Autograft

自体移植物
  • 文章类型: Case Reports
    背景:任何原因造成的胆管损伤对患者来说都是灾难,对外科医生构成了重大的心理和技术挑战。使用肝圆韧带和胆囊皮瓣作为自体移植物在修复胆管损伤方面显示出有希望的结果。
    方法:本文介绍了一个具有挑战性的Mirizzi综合征患者,该患者在胆囊切除术中经历了复杂的胆管缺损和损伤。我们描述了同时使用肝圆韧带和残余胆囊皮瓣成功重建胆管的方法。
    结论:肝韧带和残余胆囊皮瓣容易获得,是修复和重建胆管损伤的理想修复材料。良好的组织相容性,术后并发症发生率低。在手术中发生胆管损伤时,必须寻求经验丰富的胆道外科医生的帮助。
    结论:肝圆韧带和胆囊瓣,作为合适的自体组织,是修复胆管损伤和缺损的可行选择。
    BACKGROUND: Bile duct injuries caused by any reason are a disaster for patients and pose a significant psychological and technical challenge for surgeons. The use of Ligamentum teres hepatis and gallbladder flap as autografts is showing promising results in the repair of bile duct injury.
    METHODS: This article presents a challenging case of a patient with Mirizzi syndrome who experienced a complex bile duct defect and injury during cholecystectomy. We describe the successful reconstruction of the bile duct using ligamentum teres hepatis and remnant gallbladder flap simultaneously.
    CONCLUSIONS: Ligamentum teres hepatis and remnant gallbladder flap are ideal repair materials for repairing and reconstructing bile duct injuries due to their easy availability, good tissue compatibility, and low incidence of postoperative complications. It is essential to seek the assistance of an experienced biliary surgeon when bile duct injury occurs during operation.
    CONCLUSIONS: Ligamentum teres hepatis and gallbladder flap, as suitable autologous tissues, are viable options for repairing bile duct injuries and defects.
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  • 文章类型: Journal Article
    使用液氮冷冻灭活自体肿瘤骨骼是肉瘤患者保肢的重要手术方法。目前,关于冷冻灭活自体移植再植的研究报道很少。
    在这项研究中,回顾性收集骨及软组织肉瘤患者应用液氮冷冻灭活肿瘤骨再植的临床资料,并分析了该手术方法的安全性和有效性。使用国际保肢协会(ISOLS)评分系统评估冷冻的灭活自体移植物的愈合状态。使用肌肉骨骼肿瘤协会(MSTS)量表评估患者的功能状态。
    这项研究包括43名患者。肿瘤切除后骨缺损的平均长度为16.9cm(范围6.3-35.3cm)。不包括膝关节表面的自体移植患者的愈合结果(ISOLS评分)明显更好(80.6%±15%vs28.2%±4.9%,P<0.001)和肢体功能(MSTS评分)(87%±11.6%vs27.2%±4.4%,P<0.001)比包括膝关节表面在内的自体移植物患者。灭活自体移植物末端靠近干phy端的愈合时间明显短于远离干meta端的愈合时间(9.8±6.3个月vs14.9±6.3个月,P=0.0149)。一名患者局部复发,一个人感染了自体移植物,5人(均为自体移植,包括膝关节表面)有关节畸形,七个人骨不愈合。
    冷冻灭活自体肿瘤骨再植是安全的,骨愈合良好。但是这种方法不适用于涉及膝关节表面的自体移植患者。
    UNASSIGNED: The frozen inactivation of autologous tumor bones using liquid nitrogen is an important surgical method for limb salvage in patients with sarcoma. At present, there are few research reports related to frozen inactivated autograft replantation.
    UNASSIGNED: In this study, we retrospectively collected the clinical data of patients with bone and soft tissue sarcoma treated with liquid nitrogen-frozen inactivated tumor bone replantation, and analyzed the safety and efficacy of this surgical method. The healing status of the frozen inactivated autografts was evaluated using the International Society of Limb Salvage (ISOLS) scoring system. Functional status of patients was assessed using the Musculoskeletal Tumor Society (MSTS) scale.
