancing the efficacy of nursing practice.
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  • 文章类型: Journal Article
    BACKGROUND: In this paper, a semiautomatic image segmentation method for the serialized body slices of the Visible Human Project (VHP) is proposed.
    METHODS: In our method, we first verified the effectiveness of the shared matting method for the VHP slices and utilized it to segment a single image. Then, to meet the need for the automatic segmentation of serialized slice images, a method based on the parallel refinement method and flood-fill method was designed. The ROI (region of interest) image of the next slice can be extracted by using the skeleton image of the ROI in the current slice.
    RESULTS: Utilizing this strategy, the color slice images of the Visible Human body can be continuously and serially segmented. This method is not complex but is rapid and automatic with less manual participation.
    CONCLUSIONS: The experimental results show that the primary organs of the Visible Human body can be accurately extracted.
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  • 文章类型: Journal Article
    背景:性传播疾病(STDs)是世界范围内的严重问题。随着互联网的普及,在线健康信息寻求行为(OHISB)已被广泛采用,以改善健康和预防疾病。
    目的:本研究旨在探讨不同类型的OHISBs对性病的短期和长期影响,包括梅毒,淋病,和艾滋病由于艾滋病毒,基于百度指数。
    方法:收集多源大数据,包括性病的病例数,基于百度指数的搜索查询,省总人口,男女比例,65岁以上的人口比例,地区国内生产总值(GRDP),和2011-2018年中国大陆医疗机构数量数据。我们将OHISB分为4种类型:概念,症状,治疗,和预防。在控制社会经济和医疗状况之前和之后,我们应用多元线性回归分析了百度搜索指数(BSI)与百度搜索率(BSR)和性病病例数之间的关联.此外,我们比较了4种OHISB的效应,并进行了时滞交叉相关分析,以研究OHISB的长期效应.
    结果:STD病例数和OHISB的分布呈现变异性。对于案例编号,梅毒,和淋病,病例主要分布在中国东南和西北地区,而艾滋病毒/艾滋病病例大多分布在西南地区。对于搜索查询,东部地区的BSI和BSR最高,而西部地区是最低的。对于4种OHISB的3种疾病,BSI与病例数呈正相关,而BSR与病例数呈显著负相关(P<0.05)。不同类别的OHISB对性病病例数的影响不同。寻找预防往往会产生更大的影响,而寻求治疗的影响往往较小。此外,由于时滞效应,这些影响会随着时间的推移而增加。
    结论:我们的研究验证了4种OHISB类型与性病病例数之间的显著关联,随着时间的推移,OHISBs对性病的影响越来越强。它可以提供有关如何使用互联网大数据来更好地实现疾病监测和预防目标的见解。
    Sexually transmitted diseases (STDs) are a serious issue worldwide. With the popularity of the internet, online health information-seeking behavior (OHISB) has been widely adopted to improve health and prevent disease.
    This study aimed to investigate the short-term and long-term effects of different types of OHISBs on STDs, including syphilis, gonorrhea, and AIDS due to HIV, based on the Baidu index.
    Multisource big data were collected, including case numbers of STDs, search queries based on the Baidu index, provincial total population, male-female ratio, the proportion of the population older than 65 years, gross regional domestic product (GRDP), and health institution number data in 2011-2018 in mainland China. We categorized OHISBs into 4 types: concept, symptoms, treatment, and prevention. Before and after controlling for socioeconomic and medical conditions, we applied multiple linear regression to analyze associations between the Baidu search index (BSI) and Baidu search rate (BSR) and STD case numbers. In addition, we compared the effects of 4 types of OHISBs and performed time lag cross-correlation analyses to investigate the long-term effect of OHISB.
    The distributions of both STD case numbers and OHISBs presented variability. For case number, syphilis, and gonorrhea, cases were mainly distributed in southeastern and northwestern areas of China, while HIV/AIDS cases were mostly distributed in southwestern areas. For the search query, the eastern region had the highest BSI and BSR, while the western region had the lowest ones. For 4 types of OHISB for 3 diseases, the BSI was positively related to the case number, while the BSR was significantly negatively related to the case number (P<.05). Different categories of OHISB have different effects on STD case numbers. Searches for prevention tended to have a larger impact, while searches for treatment tended to have a smaller impact. Besides, due to the time lag effect, those impacts would increase over time.
    Our study validated the significant associations between 4 types of OHISBs and STD case numbers, and the impact of OHISBs on STDs became stronger over time. It may provide insights into how to use internet big data to better achieve disease surveillance and prevention goals.
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  • 文章类型: Letter
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