ureter

输尿管
  • 文章类型: Case Reports
    腹股沟疝是常见的,主要由外科医生管理;然而,对于腹膜后结构来说是不寻常的,比如输尿管,突出它。更重要的是,包含输尿管的疝通常不会在术前发现,除非事先订购了特定的影像学检查,因为它们通常是无症状的。这对患者造成风险,因为未识别的结构可能在手术期间被错误地损伤。我们描述了一个60多岁的男人的案例,他出现了一个巨大的左侧间接腹股沟腹疝。术中,除了绳状结构外,还遇到了大量不可还原的腹膜后脂肪,术中复查影像学后发现是左输尿管。最初,疝气修复是用机器人完成的,但由于其不可还原性和对输尿管的潜在风险,它被转换为开放式修复。此外,我们讨论了这种疝气的病因和常见表现。
    Inguinal hernias are commonly encountered and are primarily managed by surgeons; however, it is unusual for retroperitoneal structures, such as the ureter, to herniate into it. More importantly, hernias containing ureters are not usually identified preoperatively unless specific imaging was ordered prior, as they are generally asymptomatic. This poses a risk to the patient as unidentified structures can be mistakenly injured during the surgery. We describe a case of a man in his 60s, who presented with a large left-sided indirect inguinoscrotal hernia. Intraoperatively, a large amount of irreducible retroperitoneal fat was encountered in addition to a cord-like structure, which was discovered to be the left ureter after reviewing imaging intraoperatively. Initially, the hernia repair was done robotically, but it was converted to open repair due to its irreducibility and the potential risk imposed on the ureter. Additionally, we discuss the aetiology and common presentations of this kind of hernia.
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  • 文章类型: Case Reports
    我们经历了一个罕见的病例,其中髂腰肌脓肿(IPA),由产超广谱β-内酰胺酶(ESBL)的奇异变形杆菌引起,穿孔并与输尿管连通,导致败血症。一个84岁的女人,因脑出血后遗症卧床不起,被带到我们医院,主要投诉发烧持续3周。计算机断层扫描(CT)显示右髂腰肌巨大的180×110×100mmIPA。还发现输尿管与髂腰肌脓肿有交流,在同一部位检测到输尿管狭窄,肾盂扩张发生在输尿管狭窄区域上方,提示肾积水.考虑到这种情况的机制,如果输尿管首先破裂并且尿液泄漏,随后形成了IPA,尿液会沿着周围的脂肪组织流动,并在输尿管和肾脏周围引起脓肿。然而,因为输尿管周围几乎没有发现脓肿,脓肿被认为起源于输尿管中心附近的髂腰肌。总之,在这种情况下,脓肿首先在髂腰肌形成,逐渐扩张并压缩右输尿管,导致肾积水.输尿管上段,由于输尿管阻塞而变得扩张和变薄,由于IPA的炎症扩散,变得更加脆弱,IPA穿孔并与输尿管连通。在沟通困难的患者中,IPA的诊断可能会延迟,因为唯一的症状是发烧。在这种情况下,如果诊断延迟,脓肿可能会变大并穿孔输尿管;因此,IPA应始终被视为不明原因的发烧的原因。
    We experienced a rare case in which iliopsoas abscess (IPA), caused by an Extended Spectrum β-Lactamase (ESBL)-producing Proteus mirabilis, perforated and communicated with the ureter and caused sepsis. An 84-year-old woman, bedridden due to sequelae of a cerebral hemorrhage, was brought to our hospital with a chief complaint of fever lasting for 3 weeks. Computed tomography (CT) revealed a huge 180 × 110 × 100 mm IPA in the right iliopsoas muscle. The ureter was also found to communicate with the iliopsoas muscle abscess, ureteral stenosis was detected at the same site, and dilatation of the renal pelvis occurred above the area of the ureteral stenosis, indicating hydronephrosis. Considering the mechanism of this case, if the ureter first ruptures and urine leaks, followed by the formation of an IPA, urine will flow along the surrounding fatty tissue and cause an abscess around the ureter and kidney. However, because almost no abscess was detected around the ureter, the abscess was thought to have originated from the iliopsoas muscle located near the center of the ureter. In summary, in this case, an abscess first formed within the iliopsoas muscle, which gradually expanded and compressed the right ureter, resulting in hydronephrosis. The upper ureter, which had become dilated and thinned due to ureteral obstruction, became even more fragile because of the spread of inflammation from the IPA, and the IPA perforated and communicated with the ureter. In patients who have difficulty communicating, the diagnosis of IPA may be delayed because the only symptom is fever. As in this case, if the diagnosis is delayed, the abscess may become large and perforate the ureter; thus, IPA should always be considered as a cause of fever of unknown origin.
