total hip replacement

全髋关节置换
  • 文章类型: Journal Article
    背景:择期全髋关节置换术后静脉血栓栓塞是公认的并发症,导致致命的肺栓塞,血栓形成后综合征和血栓复发。临床组织制定的指南试图为临床医生提供循证建议。
    方法:这篇叙述性综述评估了与现有指南相关的现有文献,评估当前的主要指南是否反映了证据基础。所有主要临床指南都通过数据库搜索进行了整理,相关的临床研究。
    结果:多模态方法的推广,机械和化学预防相结合,似乎得到了很好的验证,机械预防提供积极的临床效果,几乎没有负面的临床后果。在目前关于选择性THA患者VTE预防的指南中,在风险分层和针对特定患者亚组采用个性化方法方面,似乎缺乏处方.
    结论:我们建议放弃预防VTE的协议,鉴于证据基础还没有完全发展到允许“一刀切”的方法。
    BACKGROUND: Venous Thromboembolism after elective Total Hip Arthroplasty surgery is a well-recognised complication, resulting in fatal pulmonary embolism, post thrombotic syndrome and recurrent thrombotic episodes. Guidelines developed by clinical organisations attempt to provide evidence-based recommendations to clinicians.
    METHODS: This narrative review evaluated the current available literature in relation to the available guidelines, to evaluate whether the current major guidelines reflect the evidence base. All major clinical guidelines were collated through database searching, alongside the relevant clinical studies.
    RESULTS: The promotion of a multi-modal approach, combining mechanical and chemical prophylaxis, does appear to be well validated, with mechanical prophylaxis offering positive clinical effects with little negative clinical consequence. Within the current guidelines surrounding VTE prevention in the elective-THA patient, there does appear to be a lack of prescription in relation to risk stratification and adopting personalised approaches for specific patient subsets.
    CONCLUSIONS: We suggest moving away from protocolisation of VTE prevention, given the evidence base is not fully developed to allow a \'one-size-fits-all\' approach.
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  • 文章类型: Journal Article
    假体周围关节感染(PJI)是全髋关节和膝关节置换术中的破坏性并发症。预防是降低发病率和避免一些严重影响患者和卫生系统的后果的关键。鉴于各种建议和准则,我们决定聘请专家,同行评审的欧洲共识分析,intra-,术后预防PJI。一个跨国骨科执业专家小组在6个主要干预组中制定了一系列47个共识声明,和一个2阶段的德尔福方法推出了协议的阈值在75%和非常高的协议在90%以上。总共收集了来自9个国家的306名整形外科医生的回复。就42/47项声明达成共识,第31/47号决议达成了非常高的共识。许多术前行动聚集了强烈的共识,尽管使用含酒精的氯己定或脱毛时机等领域并未达成强烈共识,尽管有证据。手术前后的动作表现出更多的可变性,皮肤缝合技术,和伤口随访。这项研究证实了欧洲整形外科医生在许多众所周知的有助于预防PJI的地区达成的重要共识;然而,仍有改进的理由。
    Periprosthetic joint infection (PJI) is a devastating complication in total hip and knee replacement. Its prevention is key to decrease the incidence and avoid some consequences that seriously impact patients and health systems. In view of the variety of recommendations and guidelines, we decided to conduct an expert, peer-reviewed European consensus analysis about the pre-, intra-, and postoperative prevention of PJI. A multinational group of practicing orthopedic experts developed a series of 47 consensus statements in 6 main groups of intervention, and a 2-stage Delphi approach was launched with a threshold for agreement at 75% and for very high agreement at more than 90%. A total of 306 orthopedic surgeon responses were gathered from 9 countries. Consensus was reached for 42/47 statements, 31/47 of which achieved a very high consensus. Many preoperative actions gathered strong consensus, although areas like the use of alcoholic chlorhexidine or the timing of hair removal did not attain strong consensus, despite available evidence. Intra- and postoperative actions showed more variability regarding incise drapes, skin suturing techniques, and wound follow-up. This study confirms an important consensus among orthopedic surgeons across Europe in many areas well known to contribute to the prevention of PJI; however, there are still grounds for improvement.
