UNASSIGNED:木村病(Kimura'sdisease,KD)是一种罕见的嗜酸性细胞增生性淋巴疾病,临床症状无特异性。
未经批准:为了研究临床特征,诊断,治疗,和KD的预后。
未经证实:临床表现,实验室检查,影像学检查,建议的治疗,对我院收治的20例KD患者的预后进行回顾性分析。
未经证实:所有病例均表现为无痛肿块。18例(90%)外周血嗜酸性粒细胞比例上升,14例(70%)患者的嗜酸性粒细胞计数增加,5例(100%)患者的血清免疫球蛋白E(IgE)水平显着增加。病理检查提示滤泡增生,嗜酸性粒细胞浸润,KD样本中的微小血管增殖。
UASSIGNED:当患者遭受头颈部皮下无痛性肿块时,应考虑KD,外周血嗜酸性粒细胞增加,血清IgE水平升高。病理检查是诊断KD的金标准。手术干预,医疗,放疗可能对KD治疗有效。
未经评估:这项研究可能有助于改善KD的诊断和治疗。
UNASSIGNED: Kimura\'s disease (KD) is an eosinophilic proliferative lymphoid disease with rare incidence rate and nonspecific clinical symptoms.
UNASSIGNED: To investigate the clinical characteristics, diagnosis, treatment, and prognosis of KD.
UNASSIGNED: The clinical manifestations, laboratory examination, imaging examination, proposed treatment, and prognosis of 20 patients with KD treated in our hospital were retrospectively analyzed.
UNASSIGNED: All cases showed painless masses. The proportion of peripheral blood eosinophils rose in 18 cases (90%), the eosinophil count increased in 14 cases (70%) and the serum immunoglobulin E (IgE) levels were significantly increased in 5 patients (100%). Pathological examination revealed follicular hyperplasia, eosinophils infiltration, and tiny vessels proliferation in KD samples.
UNASSIGNED: KD should be considered when the patients suffered head and neck subcutaneous painless mass, increased peripheral blood eosinophils and raised serum IgE level. Pathological examination is the golden standard for diagnosing KD. Surgical intervention, medical treatments, and radiotherapy may be effective for KD treatment.
UNASSIGNED: This study might shed a light on improving the diagnosis and treatment for KD.