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  • 文章类型: Journal Article
    目的:为了评估基于CT扫描的参数,特别是输尿管壁厚度(UWT),预测自发性输尿管结石通道。
    方法:横截面,分析研究。研究的地点和持续时间:泌尿外科部分,外科,阿加汗大学医院,卡拉奇,巴基斯坦,2023年6月至11月。
    方法:有症状的患者,单身,不透射线,单侧输尿管结石,大小≤10mm,肾功能正常,通过非造影CT扫描KUB诊断,并接受保守治疗4周。结石通道(SP)的临床和放射学预测因子,包括石头尺寸,area,偏侧性,location,密度,肾积水程度,结石部位的最大UWT,以及结石上方和下方的输尿管直径和密度,进行了评估。采用二元逻辑回归分析确定结石通过的预测因子。接收器工作特性(ROC)曲线用于找到UWT的最佳截止值。
    结果:在34名符合条件的患者中,22(64.7%)自发通过结石。通过的患者结石大小和面积较小,UWT较小。石头位置,偏侧性,肾积水程度,石材密度,输尿管壁直径,结石上方和下方的密度与SP无关。多变量分析显示最大UWT是SP的独立预测因子,具有1.95毫米的截止和0.94的精度。
    结论:UWT是本研究中输尿管结石自发通过的唯一最有说服力的因素。通过应用UWT的最佳截止值,在日常实践中做出决定时,它可能是一个非常重要的工具。
    背景:输尿管壁厚,医疗驱逐疗法,非对比计算机断层扫描。
    OBJECTIVE: To assess CT-scan based parameters, particularly ureteral wall thickness (UWT), in predicting spontaneous ureteral stone passage.
    METHODS: Cross-sectional, analytical study. Place and Duration of the Study: Section of Urology, Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan, from June to November 2023.
    METHODS: Patients with symptomatic, single, radio-opaque, unilateral ureteral stones having size ≤10 mm with normal kidney functions, diagnosed by non-contrast CT-scan KUB, and treated by conservative option for four weeks were enrolled. Clinical and radiological predictors for stone passage (SP), including stone size, area, laterality, location, density, degree of hydronephrosis, maximal UWT at the stone site, and ureteral diameter and density above and below the stone, were evaluated. Binary logistic regression analysis was employed to identify predictors of stone passage. Receiver operating characteristic (ROC) curve was used to find the optimal cut-off for UWT.
    RESULTS: Among 34 eligible patients, 22 (64.7%) passed their stones spontaneously. Patients who passed had smaller stone size and area and lesser UWT. Stone location, laterality, degree of hydronephrosis, stone density, ureteral wall diameter, and density above and below stones were not associated with SP. Multivariate analysis revealed maximum UWT as the independent predictor of SP, with a cut-off of 1.95 mm and an accuracy of 0.94.
    CONCLUSIONS: UWT was the single most convincing factor for the spontaneous passage of ureteral stone in this study. By applying UWT\'s optimal cut-off value, it might be an extremely significant tool when taking decisions in daily practice.
    BACKGROUND: Ureteral wall thickness, Medical expulsive therapy, Non-contrast computed tomography.