    UNASSIGNED: This study included 43 patients. The average length of the bone defect after tumor resection is 16.9 cm (range 6.3-35.3 cm). Patients with autograft not including the knee joint surface had significantly better healing outcomes (ISOLS scores) (80.6% ± 15% vs 28.2% ± 4.9%, P<0.001) and limb function (MSTS score) (87% ± 11.6% vs 27.2% ± 4.4%, P<0.001) than patients with autografts including the knee joint surface. The healing time of the end of inactivated autografts near the metaphyseal was significantly shorter than that of the end far away from the metaphyseal (9.8 ± 6.3 months vs 14.9 ± 6.3 months, P=0.0149). One patient had local recurrence, one had an autograft infection, five (all of whom had an autograft including the knee joint surface) had joint deformities, and seven had bone non-union.
    UNASSIGNED: Frozen inactivated autologous tumor bone replantation is safe and results in good bone healing. But this method is not suitable for patients with autograft involving the knee joint surface.
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  • 文章类型: Journal Article
    方法:指南。
    目的:制定一项关于在颈椎前路椎间盘切除和融合术(ACDF)中使用骨生物制剂治疗退行性脊柱疾病的国际指南(AOGO)。
    方法:指南开发过程由AO脊柱知识论坛退化(KFDegen)指导,并遵循指南国际网络McMaster指南开发清单。该过程涉及来自22个国家的73名具有退行性脊柱疾病和手术专业知识的参与者。针对各自的关键主题进行了15次系统审查,并收集了证据。方法学家将证据汇编成GRADE证据到决策框架。准则小组成员对结果和其他标准进行了判断,并通过协商一致提出了最终建议。
    结果:创建了五个有条件的建议。有条件的建议是关于同种异体移植的使用,原发性ACDF手术中的自体移植物或具有骨生物学的笼子。其他有条件的建议是关于使用骨生物学治疗单级或多级ACDF,和混合构造手术。建议外科医生在常见的临床情况下使用其他骨生物制剂而不是人骨形态发生蛋白2(BMP-2)。建议外科医生主要根据临床情况选择1个移植物而不是另一个移植物或1个骨生物学移植物而不是另一个移植物。以及材料的成本和可用性。
    结论:本AOGO指南首次为ACDF中使用骨生物制剂提供了建议。尽管进行了全面的证据搜索,很少有小样本量完成的研究,主要是作为具有固有偏倚风险的病例系列.因此,需要高质量的临床证据来改进指南。
    METHODS: Guideline.
    OBJECTIVE: To develop an international guideline (AOGO) about the use of osteobiologics in anterior cervical discectomy and fusion (ACDF) for treating degenerative spine conditions.
    METHODS: The guideline development process was guided by AO Spine Knowledge Forum Degenerative (KF Degen) and followed the Guideline International Network McMaster Guideline Development Checklist. The process involved 73 participants with expertise in degenerative spine diseases and surgery from 22 countries. Fifteen systematic reviews were conducted addressing respective key topics and evidence was collected. The methodologist compiled the evidence into GRADE Evidence-to-Decision frameworks. Guideline panel members judged the outcomes and other criteria and made the final recommendations through consensus.
    RESULTS: Five conditional recommendations were created. A conditional recommendation is about the use of allograft, autograft or a cage with an osteobiologic in primary ACDF surgery. Other conditional recommendations are about the use of osteobiologic for single- or multi-level ACDF, and for hybrid construct surgery. It is suggested that surgeons use other osteobiologics rather than human bone morphogenetic protein-2 (BMP-2) in common clinical situations. Surgeons are recommended to choose 1 graft over another or 1 osteobiologic over another primarily based on clinical situation, and the costs and availability of the materials.
    CONCLUSIONS: This AOGO guideline is the first to provide recommendations for the use of osteobiologics in ACDF. Despite the comprehensive searches for evidence, there were few studies completed with small sample sizes and primarily as case series with inherent risks of bias. Therefore, high-quality clinical evidence is demanded to improve the guideline.
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  • 文章类型: Journal Article
    自1990年代以来,前交叉韧带(ACL)重建一直是主要ACL破裂的金标准。在过去的十年里,ACL修复受到了新的关注和更多的研究。
    比较现代增强ACL修复与自体移植重建治疗ACL破裂的临床结果。
    系统评价;证据水平,3.
