surgical outcome

手术结果
  • 文章类型: Journal Article
    原发性脊髓肿瘤是罕见的肿瘤,通常是异质性的,具有可变的组织病理学亚型。迅速,椎管内不断增长的占位性病变会导致功能严重丧失。本研究旨在分析所有诊断为原发性脊髓肿瘤的成年患者,并描述其位置,症状,组织病理学类型,手术结果,并发症,在一个机构中复发,和预后因素。
    该研究是一项回顾性研究,对2014年至2021年在三级护理研究所神经外科接受手术干预的178例脊柱肿瘤患者进行了回顾性研究。患者人口学特征,症状,放射学特征,肿瘤的脊髓水平,脊柱室,术前和术后麦考密克等级,记录并发症,并对手术干预后的结局进行了比较.
    在我们的研究中,97例患者为男性,其余81例患者为女性。手术时的平均年龄为43.5岁。椎管的胸腔区域最累及67例(37.64%),而硬膜内髓外是最常见的(65.73%)。神经鞘瘤是最常见的组织病理学亚型(46.06%)。154例实现了全部切除。共有37例患者术前处于改良麦考密克等级的4级和5级。然而,术后,该组只有17名患者。两名颈髓内肿瘤患者在术后过期。
    具有良好的显微神经外科手术技巧的早期手术干预可获得良好的预后,而与肿瘤的类型和位置无关。在硬膜外肿瘤中可以看到更好的结果,早期手术干预,肿瘤更适合全切除,以及术前神经状况较好的患者。
    UNASSIGNED: Primary spinal cord tumors are rare tumors that are usually heterogeneous having variable histopathological subtypes. Rapidly, growing space-occupying lesions in the spinal canal cause severe loss of function. This study aimed to analyze all adult patients diagnosed with primary spinal cord tumors and to describe their location, symptoms, histopathological types, surgical outcome, complications, recurrence in a single institution, and prognostic factors.
    UNASSIGNED: The study was a retrospective study of 178 patients with spinal tumor who underwent surgical intervention at the department of neurosurgery at a tertiary care institute from 2014 to 2021. Patient demographic characteristics, symptoms, radiological features, spinal level of tumor, spinal compartment, preoperative and postoperative McCormick grade, and complications were recorded, and a comparison of outcomes after surgical intervention was done.
    UNASSIGNED: In our study, 97 patients were males and the rest of the 81 patients were females. The mean age at the time of surgery was 43.5 years. The thoracic region of the spinal canal was the most involved with 67 (37.64%) cases, whereas intradural extramedullary was the most common (65.73%). Schwannoma was the most common histopathological subtype (46.06%). Total excision was achieved in 154 cases. A total of 37 patients were in Grades 4 and 5 of modified McCormick\'s grade preoperatively. However, postoperatively, there were only 17 patients in this group. Two patients with cervical intramedullary tumor expired in the postoperative period.
    UNASSIGNED: Early surgical intervention with sound microneurosurgical skills gives good outcomes independent of the type and location of tumor. Better outcomes are seen in extradural tumors, early surgical intervention, tumors better amenable to total resection, and in patients with better preoperative neurological status.
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  • 文章类型: Case Reports
    我们报告了一例53岁的女性,该女性在进行无并发症的机器人子宫切除术和双侧附件卵巢切除术以治疗绝经后出血后立即出现气管支气管软化症。中度困难插管时,麻醉诱导明显,通过GlideScope施加环甲压力和小的6.5气管内导管放置来管理。手术过程顺利。患者仍在麻醉后护理单元中插管,但未提供潮气量。尝试用较大的导管替换气管导管失败,患者暂时无法通气。快速故障排除发现喉罩气道(LMA)可以为患者充分通气。一位耳鼻喉科医生能够进行直接支气管镜检查,显示气管和支气管的动态前后塌陷超过50%。病人随后被麻醉苏醒,并在重症监护室接受监测,用LMA通风。几个小时后,确定患者的气道受到保护,LMA被移除.
    We report the case of a 53-year-old female who developed tracheobronchomalacia immediately following an uncomplicated robotic hysterectomy with bilateral salpingo-oophorectomy to treat postmenopausal bleeding. Induction of anesthesia was notable for moderately difficult intubation, managed with applied cricothyroid pressure and a small 6.5 endotracheal tube placement via GlideScope. The surgical course was uneventful. The patient remained intubated in the post-anesthesia care unit but was not providing end-tidal volumes. Attempts to replace the endotracheal tube with a larger tube were unsuccessful and the patient was temporarily unable to ventilate. Rapid troubleshooting discovered that a laryngeal mask airway (LMA) could sufficiently ventilate the patient. An otolaryngologist was able to perform direct bronchoscopy, which revealed more than 50% dynamic anterior-posterior collapse of the trachea and bronchi. The patient was subsequently awakened from anesthesia and monitored in the intensive care unit, ventilating with an LMA. After a couple of hours, it was determined that the patient\'s airway was protected, and the LMA was removed.
