ultrasound-guided

超声引导
  • 文章类型: Journal Article
    肌腱病是一种以肌腱障碍为特征的疾病状态,伴有疼痛或功能下降,可导致严重残疾。存在多种治疗方式;然而,没有单一的治疗是优越的。超声引导下经皮穿刺术(PNT)和TENEX正在成为肌腱病的有希望的治疗选择。
    为了回顾目前关于PNT结果报告的文献,TENEX,和TENJET,用于治疗肌腱病,包括疼痛缓解,功能改变,和患者报告的结果。
    从数据库开始到2023年9月在OvidMedline进行了全面搜索,OvidEmbase,科克伦图书馆
    与肌腱损伤相关的关键词和索引术语,超声,和肌腱切开术结合使用,以确定相关文献,包括超声引导,肌腱病的治疗,用PNT治疗,TENEX,或TENJET。用于筛选相关研究的Covidence系统审查软件。只包括英语学习。
    系统审查使用PICO框架定义并在国际前瞻性系统审查注册(PROSPEROIDCRD42022321307)注册。
    第4级(包括从系统评价到最低研究水平的证据)。
    审查了符合纳入标准的文章。研究了肌腱病的类型和区域,结果衡量标准,并记录并发症。在研究中比较了临床和自我报告的结果数据。
    共10项研究,代表11个肌腱部位,包括在内。这些研究总体上报告了疼痛的改善,函数,以及接受PNT或TENEX后的生活质量,最小的不利影响。在纳入研究的评估内部和外部有效性的10个评估中,偏倚评估得分平均为8.35。
    PNT和TENEX是安全的,有益的,和患者的微创治疗选择,特别是对于更保守治疗方案难以治疗的条件。
    UNASSIGNED: Tendinopathy is a disease state characterized by tendon disorder with pain or decreased function that can cause significant disability. Multiple treatment modalities exist; however, no single treatment is superior. Ultrasound-guided percutaneous needle tenotomy (PNT) and TENEX are emerging as promising treatment options for tendinopathy.
    UNASSIGNED: To review the current literature of reported outcomes for PNT, TENEX, and TENJET, for the treatment of tendinopathy, including pain relief, change in function, and patient-reported outcomes.
    UNASSIGNED: A comprehensive search was conducted from database inception to September 2023 in Ovid Medline, Ovid Embase, and Cochrane Library.
    UNASSIGNED: Keywords and index terms related to tendon injury, ultrasound, and tenotomy were used in combination to identify relevant literature that included ultrasound-guidance, treatment of tendinopathy, and treatment with PNT, TENEX, or TENJET. Covidence Systematic Review Software used to screen for relevant studies. Only English-language studies were included.
    UNASSIGNED: Systematic Review using PICO framework as defined and registered with the International Prospective Register of Systematic Reviews (PROSPERO ID CRD42022321307).
    UNASSIGNED: Level 4 (evidence from a systematic review graded to the lowest level of study included).
    UNASSIGNED: Articles meeting the inclusion criteria were reviewed. Type and region of tendinopathy studied, outcome measures, and complications were recorded. Clinical and self-reported outcomes data were compared across studies.
    UNASSIGNED: A total of 10 studies, representing 11 tendon sites, were included. The studies overall report improvements in pain, function, and quality of life after undergoing PNT or TENEX, with minimal adverse effects. Mean risk of bias assessment scores were 8.35 out of 10 assessing internal and external validity for included studies.
    UNASSIGNED: PNT and TENEX are safe, beneficial, and minimally invasive treatment option for patients, especially for conditions refractory to more conservative treatments options.