    搜索PubMed,EMBASE,Scopus,WebofScience,2010年1月1日至2023年1月3日,对CochraneLibrary数据库进行前瞻性或回顾性比较研究,至少随访2年.两名独立的审查员进行了数据提取和方法学质量评估。进行灵敏度分析以保持结果的稳定性。
    纳入了9项研究(最短随访期,24-60个月)。总样本量为833例患者(增强修复组:358例患者;自体移植ACL重建组:475例患者)。有4项随机对照试验(1级),1项前瞻性比较研究(2级),2个回顾性比较研究(3级),和2个病例对照研究(3级)。增强ACL修复组获得了更高的Lysholm评分(加权平均差[WMD]=1.57;95%置信区间[CI],0.14-3.01;P=.03)和腿筋强度(WMD=36.69;95%CI,29.07-44.31;P<.01),但硬件去除率较高(比值比[OR]=6.30;95%CI,2.44-16.23;P=.0001),再次手术(OR=1.87;95%CI,1.33-2.62;P=.0003),与自体移植ACL重建组相比,失败(OR=1.58;95%CI,1.03-2.43;P=.0003)。修复组和重建组术后国际膝关节文献委员会评分无显著差异,Tegner得分,膝盖松弛,满意,ACL修订,并发症,重新操作而不是修改。
    增强ACL修复与更高的再手术率相关,硬件拆卸,在至少2年随访数据的研究中,与自体移植ACL重建相比失败。然而,与自体移植ACL重建相比,增强ACL修复的Lysholm评分和腿筋强度更高。
    UNASSIGNED: Anterior cruciate ligament (ACL) reconstruction has been the gold standard for primary ACL rupture since the 1990s. In the past decade, ACL repair has received renewed attention and increased research.
    UNASSIGNED: To compare the clinical outcomes of modern augmented ACL repair versus autograft reconstruction for ACL ruptures.
    UNASSIGNED: Systematic review; Level of evidence, 3.
    UNASSIGNED: A search of the PubMed, EMBASE, Scopus, Web of Science, and the Cochrane Library databases was conducted for prospective or retrospective comparative studies published between January 1, 2010, and January 3, 2023, with a minimum 2-year follow-up. Two independent reviewers performed data extraction and methodological quality assessment. Sensitivity analysis was performed to maintain the stability of results.
    UNASSIGNED: Nine studies were included (minimum follow-up period, 24-60 months). The total sample size was 833 patients (augmented repair group: 358 patients; autograft ACL reconstruction group: 475 patients). There were 4 randomized controlled trials (level 1), 1 prospective comparative study (level 2), 2 retrospective comparative studies (level 3), and 2 case-control studies (level 3). The augmented ACL repair group attained significantly higher Lysholm score (weighted mean difference [WMD] = 1.57; 95% confidence interval [CI], 0.14-3.01; P = .03) and hamstring strength (WMD = 36.69; 95% CI, 29.07-44.31; P < .01) but had higher rates of hardware removal (odds ratio [OR] = 6.30; 95% CI, 2.44-16.23; P = .0001), reoperation (OR = 1.87; 95% CI, 1.33-2.62; P = .0003), and failure (OR = 1.58; 95% CI, 1.03-2.43; P = .0003) compared with the autograft ACL reconstruction group. No significant differences were observed between the repair and reconstruction groups regarding postoperative International Knee Documentation Committee scores, Tegner scores, knee laxity, satisfaction, ACL revisions, complications, and reoperation rather than revision.
    UNASSIGNED: Augmented ACL repair was associated with higher rates of reoperation, hardware removal, and failure compared with autograft ACL reconstruction in studies with minimum 2-year follow-up data. However, augmented ACL repair had higher Lysholm scores and hamstring strength versus autograft ACL reconstruction.