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  • 文章类型: Multicenter Study
    UNASSIGNED:盘状内侧半月板是一种罕见的先天性膝关节异常。文献仅限于小型案例系列。
    UNASSIGNED:我们的目的是报告来自北美多个中心的儿童盘状内侧半月板的临床表现和手术治疗。我们假设症状和体征,关节镜检查结果,手术治疗,结果与有症状的盘状外侧半月板相似。
    未经批准:案例系列;证据级别,4.
    UNASSIGNED:一项回顾性研究确定了2000年1月至2021年6月间在8家儿童医院手术中确诊的盘状内侧半月板患者。对有关盘状外侧半月板的文献进行了回顾和总结,以进行比较。
    未经批准:共有21名患者(9名女性,确定了12名男性)和22个盘状内侧半月板。诊断时的平均±SD年龄为12.8±3.8岁。最常见的症状和体征是锁定和/或碰撞,出现在22个膝盖中的12个(55%),与盘状外侧半月板患者的报道相似。12个盘状内侧半月板完整(55%);8,不完整(36%);2,不确定(9%)。眼泪出现在13个膝盖上,最常见的水平卵裂(54%)。五个盘状内侧半月板不稳定(23%):3个为后部撕裂,2个为边缘功能不全。所有22个膝盖都接受了关节镜检查,在13个撕裂的半月板中,7(54%)被修复。中位随访时间为24个月(范围,2-82个月)。四个膝盖接受了再次手术。所有需要再次手术的膝盖都接受了后部撕裂的修复。手术修复与需要再次手术之间存在显着关联(P=.0048)。在盘状外侧半月板的病例系列患者中,周围不稳定的发生率也很高。
    UNASSIGNED:盘状内侧半月板患者的患者表现和治疗与盘状外侧半月板患者的报道相似。盘状内侧半月板的膝盖也表现出不稳定,归因于周围功能不全和后部撕裂。泪液出现在半数以上的膝盖盘状内侧半月板,再次手术在接受眼泪修复的膝盖中比没有修复的膝盖更常见。
    The discoid medial meniscus is a rare congenital anomaly of the knee. The literature is limited to small case series.
    Our purpose is to report the clinical manifestations and operative treatments of discoid medial menisci in children from multiple centers in North America. We hypothesized that symptoms and signs, arthroscopic findings, surgical treatments, and outcomes are similar to those for symptomatic discoid lateral menisci.
    Case series; Level of evidence, 4.
    A retrospective review identified patients with a diagnosed discoid medial meniscus confirmed at surgery across 8 children\'s hospitals between January 2000 and June 2021. The literature on discoid lateral menisci was reviewed and summarized for comparison.
    A total of 21 patients (9 female, 12 male) with 22 discoid medial menisci were identified. The mean ± SD age at the time of diagnosis was 12.8 ± 3.8 years. The most common symptoms and signs were locking and/or clunking, present in 12 of 22 knees (55%), similar to that reported in patients with discoid lateral menisci. Twelve discoid medial menisci were complete (55%); 8, incomplete (36%); and 2, indeterminate (9%). Tears were present in 13 knees, most commonly horizontal cleavage (54%). Five discoid medial menisci were unstable (23%): 3 for posterior tears and 2 for rim insufficiency. All 22 knees underwent arthroscopic saucerization, and of the 13 torn menisci, 7 (54%) were repaired. The median follow-up was 24 months (range, 2-82 months). Four knees underwent reoperation. All knees that required reoperation had undergone repair for a posteriorly located tear. There was a significant association between operative repair and need for reoperation (P = .0048). High rates of peripheral instability were also noted in case series of patients with discoid lateral menisci.
    Patient presentations and treatments for those with discoid medial menisci were similar to those reported for patients with discoid lateral menisci. Knees with discoid medial menisci also demonstrated instability attributed to peripheral insufficiency and posterior tears. Tears were present in over half of knees with discoid medial menisci, and reoperation was more common in knees that underwent repair of tears than those without repair.