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  • 文章类型: Journal Article
    目的:报告我们在输尿管上段或肾结石中使用11/13Fr吸引输尿管入路鞘(UAS)和8.55Fr一次性数字输尿管软镜(SDFU)进行一期输尿管软镜碎石(FURL)的初步经验。
    方法:我们回顾性收集了2022年1月至2024年4月的900例成人输尿管上段或肾结石患者的临床资料。人口统计,评估围手术期和术后结局.
    结果:总而言之,940例中的40例(4.26%)由于输尿管狭窄而未能引入UAS并需要第二阶段FURL,因此被排除在外。其余900例合格病例的平均结石最大直径为1.68±0.58cm。输尿管上段结石228例,肾结石456例,合并输尿管和肾结石216例。平均手术时间为52.20±20.21min,术后住院时间为2.87±1.37d。术后1个月的结石清除率为89.56%,只有2.44%的残留物患者进行了再次手术。术后发热率,术后需要镇痛的疼痛和轻微的输尿管粘膜损伤占5.11%,8.22%和7.78%,分别。没有患者出现严重的并发症,如败血症或输尿管穿孔。
    结论:对于绝大多数成年患者来说,在没有术前支架的情况下,以11/13Fr吸引UAS的单次治疗中接受FURL是实用且适用的。FURL与11/13Fr抽吸UAS和8.55FrSDFU是可行的,可靠,安全,有效治疗肾结石和输尿管上段结石。
    OBJECTIVE: To report our initial experience of one-stage flexible ureteroscopic lithotripsy(FURL) with 11/13Fr suctioning ureteral access sheath(UAS) and 8.55Fr single-use digital flexible ureteroscope(SDFU) in upper ureteral or renal calculi.
    METHODS: We retrospectively collected the clinical data of 900 adult patients with upper ureteral or renal calculi treated by FURL with 11/13Fr suctioning UAS and 8.55Fr SDFU from January 2022 to April 2024. Demographics, peri- and postoperative outcomes were assessed.
    RESULTS: In all, 40 of 940 cases(4.26%) failed to introduce UAS and required second-stage FURL because of ureterostenosis and were excluded. Mean stones size of the remaining 900 eligible cases was 1.68 ± 0.58 cm in greatest diameter. There were 228 cases of upper ureteral stone, 456 cases of renal stone and 216 cases of concomitant ureteral and renal calculi. The mean operation time was 52.20 ± 20.21 min and the postoperative hospital stay was 2.87 ± 1.37 days. The stone-free rate of 1 month postoperatively was 89.56% and only 2.44% of patients with residue underwent additional reoperation. The rate of postoperative fever, postoperative pain needing analgesic and slight ureteral mucosal injury were 5.11%, 8.22% and 7.78%, respectively. None of patient suffered from severe complications, such as sepsis or ureteral perforation.
    CONCLUSIONS: It\'s practical and suitable for the vast majority of adult patients to undergo FURL in single session with 11/13Fr suctioning UAS without preoperative stenting. FURL with 11/13Fr suctioning UAS and 8.55Fr SDFU is feasible, reliable, safe, and efficient in the management of renal stone and upper ureteral stone.