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  • 文章类型: Journal Article
    背景:自体肿瘤骨的灭活和再植是恶性肿瘤患者保肢的重要手术方法。目前,关于膝关节失活和再植的报道很少。在这项研究中,我们的目的是评估我们的手术方法的可行性。
    方法:这是一项回顾性病例系列研究。我们回顾性收集应用膝关节失活再植治疗的肉瘤患者的临床资料,并分析该手术方法的疗效。评估了这些患者在灭活自体移植后的骨愈合和并发症。
    结果:本研究包括16例患者。15例患者有骨肉瘤,还有一个得了尤因肉瘤.失活骨的平均长度为20.2cm(范围13.5-25.3cm)。所有患者均行钢板内固定。随访时间8~60个月,平均30个月。在本研究的数据截止日期之前,八位(50%)患者仍然活着,8人(50%)死于肉瘤转移。八名(50%)患者在灭活的肿瘤骨的骨干部位实现了骨愈合,平均骨愈合时间为21.9个月(范围,12-36个月)。五名(31%)患者因转移而死亡,未实现骨愈合。两名(12.5%)患者由于感染而未实现骨愈合,1例(6.3%)患者因肿瘤复发而截肢。10例(62.5%)患者在未激活的再植骨的关节端周围发生骨折,这10例患者中有8例合并关节脱位。
    结论:膝关节失活和再植后关节畸形的发生率极高,不推荐使用。
    BACKGROUND: The inactivation and replantation of autologous tumor bones are important surgical methods for limb salvage in patients with malignancies. Currently, there are few reports on the inactivation and replantation of the knee joint. In this study, we aimed to evaluate the feasibility of our surgical approach.
    METHODS: This is a retrospective case series study. We retrospectively collected the clinical data of patients with sarcoma treated with knee joint inactivation and replantation and analyzed the efficacy of this surgical method. The bone healing and complications in these patients after inactivated autograft replantation were assessed.
    RESULTS: This study included 16 patients. Fifteen patients had osteosarcoma, and one had Ewing\'s sarcoma. The average length of the inactivated bone is 20.2 cm (range 13.5-25.3 cm). All the patients underwent internal plate fixation. The average follow-up duration was 30 months (range 8-60 months). Before the data deadline of this study, eight (50%) patients were still alive, and eight (50%) died of sarcoma metastasis. Eight (50%) patients achieved bone healing at the diaphysis site of the inactivated tumor bone, with an average bone healing time of 21.9 months (range, 12-36 months). Five (31%) patients died due to metastases and did not achieve bone healing. Two (12.5%) patients did not achieve bone healing because of infection, and one (6.3%) patient underwent amputation due to tumor recurrence. Ten (62.5%) patients experienced fractures around the joint ends of the inactivated replanted bone, and eight of these ten patients were combined with joint dislocation.
    CONCLUSIONS: The incidence of joint deformities after the knee-joint inactivation and replantation is extremely high and is not recommended for use.
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  • 文章类型: Meta-Analysis
    目的:本研究旨在确定使用自体移植结合或不结合韧带增强的前交叉韧带重建(ACLR)的功效。
    方法:对数据库进行了计算机搜索,包括PubMed,WebofScience,Embase,Scopus和Cochrane图书馆。仅考虑纳入至少2年随访的前瞻性或回顾性比较研究。两名独立的审查员进行了数据提取和方法学质量评估。Mantel-Haenszel分析用于汇集结果。进行灵敏度分析以保持结果的稳定性。采用egger检验评估发表偏倚。
    结果:纳入14项研究。总队列为1353名患者(非增强组:763名患者;增强组:590名患者)。有三项随机对照试验(随机对照试验,一级),6项回顾性比较研究(III级)和5项病例对照研究(III级).所有纳入研究的随访率≥88%,随访时间≥24个月。用于与自体移植物比较的增强移植物包括韧带增强装置(LAD),韧带高级加固系统(LARS)人工韧带,FiberTape,绳肌腱同种异体移植,可降解聚氨酯脲。在术后患者报告结果(PRO)方面,增强组和非增强组之间没有观察到显着差异。包括国际膝盖文献委员会的分数,Lysholm得分和Tegner得分,膝盖松弛,包括KT-1000,侧面差异,Lachman试验和枢轴移位和移植物失败率。
    结论:使用自体移植物联合韧带增强的ACLR在PRO中没有优势,与仅使用自体移植物相比,膝关节松弛和移植物失败率。
    方法:三级。
    背景:研究方案已在PROSPERO数据库(CRD42022324784)中注册。
    OBJECTIVE: This study aims to determine the efficacy of anterior cruciate ligament reconstruction (ACLR) using autograft combined with or without ligament augmentation.