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  • 文章类型: Journal Article
    背痛是全球残疾的主要原因,并导致严重的医疗和经济负担。硬膜外类固醇注射(ESI)已被广泛用作治疗具有各种病因的神经根病的背痛。与使用荧光透视引导(FG)的当前标准技术相比,用于递送ESI的超声引导(UG)可以在资源有限的环境中降低成本并促进手术。这项范围审查旨在比较UG和FGESI治疗神经根性疼痛的临床结果。Embase的系统搜索,OvidMedline,Scopus,CENTRAL(Cochrane中央受控试验登记册),CDSR(Cochrane系统评价数据库),和ClinicalTrials.gov是根据PRISMA-ScR(系统评价的首选报告项目和范围审查的Meta分析扩展)指南进行的。纳入了随机对照试验(RCT)和比较观察性研究,研究了UG和FGESI治疗神经根性疼痛的结果。使用Cochrane协作偏倚风险工具评估纳入的RCT偏倚风险。从1659个潜在相关出版物中,纳入了8项研究(5项RCT和3项回顾性比较研究).其中五项研究是在大韩民国进行的,一个在中国,一个在印度,一个在埃及。所有研究报告UG和FGESI之间的成功率没有显着差异,疼痛指数,术后残疾(p>0.05)。一项研究报告FG组血管内注射增加,但没有达到统计学意义(p>0.05)。一项研究报告,UG组的针头放置时间减少(p<0.001)。一项研究报告UG组的总手术时间减少(p<0.05)。总的来说,UG和FGESI治疗神经根性疼痛的治疗结局和不良事件情况具有可比性.UGESI降低成本,尽量减少辐射暴露,便于船只识别,防止伤害,并可能节省术中时间,同时提供与FG注射相同的益处。未来的研究应该关注长期结果,成本效益,以及UGESI对患者满意度和生活质量的影响。
    Back pain is the leading cause of disability globally and results in a substantial medical and economic burden. Epidural steroid injections (ESIs) have been widely used as a treatment for back pain with radiculopathy of various etiologies. Ultrasound guidance (UG) for delivering ESIs can reduce costs and facilitate the procedure in resource-limited settings compared to the current standard technique of using fluoroscopic guidance (FG). This scoping review aimed to compare the clinical outcomes between UG and FG ESIs in the treatment of radicular pain. Systematic searches of Embase, Ovid Medline, Scopus, CENTRAL (Cochrane Central Register of Controlled Trials), CDSR (Cochrane Database of Systematic Reviews), and ClinicalTrials.gov were conducted in accordance with PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for scoping reviews) guidelines. Randomized controlled trials (RCTs) and comparative observational studies investigating the outcomes between UG and FG ESIs in the treatment of radicular pain were included. The risk of bias for included RCTs was assessed using the Cochrane Collaboration risk-of-bias tool. From 1,659 potentially relevant publications, eight studies (five RCTs and three retrospective comparative studies) were included. Five of the studies were conducted in the Republic of Korea, one in China, one in India, and one in Egypt. All studies reported no significant difference between UG and FG ESIs in success rate, pain index, and postoperative disability (p > 0.05). One study reported increased intravascular injections in the FG group, but this did not reach statistical significance (p > 0.05). One study reported decreased needle-placement time in the UG group (p < 0.001). One study reported decreased total operation time in the UG group (p < 0.05). Overall, treatment outcomes and adverse events profile are comparable between UG and FG ESIs for radicular pain. UG ESIs reduce costs, minimize radiation exposure, facilitate vessel identification, prevent injury, and potentially save intraoperative time while offering the same benefits as FG injections. Future studies should focus on long-term outcomes, cost-effectiveness, and the impact of UG ESIs on patient satisfaction and quality of life.
