上半规管裂开(SSCD)是最近定义的发育缺陷,可能与几种颅面异常有关,例如唇裂/腭裂(CLP)。本研究旨在比较受试者与单侧和双侧CLP和正常对照的上半规管(SSC)骨厚度和模式。
共收集了52例单侧唇腭裂(UCLP)受试者(104例颞骨)和38例双侧唇腭裂(BCLP)受试者(76例颞骨)和148例健康对照(296例颞骨)的238例锥束计算机断层扫描(CBCT)图像。SSC骨厚度测量两次,并由颌面放射科医生进行验证。然后根据骨厚度将样品分为五类:纸莎草纸或薄,正常,厚,气动,和裂开。毕竟,UCLP,BCLP,与正常对照组比较SSC模式和厚度。
结果显示,根据性别,在SSC模式和厚度方面,三组之间没有显着差异。SSC模式(P值=.001)和SSC厚度(0.01)与裂隙类型密切相关。在BCLP患者中,骨厚度最薄,SSCD发生率最高。
结果显示SSC模式和SSC厚度与研究组之间存在显著关联。
Superior Semicircular Canal Dehiscence (SSCD) is a recently-defined developmental defect may be associated with several craniofacial anomalies such as Cleft Lip/Palate (CLP). The present
study aimed to compare subjects with unilateral and bilateral CLP and normal controls in terms of Superior Semicircular Canal (SSC) bone thickness and pattern.
A total of 238 Cone Beam Computed Tomography (CBCT) images were collected from 52 unilateral Cleft Lip and Palate (UCLP) subjects (104 temporal bones) and 38 Bilateral Cleft Lip and Palate (BCLP) (76 temporal bones) subjects and 148 healthy controls (296 temporal bones). The SSC bone thickness was measured twice and validated by a maxillofacial radiologist. The samples were then classified into five categories based on bone thickness: papyraceous or thin, normal, thick, pneumatized, and dehiscence. After all, the UCLP, BCLP, and normal control groups were compared concerning the SSC pattern and thickness.
The results revealed no significant difference among the three groups regarding the SSC pattern and thickness based on gender. The SSC patterns (P value = .001) and SSC thickness (0.01) were strongly correlated to the cleft type. The thinnest bone thickness and the highest incidence of SSCD were observed among the subjects with BCLP.
The results showed a significant association between the SSC patterns and SSC thickness and the
study groups.