    METHODS: A computerized search of the databases was conducted, including PubMed, Web of Science, Embase, Scopus and the Cochrane Library. Only prospective or retrospective comparative studies with a minimum 2-year follow-up were considered for inclusion. Two independent reviewers performed data extraction and methodological quality assessment. A Mantel-Haenszel analysis was used for the pooling of results. Sensitivity analysis was performed to maintain the stability of results. The egger test was applied to assess the publication bias.
    RESULTS: Fourteen studies were included. The total cohort was 1353 patients (non-augmented group: 763 patients; augmented group: 590 patients). There were three Randomized Controlled Trials (RCTs, Level I), six retrospective comparative studies (Level III) and five case-control studies (Level III). The follow-up rate was ≥ 88% and the follow-up periods were ≥ 24 months in all included studies. The augmented graft used to compare with autograft included the Ligament Augmentation Device (LAD), the Ligament Advanced Reinforcement System (LARS) artificial ligament, FiberTape, hamstring tendon allograft, degradable poly (urethane urea). No significant differences were observed between the augmented and non-augmented groups regarding postoperative patient-reported outcomes (PROs), including the International Knee Documentation Committee score, Lysholm score and Tegner score, knee laxity, including KT-1000, side-to-side difference, Lachman test and pivot shift and rate of graft failure.
    CONCLUSIONS: ACLR using autografts combined with ligament augmentation shows no advantages in PROs, knee laxity and graft failure rate compared with using autografts only.
    METHODS: Level III.
    BACKGROUND: The research protocol was registered at the PROSPERO database (CRD42022324784).
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  • 文章类型: Journal Article
    /purpose:骨环技术(BRT)是一种通过同时放置植入物来重建牙槽骨缺损的有效方法。本研究旨在评估BRT在单颗上颌前牙种植中的疗效及其在2-3年随访期间的美学效果。
    15例单上颌切牙缺失患者接受了自体BRT并同时植入。垂直/水平骨骼增益,剩余垂直骨高度(RVBH),剩余颊骨宽度(RBBW),在2-3年的随访中,通过使用锥形束计算机断层扫描测量植入物周围的垂直/水平骨吸收。美学结果包括白色美学评分(WES),粉红色的审美得分(PES),通过临床记录照片评估乳头指数(PI)。
    所有植入物都显示了骨整合的证据,14个部位的平均垂直和水平骨增益分别为5.55±0.87mm和4.73±0.70mm,分别。在2-3年的随访中,所有RBBW的平均值均大于2mm。术后4个月内出现主要垂直骨丢失,随着随访时间的持续,RVBH值降低。在最初的两个随访期间,最大颊骨厚度吸收主要出现在植入物的中层(P<0.05)。美学结果表明,平均WES/PES高于17,超过一半的病例在整个随访期间表现出相对较高的PI(3分)。
    BRT可以实现出色的骨增强效果,并且可以为美学区域的单牙种植修复提供可预测的美学效果。
    UNASSIGNED: /purpose: Bone ring technique (BRT) is an effective method to reconstruct alveolar bone defects with simultaneous implant placement. This study aimed to evaluate the efficacy of the BRT in single maxillary anterior tooth implantation and its esthetic outcomes over 2-3 years of follow-up.
    UNASSIGNED: Fifteen patients with single maxillary incisor loss received autogenous BRT with simultaneous implant placement. The vertical/horizontal bone gain, remaining vertical bone height (RVBH), remaining buccal bone width (RBBW), and vertical/horizontal bone resorption around implant over 2-3 years of follow-up were measured by using cone-beam computed tomography. Esthetic results including white esthetic score (WES), pink esthetic score (PES), and papilla index (PI) were evaluated by clinical recorded photographs.
    UNASSIGNED: All implants showed evidence of osseointegration, and the mean vertical and horizontal bone gain of 14 sites was 5.55 ± 0.87 mm and 4.73 ± 0.70 mm, respectively. During 2-3 years of follow-up, all mean values of RBBW were more than 2 mm. Main vertical bone loss appeared within 4 months after surgery and the RVBH value decreased as the follow-up duration continued. Maximum buccal bone thickness resorption mostly appeared in the middle level of the implant during the primary two follow-up periods (P < 0.05). Esthetic results showed that the mean WES/PES was higher than 17, and more than half cases demonstrated relatively high PI (3 points) throughout the follow-up.