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  • 文章类型: Journal Article
    目的:利用MRI报告的自然语言处理(NLP)和各种临床变量来开发预测下背部和颈部疼痛患者是否需要手术的初步模型。这样的模型将有利于为临床实践决策提供信息,并有助于减少不必要的手术转诊次数。简化手术过程.
    方法:使用转诊到脊柱评估诊所的患者的去识别数据进行了一项历史队列研究。各种人口统计,临床,和放射学变量作为潜在预测因子。在应用机器学习算法开发预测谁接受手术的模型之前,使用NLP对患者的MRI发现的全文放射学报告进行矢量化。然后将这些模型的输出输入到具有临床变量的逻辑回归模型中,以开发预测手术建议的初步模型。
    结果:在评估的398名患者中,71例接受了脊柱手术。NLP变量是单变量分析中的重要预测因子,但未保留在最终的逻辑回归模型中。接受手术的结果由下腰和腿部疼痛的主要症状预测(调整后的比值比2.81),疼痛图(调整后的比值比2.49)和自我报告的行走困难(调整后的比值比2.73)显示远端疼痛.
    结论:建立了一个逻辑回归模型来预测哪些患者可能需要脊柱手术。简单的临床变量似乎比使用NLP创建的变量更具预测性。然而,需要更多数据样本的额外研究来验证该模型,并全面评估NLP对这项任务的有用性.
    OBJECTIVE: To utilize natural language processing (NLP) of MRI reports and various clinical variables to develop a preliminary model predictive of the need for surgery in patients with low back and neck pain. Such a model would be beneficial for informing clinical practice decisions and help reduce the number of unnecessary surgical referrals, streamlining the surgical process.
    METHODS: A historical cohort study was conducted using de-identified data from patients referred to a spine assessment clinic. Various demographic, clinical, and radiological variables were included as potential predictors. Full-text radiology reports of patients\' MRI findings were vectorized using NLP before applying machine learning algorithms to develop models predicting who underwent surgery. Outputs from these models were then entered into a logistic regression model with clinical variables to develop a preliminary model predictive of surgical recommendations.
    RESULTS: Of the 398 patients assessed, 71 underwent spine surgery. NLP variables were significant predictors in univariate analysis but did not remain in the final logistic regression model. An outcome of receiving surgery was predicted by a primary symptom of low back and leg pain (adjusted odds ratio 2.81), distal pain indicated by a pain diagram (adjusted odds ratio 2.49) and self-reported difficulties walking (adjusted odds ratio 2.73).
    CONCLUSIONS: A logistic regression model was created to predict which patients may require spine surgery. Simple clinical variables appeared more predictive than variables created using NLP. However, additional research with more data samples is needed to validate this model and fully evaluate the usefulness of NLP for this task.
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  • 文章类型: Journal Article
    UNASSIGNED: Endovascular techniques are becoming more common for cerebral aneurysms, but not all patients are suitable and open surgery is necessary for some. The traditional pterional approach requires a large craniotomy and this carries some morbidity in itself. With the growing expectation for minimally invasive surgery, we present our experience in supraorbital mini-craniotomy for good grade aneurysmal subarachnoid haemorrhage.
    UNASSIGNED: Data on good-grade subarachnoid haemorrhage patients having aneurysms clipped via this approach were collected prospectively. Aneurysms at all anterior circulation sites were included, with the exception of the pericallosal artery, which was not within reach. A long-term follow-up questionnaire was sent to patients who had a supraorbital approach to clip the aneurysm at more than 1 year from hospital discharge.
    UNASSIGNED: Our results demonstrate mortality of 1% and severe residual disability in 10% of patients. Approach-related complications were low and it was considered that the operating space was not restricted in any of our cases. Return to work was achieved in 70% of patients who were working at the time of their haemorrhage.
    UNASSIGNED: Supraorbital micro-craniotomy is a safe approach for patients with proximal anterior circulation aneurysms, with low mortality and morbidity.
