背景:研究的目的是评估特性并提供壁切应力(WSS)和流动湍流(Tur)的正常值,基于健康成年人的超声矢量血流成像(VFlow),以及它们在颈动脉分叉中的关系。
方法:三段(颈内动脉和颈外动脉的初始段[IICA和IECA];颈总动脉远端段[DCCA])的最大和平均WSS和Tur值,在前壁和后壁,在56名健康成年人中成功获得,使用超声波V流功能。进一步探讨了平均WSS与Tur之间的关系。
结果:平均WSS值为0.71Pa,0.86Pa,和0.96Pa在IICA,IECA,和DCCA,分别(IICA<IECA<DCCA,p<0.05)。平均Tur值为13.85%,5.46%,和IICA的4.17%,IECA,和DCCA,分别(IICA>IECA>DCCA,p<0.05)。选择截止值(WSS=0.4Pa),WSS截止值&lt;0.4Pa组的Tur值显着高于WSS截止值≥0.4Pa组(p&lt;0.01)。
结论:WSS和Tur呈中度负相关,可用于颈动脉分叉的定量评估,并可作为临床研究中早期发现颈动脉粥样硬化的潜在双参数工具。
BACKGROUND: The aim of the study was to evaluate characteristics and provide the normal values of wall shear stress (WSS) and flow turbulence (Tur), and the relationship between them in the carotid bifurcation based on an ultrasound vector flow imaging (V Flow) in healthy adults.
METHODS: Max and mean WSS and Tur values at three segments (initial segments of internal and external carotid arteries [IICA and IECA]; distal segment of common carotid artery [DCCA]), both in anterior and posterior walls, were successfully obtained in 56 healthy adults, using ultrasound V Flow function. Relationship between mean WSS and Tur was further explored.
RESULTS: The mean WSS value was 0.71 Pa, 0.86 Pa, and 0.96 Pa at IICA, IECA, and DCCA, respectively (IICA < IECA < DCCA, p < 0.05). The mean Tur value was 13.85%, 5.46%, and 4.17% at IICA, IECA, and DCCA, respectively (IICA > IECA > DCCA, p < 0.05). A cutoff value (WSS = 0.4 Pa) was selected and Tur values were significantly higher in group with WSS cutoff value <0.4 Pa than group with WSS cutoff value ≥0.4 Pa (p < 0.01).
CONCLUSIONS: WSS and Tur are moderately negatively correlated, which can be used in the quantitative evaluation of carotid bifurcation and could be a potential dual-parameter tool in the clinical research for early detection of carotid atherosclerosis.