    UNASSIGNED: BRT could achieve excellent bone augmentation effect and can offer predictable esthetic outcomes for single tooth implant restoration in the esthetic zone.
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  • 文章类型: Case Reports
    背景:蝶眶脑膜瘤(SOM)是一种罕见的颅内病变,伴有骨内肥大和眶内扩张。
    方法:我们描述了一名患有SOM的中年女性,她接受了显微神经外科手术治疗。定制钛植入物并应用于重建眶壁以防止术后眼球内陷。
    结论:尽管有技术要求,有利的化妆品,根治性切除术后,通过细致的手术技术可以实现无并发症的临床结局。
    背景:NA。
    Spheno-orbital meningioma (SOM) is a rare intracranial pathology with intraosseous hypertrophy and intraorbital extension.
    We described a middle-aged female with SOM who was managed in a micro-neurosurgical manner. The titanium implant was customized and applied to rebuild the orbital wall to prevent postoperative enophthalmus.
    Despite technical demands, favorable cosmetic, and clinical outcomes without complications can be achieved by meticulous surgical technique following radical resection.
    NA.
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  • 文章类型: Journal Article
    目的:修补技术已成为治疗肩袖部分厚度撕裂(PTRCT)的新技术,以解决传统技术的局限性。与同种异体斑块和人工材料相比,喙肩峰韧带明显更接近自身生物学。该研究的目的是评估关节镜下自体喙肩峰韧带增强技术治疗PTRCT后的功能和影像学结果。
    方法:本研究包括3名女性PTRCT患者,他们在2017年接受了关节镜手术,平均年龄为51岁(50至52岁)。将喙肩峰韧带植入物附着在肌腱的囊侧表面。通过美国肩肘外科医师(ASES)评分评估临床结果,简单肩部测试(SST),术前和术后12个月肩关节距离(AHD)和肌力。术后24个月进行磁共振成像(MRI),以评估原始撕裂部位解剖结构的完整性。
    结果:平均ASES评分从术前的57.3显著提高到1年随访时的95.0。从术前的3级到1年的5级,强度显着提高。在2年的随访中,三名患者中有两名接受了MRI检查。射线照相释放了肩袖撕裂的完全愈合。未报告植入物相关严重不良事件。
    结论:使用自体喙肩峰韧带补片的新技术对PTRCT患者具有良好的临床效果。
    OBJECTIVE: Patch technology has been the new technique in the treatment of partial thickness of the rotator cuff tear (PTRCTs) to address the limitation of traditional techniques. Compared with allogeneic patches and artificial materials, coracoacromial ligament is obviously closer to their own biology. The purpose of the study was to evaluate the functional and radiographic outcomes following arthroscopic autologous coracoacromial ligament augment technique for treatment of PTRCTs.
    METHODS: This study included three female patients with PTRCTs who underwent arthroscopy operation in 2017 with an average age of 51 years (range from 50 to 52 years). The coracoacromial ligament implant was attached to the bursal side surface of the tendon. The clinical results were evaluated by American Shoulder and Elbow Surgeons (ASES) score, Simple Shoulder Test (SST), acromiohumeral distance (AHD) and muscle strength before and 12 months after operation. Magnetic resonance imaging (MRI) was performed 24 months after operation to assess the integrity of the anatomical structure of the original tear site.
    RESULTS: The average ASES score improved significantly from 57.3 preoperatively to 95.0 at 1-year follow-up. The strength improved significantly from grade 3 preoperatively to grade 5 at 1 year. Two of three patients underwent the MRI at 2-year follow-up. Radiographic released the complete healing of rotator cuff tear. No implant-related serious adverse events were reported.
    CONCLUSIONS: The new technique of using autogenous coracoacromial ligament patch augment provides good clinical results on patients with PTRCTs.
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  • 文章类型: Journal Article
    UASSIGNED:移植物成熟是自体绳肌腱移植前交叉韧带重建(ACLR)的重要预后因素。目前尚不清楚体外冲击波疗法(ESWT)是否可以促进ACLR后的移植物愈合。
    UNASSIGNED:评估ESWT在自体肌腱移植ACLR中的治疗和移植物成熟效果。
    未经批准:随机对照试验;证据水平,1.