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  • 文章类型: Journal Article
    背景:我们评估了外科医生对全髋关节置换术(THR)和全膝关节置换术(TKR)的静脉血栓栓塞(VTE)化学预防的实践,在2018年发布最新的国家健康与护理卓越研究所(NICE)指南之前和之后。
    方法:一项调查,通过英国髋关节协会和区域受训者网络/合作者传播,由306名英国外科医生在187个单位完成。在发表2018年NICE建议后,评估了在低风险患者中进行原发性THR(n=258)和TKR(n=253)的外科医生的VTE化学预防处方模式。随后探索了NICE出版物之前和之后的处方模式。
    结果:遵循新指南,34%(n=87)单独使用低分子量肝素(LMWH),33%(n=85)阿司匹林(通常在LMWH之前)和31%(n=81)直接口服抗凝剂(DOACs:有/无LMWH)用于THR。对于TKR,42%(n=105)使用阿司匹林(通常是单药治疗),31%(n=78)单独的LMWH和27%(n=68)DOAC(有/没有先前的LMWH)。NICE指南改变了34%的髋关节外科医生和41%的膝关节外科医生的做法,在使用LMWH治疗THR之前,阿司匹林的使用量显着增加(前=25%,后=73%;p<0.001),阿司匹林治疗TKR(前=18%,后=84%;p<0.001)。在2018年THR(前=85.7%vs后=92.6%;p=0.011)和TKR(前=87.0%vs后=98.8%;p<0.001)更新后,NICE指导依从性明显更高。
    结论:超过三分之一的接受调查的外科医生根据2018年NICE建议改变了他们的VTE化学预防措施。更多的THR和TKR外科医生现在符合最新的NICE指南。实践中的主要变化是增加了阿司匹林用于VTE化学预防。
    BACKGROUND: We assessed the practice of surgeons regarding venous thromboembolism (VTE) chemical prophylaxis for total hip replacement (THR) and total knee replacement (TKR), before and after issuing of updated National Institute for Health and Care Excellence (NICE) guidance in 2018.
    METHODS: A survey, circulated through the British Hip Society and regional trainee networks/collaboratives, was completed by 306 UK surgeons at 187 units. VTE chemical prophylaxis prescribing patterns for surgeons carrying out primary THR (n=258) and TKR (n=253) in low-risk patients was assessed after publication of 2018 NICE recommendations. Prescribing patterns before and after the NICE publication were subsequently explored.
    RESULTS: Following the new guidance, 34% (n=87) used low-molecular-weight heparin (LMWH) alone, 33% (n=85) aspirin (commonly preceded by LMWH) and 31% (n=81) direct oral anticoagulants (DOACs: with/without preceding LMWH) for THR. For TKR, 42% (n=105) used aspirin (usually monotherapy), 31% (n=78) LMWH alone and 27% (n=68) DOAC (with/without preceding LMWH). NICE guidance changed the practice of 34% of hip surgeons and 41% of knee surgeons, with significantly increased use of aspirin preceded by LMWH for THR (before=25% vs after=73%; p<0.001), and aspirin for TKR (before=18% vs after=84%; p<0.001). Significantly more regimens were NICE guidance compliant after the 2018 update for THR (before=85.7% vs after=92.6%; p=0.011) and TKR (before=87.0% vs after=98.8%; p<0.001).
    CONCLUSIONS: Over one-third of surveyed surgeons changed their VTE chemical prophylaxis in response to 2018 NICE recommendations, with more THR and TKR surgeons now compliant with latest NICE guidance. The major change in practice was an increased use of aspirin for VTE chemical prophylaxis.
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  • 文章类型: Journal Article
    初级全髋关节置换术(THA)是一种常见且成功的手术,骨科学员必须在完成手术训练之前证明其能力。从未进行过手术培训师之间关于主要THA关键步骤的协议评估。这项研究的目的是定义和排名主要THA的关键步骤,这些步骤涉及易于教学及其在实现最佳患者结果方面的重要性。
    使用具有3个迭代轮的Delphi技术来建立专家组共识。对于THR的每个步骤,共识的基准在任何类别中都设定为80%的协议。类别内相关系数(ICC)分别用于报告第2轮和第3轮参与者之间和内部评估者之间的可靠性。
    50名骨科顾问髋关节外科医生完成了第2轮,28名完成了第3轮。总的来说,确定了27个步骤(54个参数),16个参数对患者预后的影响达成共识,和17,便于教学。在第2轮和第3轮中,患者预后参数的评估者之间的ICC分别为0.89和0.92,而在教学参数中,则为0.82和0.73。50%的外科医生同意髋臼扩孔,评估和准确恢复腿的长度,髋臼杯前倾是教学员最困难的3个步骤,而90%的人认为这3个步骤对患者预后非常重要。另外5个步骤就其对患者预后的实质性影响达成共识,但未能达成共识以易于教学。
    此专家共识的结果产生了主要THA中关键步骤的排序列表,可用于骨科课程开发,并指导主要THR手术培训的重点改进,包括模拟。
    UNASSIGNED: Primary total hip arthroplasty (THA) is a commonly performed and successful operation which orthopaedic trainees must demonstrate competence in prior to completion of surgical training. An assessment of agreement between surgical trainers regarding the critical steps of a primary THA has never been undertaken. The aim of this study was to define and rank the key steps of a primary THA regards ease of teaching and their importance in achieving the best patient outcome.