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  • 文章类型: Journal Article
    结石大小和位置是预测自发结石通过(SSP)的关键因素,但是很少注意结石撞击(RSSI)的放射学迹象的影响。这项研究旨在确定RSSI,旁边的石头大小,可以预测SSP并评估观察者之间输尿管壁厚度(UWT)测量的一致性。在这项回顾性研究中,分析了160例急性非增强计算机断层扫描(NCCT)上输尿管上或中输尿管结石的患者。从医疗记录中收集患者数据。RSSI的测量,包括UWT,输尿管直径,和石头上方和下方的平均衰减,由四名对结果视而不见的独立读者对NCCT采取。该队列由70%的男性组成,平均年龄为51±15岁。61%的患者发生SSP超过20周。中位结石长度为5.7mm(IQR:4.5-7.3),在短结石通过的患者中明显较短(4.6vs.7.1,p<0.001)和长期(4.8与7.1,p<0.001)随访。对于石头长度,用于预测SSP的受试者工作特征曲线下面积(AUC)为0.90(CI0.84-0.96),当增加输尿管直径和UWT时,仅增加至0.91(CI0.85-0.95).输尿管衰减不能预测SSP(AUC<0.5)。UWT的观察者间变异性中等,具有±2.0mm的多阅读器协议极限(LOA)。结果表明,RSSI并不能提高结石大小对SSP的预测价值。UWT测量表现出中等的可靠性,并且观察者之间存在显着差异。
    Stone size and location are key factors in predicting spontaneous stone passage (SSP), but little attention has been paid to the influence of radiological signs of stone impaction (RSSI). This research aims to determine whether RSSI, alongside stone size, can predict SSP and to evaluate the consistency of ureteral wall thickness (UWT) measurements among observers. In this retrospective study, 160 patients with a single upper or middle ureteral stone on acute non-enhanced computed tomography (NCCT) were analysed. Patient data were collected from medical records. Measurements of RSSI, including UWT, ureteral diameters, and average attenuation above and below the stone, were taken on NCCT by four independent readers blind to the outcomes. The cohort consisted of 70% males with an average age of 51 ± 15. SSP occurred in 61% of patients over 20 weeks. The median stone length was 5.7 mm (IQR: 4.5-7.3) and was significantly shorter in patients who passed their stones at short- (4.6 vs. 7.1, p < 0.001) and long-term (4.8 vs. 7.1, p < 0.001) follow-up. For stone length, the area under the receiver operating characteristic curve (AUC) for predicting SSP was 0.90 (CI 0.84-0.96) and only increased to 0.91 (CI 0.85-0.95) when adding ureteral diameters and UWT. Ureteral attenuation did not predict SSP (AUC < 0.5). Interobserver variability for UWT was moderate, with ± 2.0 mm multi-reader limits of agreement (LOA). The results suggest that RSSI do not enhance the predictive value of stone size for SSP. UWT measurements exhibit moderate reliability with significant interobserver variability.
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  • 文章类型: Case Reports
    背景:交叉融合肾异位(CFRE)是一种常见的先天性异常,其中一个肾脏异常位于中线的另一侧,经常与另一个肾脏融合。然而,单个输尿管引流交叉融合肾异位是罕见的。
    方法:这里,我们报告了一例有结石病史的46岁尼泊尔男性患者的交叉融合性肾异位伴单个输尿管。计算机断层扫描显示左肾位于右侧并与右肾融合。两个肾脏的肾盂融合,和一个输尿管,位于右侧,将两个肾脏排入膀胱。建议患者定期随访。
    结论:单输尿管交叉融合肾异位是一种罕见的肾脏异常。无症状患者通常可以保守治疗。建议定期随访以监测肾功能,微积分形成,感染,和恶性变化。
    BACKGROUND: Crossed fused renal ectopia (CFRE) is a common congenital anomaly where one kidney is positioned abnormally on the opposite side of the midline, often fused with the other kidney. However, single ureter draining crossed fused renal ectopia is a rare occurrence.
    METHODS: Here, we report a case of crossed fused renal ectopia with a single ureter in a 46-year-old Nepali male who presented with history of lithuria. Computed tomography revealed that the left kidney was situated on the right side and fused with the right kidney. The renal pelvises of both kidneys were fused, and a single ureter, located on the right side, was draining both kidneys into the bladder. The patient was advised to have regular follow-ups.
    CONCLUSIONS: Crossed fused renal ectopia with a single ureter represents a rare renal anomaly. Asymptomatic patients can typically be managed conservatively. Regular follow-up is recommended to monitor renal function, calculus formation, infections, and malignant changes.