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  • 文章类型: Journal Article
    背景:本研究旨在总结超声引导下针刺和干针治疗的研究现状以及应用于患者的具体治疗方法。方法:进行范围审查,调查三个英语数据库(PubMed,Embase,和Cochrane图书馆),用于截至2024年5月发表的研究。考虑了所有与超声引导针灸和干针治疗有关的研究。使用选择和排除标准选择文献,并使用EndNote提取和组织。结果:共纳入107项符合条件的研究。在107项研究中,非比较研究所占比例最大(n=47,43.9%),其次是随机对照试验(RCTs;n=41,38.3%)。肌肉骨骼系统或结缔组织的疾病(肌肉骨骼系统或结缔组织的15种疾病)占研究的86种疾病中的大多数(n=48,55.8%),其次是症状,标志,或未经其他分类的临床状况(n=17,19.8%)。结论:超声引导下的针刺和干针疗法已被积极研究并应用于各种疾病的治疗。然而,在研究和临床实践中的进一步应用需要更高质量的研究。
    Background: This study aimed to summarize the current status of research on ultrasound-guided acupuncture and dry-needling treatment and the specific treatment methods applied to patients. Methods: A scoping review was conducted, surveying three English databases (PubMed, Embase, and the Cochrane Library) for studies published up to May 2024. All studies related to ultrasound-guided acupuncture and dry-needling treatment were considered. Literature was selected using selection and exclusion criteria, and extracted and organized using EndNote. Results: A total of 107 eligible studies were included. Among the 107 studies, non-comparative studies accounted for the largest proportion (n = 47, 43.9%), followed by randomized controlled trials (RCTs; n = 41, 38.3%). Diseases of the musculoskeletal system or connective tissue (15 diseases of the musculoskeletal system or connective tissue) accounted for most (n = 48, 55.8%) of the 86 diseases studied, followed by symptoms, signs, or clinical conditions not otherwise classified (n = 17, 19.8%). Conclusions: Ultrasound-guided acupuncture and dry-needling have been actively studied and applied for the treatment of various diseases. However, higher-quality studies are needed for further applications in research and clinical practice.
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  • 文章类型: Journal Article
    背景:目前,床旁肺部超声的应用逐渐增多,但在围手术期麻醉领域尚无相关专家共识或指导。通过这个荟萃分析,我们试图确定超声引导下的肺复张操作(LRM)对围手术期患者的影响.
    方法:我们搜索了PubMed,Cochrane图书馆数据库,Embase,和截至2022年12月31日发表的随机对照试验(RCT)的临床试验政府。主要结果是术后肺不张的发生率。次要结果包括肺超声评分(LUS)和各部分的LUS。在9项随机对照试验中,共检查了443例患者。
    结果:超声引导下LRM患者术后肺不张的发生率较低(RR0.31;95%CI0.25-0.40;p<0.05)。LUS(WMD-6.24;95%CI-6.90-5.59;p<0.05)和各部位LUS(前肺区域LUS(WMD-2.00;95%CI-2.49至-1.51;p<0.05);侧肺区域LUS(WMD-2.50;95%CI-3.20至-1.80;p<0.05);超声引导下肺区域LUS(WMD-2.24%)
    结论:超声引导下的肺复张操作已被证明是一种有希望的方法,可以通过增加通气量同时减轻肺不张的发展来改善围手术期的肺通气。与非超声引导方法相比,这项技术表现出优异的效果。
    BACKGROUND: At present, the application of bedside lung ultrasound is increasing gradually, but there is no relevant expert consensus or guidance for its evaluation in the field of perioperative anesthesia. Through this meta-analysis, we tried to determine the impact of ultrasound-guided lung recruitment maneuvers (LRM) on perioperative patients.
    METHODS: We searched PubMed, Cochrane Library database, Embase, and Clinical Trials gov for the randomized controlled trials (RCTs) published up to December 31, 2022. The primary outcome was the incidence of postoperative atelectasis. Secondary outcomes included lung ultrasound score (LUS) and LUS of each part. A total of 443 patients were examined in nine randomized controlled trials.
    RESULTS: The incidence of atelectasis after surgery in patients with ultrasound-guided LRM was less (RR 0.31; 95% CI 0.25-0.40; p < 0.05). The LUS (WMD - 6.24; 95% CI - 6.90-5.59; p < 0.05) and the LUS of each part (LUS in front lung region (WMD - 2.00; 95% CI - 2.49 to - 1.51; p < 0.05); LUS in lateral lung region (WMD - 2.50; 95% CI - 3.20 to - 1.80; p < 0.05); LUS in posterior lung region (WMD - 3.24; 95% CI - 4.23 to - 2.24; p < 0.05)) in patients with ultrasound-guided LRM were lower.