    UNASSIGNED: The Delphi technique with 3 iterative rounds was used to establish expert group consensus. The benchmark for consensus was set at an 80% agreement in any category for each step of a THR. The intra-class correlation coefficient (ICC) was used to report on the inter- and intra-rater reliabilities between and within participants responses respectively in rounds 2 and 3.
    UNASSIGNED: 50 consultant orthopaedic hip surgeons completed round 2, and 28 completed round 3. Overall, 27 steps (54 parameters) were identified, with 16 parameters achieving consensus agreement for their impact on patient outcome, and 17 for ease of teaching. The inter-rater ICC for patient outcome parameters was 0.89 and 0.92 in rounds 2 and 3 respectively while for teaching parameters it was 0.82 and 0.73. 50% of surgeons agreed that acetabular reaming, assessing and accurately restoring leg length, and acetabular cup anteversion were the 3 most difficult steps to teach trainees, while 90% agreed these 3 steps were substantially important to patient outcome. Another 5 steps achieved consensus for their substantial impact on patient outcome but failed to achieve consensus for ease of teaching.
    UNASSIGNED: The results of this expert consensus have produced a rank-order list of the key steps in primary THA, which may be used for orthopaedic curriculum development and guiding focused improvements for surgical training in primary THR including simulation.
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  • 文章类型: Journal Article
    BACKGROUND: According to the National Hip Fracture Database (NHFD), in 2018 31.4% of patients with displaced intracapsular neck of femur (NOF) fracture who, National Institute for Health and Care Excellence (NICE) viewed eligible for total hip replacement (THR), received this operation. We aimed to identify the compliance of performing THR for those patients in our unit and identify the reasons for proceeding with the alternative type of surgery.
    METHODS: A five-year retrospective review of eligible patients was conducted between January 2014 and Dec 2018. Statistical analysis was performed between groups who did or didn\'t receive THR. Reasons for not performing THR were identified from pre-operative ward rounds notes.
    RESULTS: In 2018 our unit performed THR for 44% of eligible cases. This was the highest result over five-years and higher than the national average. Out of the 348 eligible cases, pathological or undisplaced intracapsular fractures were excluded. Reminder received THR (138), hip hemiarthroplasty (166) or internal fixation (11). The average age was 77. Younger patients were more likely to receive THR than 80 years or older (p<0.05). THR group scored 0.4 points higher on AMTS and 0.2 lower on ASA scale then non-THR group (9.8 vs. 9.4 and 2.7 vs. 2.5 respectively). Mean time to surgery was 1.24 days with no significant difference between THR and non-THR group (1.6 vs. 1.1) but a slight delay to surgery during the weekends was noted (1.3 vs 1.8 days). Reasons for not performing THR were well documented as a combination of mobility restrictions and serious medical comorbidities. Retrospectively we judged the surgical decision making to be correct in 95% of cases.
    CONCLUSIONS: Annual NHFD report comments on poor national and individual hospital\'s compliance with NICE guidelines without allowing surgeons to justify their choice of the procedure undertaken. Surgical decisions are made in a highly specialised multi-disciplinary environment taking into consideration individual patient\'s frailty and potential morbidity. Details of those discussions should be collected in NHFD to allow further analysis of reasons why surgeons decide not to offer THR to a patient NHFD views as eligible for this procedure. This could help in understanding the complex factors impacting on decision making in those cases.
    METHODS: Level III.
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  • 文章类型: Journal Article
    暂无摘要。
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    文章类型: Journal Article
    BACKGROUND: One of the most critical points in the planning of hip replacement surgeries is the selection of the implant, since its survival significantly impacts the patients health. However, the ideal survival time that an implant must prove to be selected has not been defined. The objective of this consensus is to define minimum performance standards for the selection of conventional primary hip replacement prosthesis.
    METHODS: The consensus was carried out using the methodology of nominal group. This included: 1. A review of the available evidence and the issues to be evaluated, 2. Meeting for the vote and discussion, 3. Quantitative statistical analysis with median (M) and interquartile range (IQR) and qualitative one with proportions of the results to generate recommendations.
    RESULTS: The primary source of information for prosthesis selection (M: 8; IQR: 7-9), choice in the event of conflicting evidence (M: 8; IQR: 7-9), or limited evidence in the literature (M: 7; IQR: 4.75-825) should be national registries. The minimum acceptable follow-up is 10 years (M: 9; IQR: 8-9) and the minimum acceptable survival is 90% at 10 years (M: 8; IQR: 5-8.5).
    CONCLUSIONS: According to these results, the consensus of experts proposed that the selection of the implant for conventional primary hip replacement must be based on the information published in the national registries and that the prosthesis must have a minimum follow-up of 10 years and show a minimum survival of 90%.