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  • 文章类型: Case Reports
    背景:中间神经痛(NIN),称为膝状神经痛(GN),是一种罕见的颅神经疾病,由压迫中间神经(NI)的血管引起。微血管减压术(MVD)可以解决NI根入区神经血管冲突(NVC),现已成为NIN的一种有价值的治疗方法。在不断优化和提高MVD手术技术的时代,进一步减少所有可能的术后并发症不仅是受欢迎的,而且是必要的。目的:这项工作的目的是评估MVD过程中直接可视化NI的术后结果。方法:本研究回顾了我们诊所2013-2020年期间接受MVD的7例NIN患者的临床记录,16项研究报告了2007-2020年期间接受MVD的NIN患者。结果:总的来说,所有患者中有91.3%的患者在MVD后颅神经痛得到了立即和完全缓解。23例患者中有6例在术中经历了NI的直接可视化,其中66.7%的患者有面瘫等并发症,失语症,或这些情况的组合术后。与手术入路相关的轻微并发症,例如与脑脊液(CSF)过度引流相关的投诉,恶心和眩晕,其余15例患者中有80%观察到伤口延迟愈合,这些症状在6个月后的电话和门诊随访中完全缓解。结论:我们的病例系列显示,MVD在大多数NIN患者中立即缓解疼痛。MVD有手术风险,尤其是在手术中机械拉伸和钝器解剖后经历NI直接可视化的患者。尝试避免机械拉伸和钝性解剖受压神经对术中神经保护很重要。尤其是面神经保护.
    Background: Nervus intermedius neuralgia (NIN), known as geniculate neuralgia (GN), is an uncommon cranial nerve disease caused by an offending vessel compressing the nervus intermedius (NI). Microvascular decompression (MVD) has now become a valued treatment approach for NIN because it can resolve neurovascular conflict (NVC) at the root entry zone of the NI. In the era of continuously optimizing and improving the surgical technique of MVD, further minimization of all possible postoperative complications is not only welcome but also necessary. Objective: The aim of this work is to assess the postoperative outcome of direct visualization of the NI during the MVD procedure. Methods: This study retrospectively reviewed the clinical records of a group of seven consecutive patients with NIN who underwent MVD in the period of 2013-2020 in our clinic and 16 studies reported NIN patients who underwent MVD in the period of 2007-2020. Results: In total, 91.3% of all patients experienced immediate and complete relief of cranial neuralgia after MVD. Six of 23 patients have experienced direct visualization of the NI intraoperatively, and 66.7% of those patients had complications such as facial paralysis, dysacousia, or a combination of these conditions postoperatively. Slight surgical approach-related complications such as complaints associated with excessive drainage of cerebrospinal fluid (CSF), nausea and vertigo, and delayed wound union were observed in 80% of the remaining 15 patients, and these symptoms are totally relieved in the telephone and outpatient follow-up after 6 months. Conclusion: Our case series shows that MVD produced immediate pain relief in the majority of NIN patients. MVD carries surgical risk, especially in patients who experience direct visualization of the NI after mechanical stretch and blunt dissection in surgical procedures. Attempts to avoid mechanical stretch and blunt dissection of the compressed nerve were important for intraoperative neuroprotection, especially facial nerve protection.
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  • 文章类型: Journal Article
    Anterior cervical corpectomy and fusion (ACCF) is a treatment option for several cervical pathologies. Various graft materials such as autografts, titanium mesh cages (TMC), or poly-ether-ether-ketone (PEEK) cages are used. Additional posterior fixation (PF) to provide extra support and improve stability is sometimes performed initially, or later as supplementary treatment.
    To describe our retrospective study of 119 consecutive cases of ACCF with synthetic grafts, in 3 cohorts of cervical spondylotic myelopathy (CSM), infectious and neoplastic processes, and trauma, with special focus on need for supplementary PF.
    A total of 135 adult patients treated with ACCF between January 2005 and January 2018 were identified. Patients lost to follow-up were excluded, and 119 remaining patients were included for retrospective clinical and radiological assessment.
    Synthetic grafts were used in 116 (97%) cases. Only 9 (8%) ACCF cases required later supplementary PF, where 7 (78%) cases were multilevel. There was a statistically significant difference in revision rate with PF for single-level compared to multilevel ACCFs (P = .001). Revision rates with PF were 2%, 29%, and 7% in CSM, infectious and neoplastic processes, and trauma cohorts, respectively.
    The results indicate that ACCF is a safe and effective treatment for degenerative and traumatic cervical spine disorders, with low complication and revision rates. Single-level ACCF can be performed without additional PF. Multilevel ACCF (n > 2) and pathologies affecting bone quality seem to be risk factors for material subsidence and instability. In these cases, additional PF should be considered.
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  • 文章类型: Journal Article
    Quantitative documentation of the effects of outbreaks, including the coronavirus disease 2019 (COVID-19) pandemic, is limited in neurosurgery. Our study aimed to evaluate the effects of the COVID-19 pandemic on neurosurgical practice and to determine whether surgical procedures are associated with increased morbidity and mortality.
    A multicenter case-control study was conducted, involving patients who underwent neurosurgical intervention in the Kingdom of Saudi Arabia during 2 periods: pre-COVID-19 and during the COVID-19 pandemic. The surgical intervention data evaluated included diagnostic category, case priority, complications, length of hospital stay, and 30-day mortality.