    CONCLUSIONS: Ultrasound-guided lung recruitment maneuvers have been shown to be a promising approach for improving perioperative lung ventilation by increasing aeration while mitigating the development of atelectasis. In comparison to non-ultrasound-guided methods, this technique has exhibited superior effects.
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  • 文章类型: Journal Article
    常见的伸肌腱病是肘部外侧疼痛的常见原因。超声引导下微创肌腱切开术(MIT)已被成功地用作治疗多年,但是TenJet设备的使用并没有得到很好的描述。
    评估TenJet在门诊环境中对常见伸张肌腱病的非手术治疗失败的MIT的有效性和安全性。
    共有100例保守治疗失败的普通伸肌腱病患者在一个机构的门诊环境中接受了超声引导的MIT和TenJet设备。MIT之前的所有100例患者均接受了诊断性肌肉骨骼超声检查,显示常见的伸肌肌腱病。研究结果由受过研究金训练和董事会认证的肌肉骨骼放射科医生解释。在手术前和随访1年时,对患者进行了牛津肘部评分评估。排除标准包括在MIT干预的过去6周内之前的皮质类固醇注射,活动性局部或全身感染,总伸肌腱完全全厚度撕裂,和怀孕。
    OxfordElbow评分在基线至1年有统计学上的显著差异(P<.001)。未报告并发症,零患者继续需要开放式手术干预。
    与TenJet的MIT是安全的,有效,和耐受性良好的治疗常见的伸肌腱病。
    UNASSIGNED: Common extensor tendinopathy is a common cause of lateral elbow pain. Ultrasound-guided minimally invasive tenotomy (MIT) has been utilized successfully as a treatment for several years, but the use of TenJet device has not been well described.
    UNASSIGNED: To evaluate the effectiveness and safety of MIT with TenJet who failed nonsurgical management of common extensor tendinopathy in an outpatient setting.
    UNASSIGNED: A total of 100 patients with common extensor tendinopathy who failed conservative treatment underwent ultrasound-guided MIT with TenJet device in the outpatient setting at a single institution. All 100 patients prior to MIT underwent diagnostic musculoskeletal ultrasound showing common extensor tendinosis. The findings were interpreted by a fellowship-trained and board-certified musculoskeletal radiologist. Patients were evaluated with the Oxford Elbow Score prior to the procedure and at 1-year follow-up. Exclusion criteria included prior corticosteroid injection within the past 6 weeks of the MIT intervention, active local or systemic infection, complete full thickness tear of the common extensor tendon, and pregnancy.
    UNASSIGNED: Oxford Elbow Score had a statistically significant difference in baseline to 1 year (P < .001). No complications were reported and zero patients went on to require open surgical intervention.
    UNASSIGNED: MIT with TenJet is a safe, effective, and well-tolerated treatment for common extensor tendinopathy.
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  • 文章类型: Systematic Review
    对报告使用超声注射类固醇治疗deQuervain的研究进行了系统评价。包括10项研究和379个手腕,73.9%报告症状完全缓解,部分18.2%,无分辨率7.9%。与地标引导技术相比,超声引导显示明显更高的症状缓解率(P=0.0132)和更低的疼痛评分(P<0.0001).在163名最初表现出症状完全缓解的患者中,有29名患者报告了随后的复发。我们得出的结论是,通过精确的针头插入,超声引导下的类固醇注射可提供较高的症状缓解率,尤其是在具有亚隔室的解剖变异性的情况下。
    A systematic review was conducted on studies reporting steroid injections with ultrasound for de Quervain. From 10 studies included and 379 wrists, 73.9% reported complete resolution of symptoms, 18.2% with partial and 7.9% without resolution. When compared to the landmark-guided technique, ultrasound guidance showed significantly higher rates of symptom resolution (P = 0.0132) and lower pain scores (P < 0.0001). Twenty-nine patients out of 163 who initially showed complete resolution of symptoms reported subsequent recurrence. We conclude that steroid injections guided by ultrasound present high rates of symptomatic relief through precise needle insertion, especially in cases of anatomic variability with subcompartments.