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  • 文章类型: Journal Article
    医源性输尿管损伤是一种严重的手术并发症,妇科手术发病率最高,为1.5%。本报告的目的是记录我们在妇科腹腔镜手术中使用亚甲蓝(MB)标记输尿管的初步经验,并探讨其有效性和安全性。这也是使用同一相机同时可视化输尿管MB荧光和前哨淋巴结(SLN)吲哚菁绿(ICG)荧光的新颖描述。
    这项研究包括接受妇科腹腔镜手术的患者,同一位外科医生进行所有病例。在每次手术的早期阶段,快速静脉输注MB.对于需要SLN成像的情况,我们还将ICG溶液注入子宫颈。在术中和术后对纳入病例进行评估。将具有MB荧光的组(组A)与不具有MB荧光的对照组(组B)进行比较。
    共有25名患者(A组)在手术过程中接受了MB,清晰地展示了45条输尿管,成像成功率达90%。在输尿管肾积水的情况下,可以实现连续且更清晰的荧光成像。在大多数患者中,静脉输注MB后15-20分钟可见输尿管荧光,64%的患者在手术结束时仍表现出荧光。在同时患有ICG和MB的患者中,清晰地实现了双荧光成像。在包括的案件中,没有医源性输尿管损伤(0%),我们观察到低于未接受MB的患者(1.3%)。两组的不良事件发生率相似。
    使用MB荧光是在妇科手术期间可视化输尿管的有效且安全的方法,并且可以减少医源性输尿管损伤,而不会增加相关的不良事件。为临床应用提供了广阔的前景。
    UNASSIGNED: Iatrogenic ureteral injury is a severe surgical complication, with a highest incidence of 1.5% in gynecological surgeries. The purpose of this report is to document our initial experience with using methylene blue (MB) to label the ureter in gynecological laparoscopic surgeries and to explore its effectiveness and safety. This is also a novel description of simultaneously visualizing ureteral MB fluorescence and sentinel lymph nodes (SLN\'s) Indocyanine Green (ICG) fluorescence using the same camera.
    UNASSIGNED: This study included patients undergoing gynecological laparoscopic surgeries, with the same surgeon performing all cases. During the early stages of each surgery, rapid intravenous infusion of MB was administered. For cases requiring SLN imaging, we also injected ICG solution into the cervix. Assessment of the included cases was conducted both intraoperatively and postoperatively. The group that had MB fluorescence (Group A) was compared to a control group that did not have it (Group B).
    UNASSIGNED: A total of 25 patients (Group A) received MB during surgery, demonstrating 45 ureters clearly, with an imaging success rate of 90%. Continuous and clearer fluorescence imaging was achieved in cases with ureteral hydronephrosis. In most patients, ureteral fluorescence was visible 15-20 min after intravenous infusion of MB, and 64% still exhibited fluorescence at the end of the surgery. In patients who had both ICG and MB, dual fluorescence imaging was achieved clearly. Among the included cases, there were no iatrogenic ureteral injuries (0%), which we observed to be lower than in patients who did not receive MB (1.3%). The rate of adverse events was similar in both groups.
    UNASSIGNED: Using MB fluorescence is an effective and safe method of visualizing the ureters during gynecological surgeries, and can diminish iatrogenic ureteral injury without increased associated adverse events. It therefore may offer promising prospects for clinical application.
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  • 文章类型: Journal Article
    目的:巨(MU)在成人中是一种罕见的疾病。目的是对当前文献进行回顾。
    方法:进行了文献检索,以探索当前文献,包括2003-2023年成人MU的病例报告。每个病例的特点是八类:性别,年龄,病因学,location,症状,使用的诊断工具,治疗类型和随访。
    结果:没有荟萃分析,只有两篇综述。总计,根据35篇文章,纳入39例病例报告。前四类最常见的观察结果是男性(性别),40岁以下(年龄),阻塞MU(病因)和左侧MU(位置)。几乎每个病人都有症状,最常见的是侧腹疼痛,腹痛和尿路感染复发。CT扫描和经腹超声检查是最常用的诊断工具。大多数病例都接受了腹腔镜或开放手术治疗,其中输尿管重植术是最有效的手术方法。大多数患者都进行了顺利的随访。
    结论:MU在成人中是一种罕见的疾病,表现为异质性症状。CT扫描和经腹超声检查应用作诊断工具。几乎所有患者都接受了手术治疗,并进行了顺利的随访。诸如结石形成和受影响的肾脏的功能改变的并发症是常见的。建议手术治疗,并根据年龄确定,症状,输尿管延伸和肾功能进行性丧失。
    OBJECTIVE: Megaureter (MU) is an uncommon condition in adults. The aim is to present a review of the current literature.
