背景:肩袖病是普通人群的常见病,但对其相关危险因素知之甚少。
方法:我们使用健康改善网络数据库进行了一项大型病例对照研究,以评估和量化一些体质和环境危险因素对社区肩袖疾病的相对贡献。我们的数据集包括5000例肩袖疾病患者,这些患者按年龄分别与单个对照相匹配,性别,和普通实践(初级保健实践)。
结果:诊断时的中位年龄为55岁(四分位距,44-65岁)。多因素分析显示,肩袖疾病的危险因素为跟腱炎(比值比[OR]=1.78),触发手指(OR=1.99),外上髁炎(OR=1.71),腕管综合征(OR=1.55)。口服皮质类固醇治疗(OR=2.03),口服抗糖尿病药物(OR=1.66),胰岛素使用(OR=1.77),和“超重”体重指数25.1至30(OR=1.15)也显着相关。当前或以前的吸烟史,体重指数大于30,任何酒精摄入量,内上髁炎,deQuervain综合征,肘管综合征,类风湿性关节炎未发现与肩袖疾病相关。
结论:我们已经确定了肩袖疾病的一些合并症和危险因素。这些包括外上髁炎,腕管综合征,触发手指,跟腱炎,口服皮质类固醇,和糖尿病。这些发现应提醒临床医生注意病理过程的合并症,并指导未来对这种疾病病因的研究。
BACKGROUND: Rotator cuff disease is a common condition in the general population, but relatively little is known about its associated risk factors.
METHODS: We have undertaken a large
case-control study using The Health Improvement Network database to assess and to quantify the relative contributions of some constitutional and environmental risk factors for rotator cuff disease in the community. Our data set included 5000 patients with rotator cuff disease who were individually matched with a single control by age, sex, and general practice (primary care practice).
RESULTS: The median age at diagnosis was 55 years (interquartile range, 44-65 years). Multivariate analysis showed that the risk factors associated with rotator cuff disease were Achilles
tendinitis (odds ratio [OR] = 1.78), trigger finger (OR = 1.99), lateral epicondylitis (OR = 1.71), and carpal tunnel syndrome (OR = 1.55). Oral corticosteroid therapy (OR = 2.03), oral antidiabetic use (OR = 1.66), insulin use (OR = 1.77), and \"overweight\" body mass index of 25.1 to 30 (OR = 1.15) were also significantly associated. Current or previous smoking history, body mass index of greater than 30, any alcohol intake, medial epicondylitis, de Quervain syndrome, cubital tunnel syndrome, and rheumatoid arthritis were not found to be associated with rotator cuff disease.
CONCLUSIONS: We have identified a number of comorbidities and risk factors for rotator cuff disease. These include lateral epicondylitis, carpal tunnel syndrome, trigger finger, Achilles
tendinitis, oral corticosteroid use, and diabetes mellitus. The findings should alert the clinician to comorbid pathologic processes and guide future research into the etiology of this condition.