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  • 文章类型: Systematic Review
    背景:两种最常见的超声引导动脉插管方法是长轴平面内(LA-IP)和短轴平面外(SA-OOP)方法。然而,不确定哪种方法更有利。我们对报道的随机临床试验(RCT)进行了荟萃分析,比较了两种技术的成功率,插管时间,和并发症。
    方法:我们系统地搜索了PubMed,Embase,和CochraneLibrary数据库的RCT数据库,比较了LA-IP和SA-OOP技术在超声引导下动脉插管术中的应用,从开始到2022年4月31日。使用Cochrane协作的偏差风险工具来评估每个RCT的方法学质量。ReviewManager5.4和Stata/SE17.0用于分析两个主要结局指标(首次尝试成功率和总成功率)和两个次要结局指标(插管时间和并发症)。
    结果:共纳入13项RCTs,1,377例患者。首次尝试成功率没有显著差异(风险比[RR],0.93;95%置信区间[CI],0.78-1.12;P=0.45;I2=84%)和总体成功率(RR,0.99;95%CI,0.95-1.02;P=0.48;I2=57%)。与LA-IP技术相比,SA-OOP技术与后壁穿刺发生率增加相关(RR,3.01;95%CI,1.27-7.14;P=0.01;I2=79%)和血肿(RR,2.15;95%CI,1.05-4.37;P=0.04;I2=63%)。技术之间的血管痉挛发生率没有显着差异(RR,1.26;95%CI,0.37-4.23;P=0.07;I2=53%)。
    结论:目前的结果表明,SA-OOP技术比LA-IP技术具有更高的后壁穿刺和血肿发生率,而两种超声引导动脉插管技术的成功率相似。由于RCT间的异质性较高,因此应以更严格的方式对这些发现进行实验评估。
    The two most common methods for ultrasound-guided arterial cannulation are the long-axis in-plane (LA-IP) and short-axis out-of-plane (SA-OOP) approaches. However, it is uncertain which method is more advantageous. We conducted a meta-analysis of reported randomized clinical trials (RCTs) comparing the two techniques in terms of success rate, cannulation time, and complications.
    We systematically searched PubMed, Embase, and the Cochrane Library database for RCTs comparing the LA-IP and SA-OOP techniques for ultrasound-guided arterial cannulation published from inception through April 31, 2022. The Cochrane Collaboration\'s Risk of Bias Tool was used to evaluate the methodological quality of each RCT. Review Manager 5.4 and Stata/SE 17.0 were used to analyze the two primary outcome measures (first-attempt success rate and total success rate) and two secondary outcome measures (cannulation time and complications).
    A total of 13 RCTs with 1,377 patients were included. There were no significant differences in first-attempt success rate (risk ratio [RR], 0.93; 95% confidence interval [CI], 0.78-1.12; P = 0.45; I2 = 84%) and overall success rate (RR, 0.99; 95% CI, 0.95-1.02; P = 0.48; I2 = 57%). When compared with the LA-IP technique, the SA-OOP technique was associated with an increased incidence of posterior wall puncture (RR, 3.01; 95% CI, 1.27-7.14; P = 0.01; I2 = 79%) and hematoma (RR, 2.15; 95% CI, 1.05-4.37; P = 0.04; I2 = 63%). There was no significant difference in the incidence of vasospasm between techniques (RR, 1.26; 95% CI, 0.37-4.23; P = 0.07; I2 = 53%).
    The present results suggest that the SA-OOP technique is associated with a higher incidence of posterior wall puncture and hematoma than the LA-IP technique, whereas success rates are similar for the two ultrasound-guided arterial cannulation techniques. These findings should be experimentally evaluated in a more rigorous manner due to high inter-RCT heterogeneity.
