乙型肝炎和丙型肝炎是两种可能危及生命的肝病,感染率高。身体穿孔代表了一种逐渐流行的社会文化现象,这也是乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的潜在暴露方法。从统计学上对HBV和HCV传播的身体穿孔风险评估的研究得出的结论是矛盾的。系统分析身体穿孔与普通人群传播乙型肝炎病毒和丙型肝炎病毒的风险之间的关联。对当前的做法提出基于证据的建议,并唤醒公众对这种威胁健康的行为的认识。在2015年1月15日之前,进行了全面和高灵敏度的搜索策略,以详尽搜索相关研究(MEDLINE,EMBASE,万方,已发表文献的CNKI数据集,以及谷歌和谷歌学者的相关灰色文章)。两位作者确定了这篇综述的相关研究,抽象数据,并根据选择标准和质量评估标准独立和批判性地评估文献质量。赔率比(OR)和相应的95%置信区间(CI)用于估计与身体穿刺状态相关的HBV和HCV感染的风险。进行亚组分析和敏感性分析以检查异质性的来源并检验结果的鲁棒性。本系统综述共纳入40项研究(10项针对Hep-B,26对于Hep-C,4对于Hep-B和Hep-C),合并OR(95%CI)的身体穿刺和HBV/HCV传播之间的关联是1.80(1.18,2.75)和1.83(1.27,2.64),分别。亚组分析表明,与丙型肝炎感染相关的身体穿孔风险最高的是前足球和退伍军人,OR为4.63(2.65,8.10),而身体穿刺和乙型肝炎之间最强的关联是来自学生/社区的样本,OR为2.40(1.44,4.02)。目前的系统评价和荟萃分析表明,身体穿刺与HBV和HCV的传播显着相关,刺穿身体可能会增加感染的风险。这项研究的证据强烈建议应建立全面有效的计划,以提供更安全的穿刺实践。
Hepatitis B and hepatitis C are 2 types of potentially life-threatening liver diseases with high infection rate. Body piercing represents a progressively popular sociocultural phenomenon which is also a potential exposure approach for hepatitis B virus (HBV) and hepatitis C virus (HCV). Conclusions from those researches with statistically risk assessment of body piercing on HBV and HCV transmission are contradictory.Systematically analyze the association between body piercing and the risk of transmitting hepatitis B virus and hepatitis C virus for general population. Make evidence-based recommendations to the current practice and wake up public awareness of this health-threatening behavior.Comprehensive and high sensitivity search strategies were performed to exhaustively search related studies before 15 January 2015 (MEDLINE, EMBASE, WANFANG, CNKI datasets for published literatures, and Google and Google scholars for related grey articles). Two authors identified relevant studies for the review, abstracted data, and assessed literature quality independently and critically according to the selection criteria and quality assessment standard. Odds ratio (OR) and corresponding 95% confidence interval (CI) were used to estimate risk of HBV and HCV infection in relation to body piercing status. Subgroup analysis and sensitivity analysis were conducted to examine the source of heterogeneity and test the robust of the results.A total of 40 studies were included in this systematic review (10 for Hep-B, 26 for Hep-C, 4 for both Hep-B and Hep-C), the pooled OR (95% CI) for the association between body piercing and transmission of HBV/HCV is 1.80 (1.18, 2.75) and 1.83 (1.27, 2.64), respectively. Subgroup analysis suggested that highest risk of body piercing related to hepatitis C infection was for former soccer and veterans with OR of 4.63 (2.65, 8.10), while strongest association between body piercing and hepatitis B was for samples derived from students/community with OR of 2.40 (1.44, 4.02).The current systematic review and meta-analysis suggests that body piercing is significantly associated with the transmission of HBV as well as HCV, having body piercing probably can increase the risk of getting infected. Evidence from this study strongly recommends that comprehensive and effective programs should be established to provide safer piercing practice.