    A total of 850 procedures were included, 36% during COVID-19. The median number of procedures per day was significantly lower during the COVID-19 period (5.5 cases) than during the pre-COVID-19 period (12 cases; P < 0.0001). Complications, length of hospital stay, and 30-day mortality did not differ during the pandemic. In a multivariate analysis comparing both periods, case priority levels 1 (immediate) (odds ratio [OR], 1.82; 95% confidence interval [CI], 1.24-2.67), 1 (1-24 h) (OR, 1.63; 95% CI, 1.10-2.41), and 4 (OR, 0.28; 95% CI, 0.19-0.42) showed significant differences.
    During the early phase of the COVID-19 pandemic, the overall number of neurosurgical procedures declined, but the load of emergency procedures remained the same, thus highlighting the need to allocate sufficient resources for emergencies. More importantly, performing neurosurgical procedures during the pandemic in regions with limited effects of the outbreak on the health care system was safe. Our findings may aid in developing guidelines for acute and long-term care during pandemics in surgical subspecialties.
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  • 文章类型: Case Reports
    立体脑电图(SEEG)引导的射频热凝(RF-TC)的最佳结果在病变较有限的癫痫中观察到,但是这种方法很少用于广泛的大脑畸形。我们报告了一例罕见的多微病毒(PMG)合并抗药性惊厥发作的病例。由于PMG的大病变和复杂性,使用SEEG进行了术前监测。根据颅内电极结果,癫痫发作广泛,与其他电极的其他部位相比,在扣带沟和岛状极开始的时间更早。多点和多步骤SEEG引导的RF-TC用于弥漫性病变和功能保护。RF-TC首先应用于扣带沟和岛状极,我们的患者在2周后免于惊吓性癫痫发作。两周的观察有助于我们观察RF-TC的疗效和SEEG的变化,从而制定下一个TC方案。患者在第一次治疗后仍有自发性癫痫发作。然后将RF-TC应用于较早涉及的其他站点。最后,患者达到EngelIIa级,随访1年.没有额外的惊吓发作,重要功能区得到保护。
    The best results of stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation (RF-TC) were observed in epilepsies with more limited lesions, but this procedure is rarely used in a wide range of brain malformation. We report a rare case of polymicrogyria (PMG) combined with drug-resistant startle seizures. Presurgical monitoring was performed using SEEG owing to the large lesion and complexity of PMG. According to the intracranial electrode results, the seizure onset was extensive, with the onset starting earlier in the cingulate sulcus and insular pole than in other sites of the other electrodes. Multi-point and multi-step SEEG-guided RF-TC was used for diffuse lesion and functional protection. RF-TC was first applied to the cingulate sulcus and insular pole, and our patient was rendered free from startle seizures after 2 weeks. Two weeks of observation helped us to observe the efficacy of RF-TC and the changes of SEEG, so as to make the next TC scheme. The patient still had spontaneous seizures after the first treatment. RF-TC was then applied to other sites involved earlier. Finally, the patient reached Engel class IIa for a follow-up period of 1 year. There were no additional startle seizures, and important functional areas were protected.
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  • 文章类型: Journal Article
    BACKGROUND: Primary carcinosarcoma is a rare neoplasm of the gallbladder, and is characterized by collision elements of the adenocarcinomatous and sarcomatous components. The tumours comprise both malignant epithelial and mesenchymal elements, and are usually very aggressive, conferring poor prognosis. Adenocarcinomas are the most common neoplasms of the gall bladder, while carcinosarcoma are extremely rare, with a global prevalence rate of less than 1%. The low incidence of carcinosarcoma greatly hinders the understanding of its aetiology.
    METHODS: Here, we report the surgical outcome of 3 rare cases of gallbladder carcinosarcomas, two of which had a IVB stage disease and in one case the staging was II. Following surgery, the survival in the former was less than 1 year, while in the latter, it extended up to 7 years (86 months), and the patient is alive till date. This study aimed to elucidate the surgical outcomes and prognosis after curable resection for carcinosarcomas of the gallbladder.
    CONCLUSIONS: The findings suggest that carcinosarcomas are associated with a poor prognosis and short survival, particularly in those with tumours of >5 cm. In the absence of effective adjuvant treatment, surgery remains the mainstay of treatment.
    CONCLUSIONS: Complete surgical resection may improve prognosis and extend survival in patients with this rare and aggressive form of gallbladder cancer.
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