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  • 文章类型: Journal Article
    腕管综合征(CTS)是最常见的外周卡压,最近,超声引导下的神经周注射(UPIT)和经皮屈肌支持带释放(UPCTR)已用于治疗CTS。然而,没有系统评价或荟萃分析包括两种介入类型的CTS超声引导介入治疗.因此,我们使用四个数据库(即,PubMed,EMBASE,Scopus,和Cochrane)来评估证据的质量,有效性,以及已发表的CTS超声引导干预研究的安全性。在选择进行系统审查的60项研究中,20项随机治疗比较或对照研究包括在6项荟萃分析中。具有超声引导的类固醇UPIT优于具有地标引导的类固醇UPIT。高剂量类固醇的UPIT优于低剂量类固醇。含有5%葡萄糖水溶液(D5W)的UPIT优于对照注射,而高体积D5W的水解剖优于低体积D5W。具有富血小板血浆的UPIT优于各种对照治疗。就症状改善而不是功能改善而言,UPCTR优于开放手术。在审查的研究中没有严重不良事件的报告。研究结果表明,UPIT和UPCTR都可以提供临床上重要的益处,并且看起来很安全。需要进一步的治疗比较研究来确定比较疗效。
    Carpal tunnel syndrome (CTS) is the most common peripheral entrapment, and recently, ultrasound-guided perineural injection (UPIT) and percutaneous flexor retinaculum release (UPCTR) have been utilized to treat CTS. However, no systematic review or meta-analysis has included both intervention types of ultrasound-guided interventions for CTS. Therefore, we performed this review using four databases (i.e., PubMed, EMBASE, Scopus, and Cochrane) to evaluate the quality of evidence, effectiveness, and safety of the published studies on ultrasound-guided interventions in CTS. Among sixty studies selected for systemic review, 20 randomized treatment comparison or controlled studies were included in six meta-analyses. Steroid UPIT with ultrasound guidance outperformed that with landmark guidance. UPIT with higher-dose steroids outperformed that with lower-dose steroids. UPIT with 5% dextrose in water (D5W) outperformed control injection and hydrodissection with high-volume D5W was superior to that with low-volume D5W. UPIT with platelet-rich plasma outperformed various control treatments. UPCTR outperformed open surgery in terms of symptom improvement but not functional improvement. No serious adverse events were reported in the studies reviewed. The findings suggest that both UPIT and UPCTR may provide clinically important benefits and appear safe. Further treatment comparison studies are required to determine comparative therapeutic efficacy.
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  • 文章类型: Meta-Analysis
    目的:评估超声引导在宫内节育器(IUD)置入过程中缓解疼痛的效果。
    方法:从开始到2022年6月搜索了四个不同的数据库。我们选择了随机对照试验(RCTs),比较了在接受宫内节育器放置避孕的妇女中,经腹超声引导与传统的非引导宫内节育器插入。我们在进行荟萃分析时使用了Revman软件。我们的主要结果是通过视觉模拟量表(VAS)评估的IUD插入过程中的疼痛评分。我们的次要结果是手术插入时间,满意,并发症和错位宫内节育器的发生率。
    结果:共检索到7个随机对照试验,共1267例患者。在超声引导下的IUD插入期间,VAS疼痛评分显着降低(MD=-1.91,95%CI[-3.08,-0.73],P=.001)。超声引导组插入手术时间明显短于对照组(MD=-1.35,95%CI[-1.81,-0.88],P<.001)。此外,在超声引导组患者中,更多的女性对手术方式满意(P<.001).此外,超声引导下的宫内节育器插入与并发症和错位宫内节育器的发生率显着下降有关.
    结论:在宫内节育器插入期间,超声引导可以作为一种改进的技术,因为它可以减轻疼痛,程序时间,以及并发症和错位宫内节育器的发生率,患者满意度更高。
    OBJECTIVE: To evaluate ultrasound guidance effect in pain relief during intrauterine device (IUD) insertion.
    METHODS: Four different databases were searched from inception till June 2022. We selected randomized controlled trials (RCTs) that compared transabdominal ultrasound guidance versus traditional non-guided IUD insertion among women undergoing IUD placement for contraception. We used Revman software during performing our meta-analysis. Our primary outcome was the pain score during IUD insertion as evaluated by the Visual Analog Scale (VAS). Our secondary outcomes were the procedure insertion time, satisfaction, and incidences of complications and misplaced IUDs.