    METHODS: A literature search was conducted to explore the current literature including case reports on MU in adults in the period 2003-2023. Each case was characterised in terms of the eight categories: sex, age, etiology, location, symptoms, diagnostic tool used, type of treatment and follow-up.
    RESULTS: There was no meta-analysis but two reviews. Total, 39 case reports were included based on 35 articles. The most common observations for the first four categories were male (sex), age below 40 (age), obstructed MU (etiology) and left-sided MU (location). Almost every patient appeared with symptoms, most frequently flank pain, abdominal pain and recurrent urinary tract infections. CT scan and transabdominal ultrasonography are the most commonly used diagnostic tools. Most cases underwent either laparoscopic or open surgical treatment with ureteral reimplantation as the most performed surgical procedure. A majority of the patients had an uneventful follow-up.
    CONCLUSIONS: MU in adults is a rare condition presenting with heterogeneous symptoms. CT scan and transabdominal ultrasonography should be used as diagnostic tools. Nearly all patients underwent surgical treatment with an uneventful follow-up. Complications such as stone formation and altered function of the affected kidney are common. Surgical treatment is recommended and is determined by consideration of age, symptoms, ureteral extension and progressive loss of renal function.
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  • 文章类型: Journal Article
    目的:输尿管膀胱交界处高压球囊扩张术(HPBD)联合双J支架置入术是一种微创的替代输尿管重植术或输尿管皮肤造口术的一线手术治疗原发性梗阻性输尿管(POM)。我们研究的目的是确定由于HPBD失败而需要进行二次手术的风险因素。
    方法:前瞻性数据收集自2007年至2021年在单一机构接受POMHPBD的患者。收集的数据包括患者的人口统计,诊断方式,手术细节,结果,和后续行动。进行多因素logistic回归分析。
    结果:在50名儿童中,有55名输尿管接受了POM的HPBD,年龄中位数为6.4个月(IQR:4.5-13.8)。19例(37.25%)患者接受了二次输尿管再植术,原发性HBPD后的中位数为9.8个月(95%CI6.2-9.9)。中位随访时间为29.4个月(IQR:17.4-71)。在多变量逻辑回归模型中,重做手术的独立危险因素是:进行性输尿管肾积水(OR=7.8;95%CI0.77-78.6)和早期移除双J支架。每额外一天的导管维护观察到风险降低7%(95%CI2.2%-11.4%)。最佳截止点是55天,ROC曲线面积:0.77(95%CI0.62-0.92)。性别,输尿管远端直径,骨盆直径,扩张球囊直径和术前差异肾功能不影响再植的需要。
    结论:使用双J支架至少55天似乎避免了二次手术的需要。因此,我们建议在HBPD后至少2个月取出双J导管.
    OBJECTIVE: High-pressure balloon dilatation (HPBD) of the ureterovesical junction with double-J stenting is a minimally invasive alternative to ureteral reimplantation or cutaneous ureterostomy for first-line surgical treatment of primary obstructive megaureter (POM). The aim of our study was to identify the risk factors associated with the need for secondary procedures due to HPBD failure.
    METHODS: Prospective data were collected from patients who underwent HPBD for POM between 2007 and 2021 at a single institution. The collected data included patient demographics, diagnostic modalities, surgical details, results, and follow-up. Multivariate logistic regression analysis was performed.