    UNASSIGNED: Uno de los puntos más críticos en la planeación de las artroplastías de cadera es la selección del implante, puesto que su supervivencia impacta significativamente la salud de los pacientes. Sin embargo, hasta el momento no se ha definido cuál es la supervivencia ideal que debe demostrar un implante para ser seleccionado. El objetivo de este consenso es definir los estándares mínimos de desempeño para la selección de prótesis en reemplazo primario convencional de cadera.
    UNASSIGNED: El consenso se realizó mediante la metodología de «grupo nominal». Esto incluyó: 1. Revisión de la evidencia disponible y definición de los temas a evaluar, 2. Reunión para la votación y discusión y 3. Análisis estadístico cuantitativo con medianas (M) y rangos intercuartílicos (RIC) y cualitativo con proporciones de los resultados obtenidos para generar recomendaciones.
    UNASSIGNED: La fuente primaria de información para la selección de prótesis (M: 8; RIC: 7-9) y de elección en caso de evidencia contradictoria (M: 8; RIC: 7-9) o limitada en la literatura (M: 7; RIC: 4.75-825) son los registros nacionales. El mínimo seguimiento aceptable es 10 años (M: 9; RIC: 8-9) y el mínimo de supervivencia aceptable es 90% a 10 años (M: 8; RIC: 5-8.5).
    UNASSIGNED: De acuerdo con estos resultados, el consenso de expertos propone que la selección del implante en el reemplazo articular primario convencional de cadera se realice con base en la información publicada en los registros nacionales y que dicha prótesis tenga un seguimiento mínimo de 10 años y demuestre una supervivencia mínima de 90%.
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  • 文章类型: Consensus Development Conference
    背景:在德国,成人非创伤性股骨头缺血性坏死(AVN;N-ANFH)的治疗每年估计发病率为5000-7000例仍然是一个挑战。危险因素包括类固醇,酗酒,化疗和免疫抑制药物,但是有人提出了遗传倾向。这种通常是双侧疾病过程的早期诊断对于成功的保守或保留关节的手术治疗至关重要。在这次审查中,我们将最新的德国共识S3指南“N-ANFH的诊断和管理”作为简明摘要。
    方法:本系统综述基于1970年1月1日至2013年4月31日的已发表文献(德语和英语)。纳入标准是系统评价,荟萃分析和相关同行评审出版物。我们确定了总共3715种相关出版物,其中422个符合SIGN标准,但只有159个符合我们的入选标准。
    结论:临床怀疑N-ANFH需要进行影像学评估。如果X光片是正常的,建议进行MRI扫描,应根据ARCO分类进行评估。鉴别诊断包括短暂性骨质疏松症,骨头瘀伤,功能不全骨折和破坏性关节病。未治疗,软骨下骨折通常发生在2年内,在此期间,对侧受累的风险很高,此后不太可能。可以尝试使用Ilomedin和Alendronat进行保守管理,但是其他药物或物理治疗是不合适的。没有特定的关节保留程序可以推荐,但如果坏死<30%,应在早期阶段考虑核心减压。在ARCOIIIc或IV期应考虑全髋关节置换术(THA),与骨关节炎相比,它提供了相似的结果。年轻年龄是N-ANFHTHA后较高修订率的主要危险因素。
    BACKGROUND: The treatment of adult non-traumatic avascular necrosis of the femoral head (AVN; N-ANFH) within an estimated incidence of 5000-7000 cases per annum in Germany remains a challenge. Risk factors include steroids, alcohol abuse, chemotherapy and immunosuppressive medication, but a genetic predisposition has been suggested. Early diagnosis of this often bilateral disease process is essential for successful conservative or joint preserving surgical management. In this review, we present the update German consensus S3 guideline \"diagnosis and management for N-ANFH\" as a concise summary.
    METHODS: This systematic review is based on the published literature from January 1, 1970 to April 31, 2013 (German and English language). Inclusion criteria were systematic reviews, meta-analyses and relevant peer review publications. We identified a total of 3715 related publications, of which 422 were suitable according to the SIGN criteria, but only 159 fulfilled our inclusion criteria.
    CONCLUSIONS: Clinical suspicion of N-ANFH mandates radiographic evaluation. If radiographs are normal MRI scans are recommended, which should be evaluated according to the ARCO-classification. Differential diagnoses include transient osteoporosis, bone bruise, insufficiency fracture and destructive arthropathy. Untreated, subchondral fractures commonly occur within 2 years, during which the risk for contralateral involvement is high-thereafter unlikely. Conservative management with Ilomedin and Alendronat can be tried, but other pharmacological or physical treatments are inappropriate. No specific joint preserving procedure can be recommended, but core decompression should be considered in early stages if necrosis is <30 %. In ARCO stages IIIc or IV total hip arthroplasty (THA) should be contemplated, which offers similar outcome compared to osteoarthritis. Young age is the main risk factor for higher revision rates after THA for N-ANFH.
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