    RESULTS: Seven RCTs were retrieved with a total number of 1267 patients. There was a significant reduction in the VAS pain score during IUD insertion among the ultrasound-guided group (MD = -1.91, 95% CI [-3.08, -0.73], P = .001). The procedure insertion time was significantly shorter within the ultrasound guidance group compared with the control group (MD = -1.35, 95% CI [-1.81, -0.88], P < .001). Moreover, more women were significantly satisfied with the procedure among the ultrasound-guided group (P < .001). In addition, ultrasound-guided IUD insertion was linked to significant decline in incidences of complications and misplaced IUDs.
    CONCLUSIONS: Ultrasound guidance can be used as a modified technique during IUD insertion as it decreases pain, procedure time, and rates of complications and misplaced IUDs with better patient satisfaction.
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  • 文章类型: Journal Article
    UNASSIGNED:我们通过系统评价和荟萃分析,全面评估了超声引导下射频消融(RFA)治疗甲状腺乳头状微小癌(PTMC)的疗效和安全性。
    未经授权:我们搜索了PubMed,Embase和Cochrane图书馆数据库,用于在数据库建立到2021年10月之间的时间内发表的研究。我们纳入了10项非随机对照试验(非RCT),报道了美国指导RFA在PTMC中的应用。患者的样本量总计为1279。我们通过分析体积减少率(VRR)来评估消融疗效,RFA治疗PTMC的完全消失率(CDR)和复发率。我们使用STATA15.1版分析了所有数据(Stata公司,学院站,TX)。
    UNASSIGNED:我们的汇总结果证明RFA治疗可显着减少肿瘤体积(加权平均差[WMD]=-103.20,95%CI:-111.93--94.48,p=0.000)。我们还发现RFA后12个月的VRR为93.27%(95%CI:84.68-101.86),RFA后12个月的CDR为64%(95%CI:39-89%)。此外,汇总结果显示消融区mPTC残留的发生率,RFA治疗后新发现的mPTC和淋巴结转移分别为0.3%(95%CI:-0.1-0.7%),2.5%(95%CI:1.1-3.9%)和1.0%(95%CI:0.2-1.9%),RFA治疗后并发症发生率为1.8%(95%CI:0.7-3.2%)。
    未经授权:美国指导的RFA治疗PTMC是安全有效的。它可能是现有治疗方案的绝佳替代方案。
    We comprehensively evaluate the efficacy and safety of US-guided radiofrequency ablation (RFA) in the treatment of papillary thyroid microcarcinoma (PTMC) via a systematic review and meta-analysis.
    We searched the PubMed, Embase and Cochrane Library databases for studies published during the time between the establishment of the database through October 2021. We included a 10 non-randomized controlled trial (non-RCT) that reported the application of US-guided RFA in PTMC. The sample size of patients totaled 1279. We evaluated the ablation efficacy by analyzing the volume reduction rate (VRR), complete disappearance rate (CDR) and recurrence rate of PTMC treated by RFA. We analyzed all data using STATA version 15.1 (Stata Corporation, College Station, TX).
    Our pooled results proved RFA treatment significantly reduces the volume of tumors (Weighted Mean Difference [WMD] = -103.20, 95% CI: -111.93 - -94.48, p = 0.000). We also found the VRR at 12 months after RFA was 93.27% (95% CI: 84.68-101.86), and the CDR at 12 months after RFA was 64% (95% CI: 39-89%). Additionally, pooled results showed the incidence of mPTC residue in ablation area, newly discovered mPTC and lymph node metastases after RFA treatment were respectively 0.3% (95% CI: -0.1-0.7%), 2.5% (95% CI: 1.1-3.9%) and 1.0% (95% CI: 0.2-1.9%), and the incidence of complications after RFA treatment was 1.8% (95% CI: 0.7-3.2%).
    US-guided RFA is effective and safe for treating PTMC. It could be an excellent alternative to the existing treatment options.
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