    UNASSIGNED:在2019年5月18日至2019年9月20日之间,我们将30名符合研究纳入标准的患者随机分为两组。对照组患者遵循为期5周的高级康复训练计划(30分钟/次,5次/周)从术后3个月开始。在ESWT组中,加上为期5周的高级康复训练,放射状ESWT每周应用一次,共5周。功能评分(Lysholm,国际膝关节文献委员会,和Tegner得分),KT-1000关节仪膝关节松弛度测量,和磁共振成像扫描在3个月(基线)进行评估,6个月,术后24个月。为了评估移植物成熟,我们评估了胫骨的移植物信噪比(SNQs),关节内,和磁共振成像扫描的股骨侧。比较ESWT组和对照组的数据。
    未经批准:总共,26例患者(13例ESWT,13个对照)进行了评估。基线时的任何评估均无显着组间差异,在任何时间点,膝关节松弛均未发现明显的组内或组间差异。在24个月的随访中,与对照组相比,ESWT组的Lysholm和Tegner评分显著较高(分别为P=.012和.017).关于移植物成熟,在6个月的随访中,与对照组相比,ESWT组的胫骨骨内移植物的SNQ明显降低(P=.006),但是在股骨骨内移植物(P=.321)或关节内移植物(P=.314)中未检测到差异。在24个月的随访中,ESWT组的股骨骨内移植物和关节内移植物的SNQs显著低于对照组(分别为P=.020和.044),但胫骨骨内移植物的SNQs无差异(P=.579).
    UNASSIGNED:在24个月的随访中,在自体肌腱移植ACLR后的康复期间接受放射状ESWT的患者中观察到了增强的移植物成熟和改善的功能评分。
    未经批准:ChiCTR1900022853(中国临床试验注册中心)。
    UNASSIGNED: Graft maturation is an important prognostic factor for hamstring autograft anterior cruciate ligament reconstruction (ACLR). It remains unclear whether extracorporeal shock wave therapy (ESWT) can promote graft healing after ACLR.
    UNASSIGNED: To evaluate the therapeutic and graft maturation effects of ESWT in hamstring autograft ACLR.
    UNASSIGNED: Randomized controlled trial; Level of evidence, 1.
    UNASSIGNED: Between May 18, 2019, and September 20, 2019, we randomly assigned 30 patients who met study inclusion criteria to 2 groups. Patients in the control group followed a 5-week advanced rehabilitation training program (30 minutes/session, 5 times/week) starting at 3 months postoperatively. In the ESWT group, together with the 5-week advanced rehabilitation training, radial ESWT was applied once a week for 5 weeks. Functional scores (Lysholm, International Knee Documentation Committee, and Tegner scores), KT-1000 arthrometer knee laxity measurement, and magnetic resonance imaging scans were assessed at 3 months (baseline), 6 months, and 24 months postoperatively. To evaluate graft maturation, we assessed the graft signal-to-noise quotients (SNQs) of the tibial, intra-articular, and femoral sides on magnetic resonance imaging scans. Data were compared between the ESWT and control groups.
    UNASSIGNED: In total, 26 patients (13 with ESWT, 13 controls) were assessed. There were no significant between-group differences on any assessment at baseline, and no significant within-group or between-group differences were found in knee laxity at any point. At 24-month follow-up, the ESWT group had significantly higher Lysholm and Tegner scores compared with the controls (P = .012 and .017, respectively). Regarding graft maturation, at 6-month follow-up, the SNQ of the tibial intraosseous graft was significantly lower in the ESWT group versus controls (P = .006), but no differences were detected at the femoral intraosseous graft (P = .321) or the intra-articular graft (P = .314). At 24-month follow-up, the SNQs of the femoral intraosseous graft and intra-articular graft were significantly lower in the ESWT group versus controls (P = .020 and .044, respectively) but no difference was found at the tibial intraosseous graft (P = .579).
    UNASSIGNED: Both enhanced graft maturation and improved functional scores at 24-month follow-up were seen in patients who received radial ESWT during rehabilitation after hamstring autograft ACLR.
    UNASSIGNED: ChiCTR1900022853 (Chinese Clinical Trial Registry).
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