    RESULTS: Fifty-five ureters underwent HPBD for POM in 50 children, with a median age of 6.4 months (IQR: 4.5-13.8). Nineteen patients (37.25%) underwent secondary ureteric reimplantation, with a median of 9.8 months after primary HBPD (95% CI 6.2-9.9). The median follow-up was 29.4 months (IQR: 17.4-71). Independent risk factors for redo-surgery in a multivariate logistic regression model were: progressive ureterohydronephrosis (OR = 7.8; 95% CI 0.77-78.6) and early removal of the double-J stent. A risk reduction of 7% (95% CI 2.2%-11.4%) was observed per extra-day of catheter maintenance. The optimal cut-off point is 55 days, ROC curve area: 0.77 (95% CI 0.62-0.92). Gender, distal ureteral diameter, pelvis diameter, dilatation balloon diameter and preoperative differential renal function did not affect the need for reimplantation.
    CONCLUSIONS: The use of a double-J stent for at least 55 days seems to avoid the need for a secondary procedure. Therefore, we recommend removing the double-J catheter at least 2 months after the HBPD.
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  • 文章类型: Journal Article
    目的:比较逆行输尿管软镜(fURS)和后腹腔镜输尿管切开取石术(RLU)治疗输尿管近端大结石的效果。
    方法:一项前瞻性随机试验于2018年1月至2022年12月进行,包括15-25mm输尿管近端结石嵌顿的患者。患者接受fURS或RLU。主要结果是无结石率。人口统计数据,石头特征,并比较两组间的并发症发生率。
    结果:共纳入64例患者,每组32人。两组之间的平均冲击时间相似,以及石材尺寸(17毫米)和石材密度(>1000Hounsfield单位)。两组之间的输尿管无结石率(fURS为93.7%,RLU为96.8%;比值比[OR]0.72,95%置信区间[CI]-1.72至3.17;P=0.554),和整体成功率,其中考虑了肾脏中的残留片段(fURS为84.3%,RLU为93.7%;OR1.02,95%CI-0.69至2.74;P=0.23),是相似的。两组之间的手术时间也没有统计学差异(中位数80vs82分钟;P=0.101)。住院时间没有差异。fURS的逆行率更高(65.6%vs3.1%;p<0.001)。残余肾积水(每组34.3%)和并发症发生率根据治疗方法没有差异。
    结论:柔性URS和RLU对于输尿管近端受累的大结石治疗都是高效且低发病率的。RLU并不优于fURS。
    OBJECTIVE: To compare the outcomes of retrograde flexible ureteroscopy (fURS) with retroperitoneal laparoscopic ureterolithotomy (RLU) for large proximal ureteric stones.
    METHODS: A prospective randomised trial was conducted from January 2018 through December 2022 including patients with impacted proximal ureteric stones of 15-25 mm. Patients underwent fURS or RLU. Primary outcome was the stone-free rate. Demographic data, stone features, and complications rates were also compared between groups.
    RESULTS: A total of 64 patients were enrolled, 32 in each group. The mean impacted stone time was similar between groups, as well as stone size (17 mm) and stone density (>1000 Hounsfield Units). The ureteric stone-free rates between the two groups (93.7% in fURS vs 96.8% in RLU; odds ratio [OR] 0.72, 95% confidence interval [CI] -1.72 to 3.17; P = 0.554), and overall success rates, which take into account residual fragments in the kidney (84.3% in fURS vs 93.7% in RLU; OR 1.02, 95% CI -0.69 to 2.74; P = 0.23), were similar. Operative time was also not statistically significantly different between groups (median 80 vs 82 min; P = 0.101). There was no difference in hospital length of stay. Retropulsion rate was higher with fURS (65.6% vs 3.1%; p < 0.001). Residual hydronephrosis (34.3% each group) and complication rates did no differ according to treatment.
    CONCLUSIONS: Flexible URS and RLU are both highly efficient and present low morbidity for large impacted proximal ureteric stone treatment. RLU is not superior to fURS.
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