UNASSIGNED: Squamous cell papilloma is a benign tumor whose pathogenesis is generally related to the human papillomavirus. Despite affecting several organs, we did not find cases reported in the nails.
UNASSIGNED: A 67-year-old female presented with a painful lesion in the nail of the right hallux that started in 2021, with an erythematous appearance evolving to black and expansive growth. Due to the evolution and symptoms, she opted for excision, with a histopathological report of squamous cell papilloma. Complementary treatment with imiquimod was performed, with good healing and pain control.
UNASSIGNED: Due to the lack of previous reports, treatment was based on therapeutic options for papillomas located in other regions. Excision was performed, followed by application of imiquimod with good response. The prognosis is favorable; however, further studies are needed to elucidate the diagnosis and management of nail squamous cell papilloma.

Simultaneous multiple primary tumors on the same side of the lung with Tropheryma whipplei (TW) infection are rare. We reviewed the clinical data, imaging manifestations, pathological results, diagnosis and treatment of a primary pulmonary mucinous adenocarcinoma (PPMA) patient with bronchial squamous cell papilloma (BSCP) and TW infection, and discussed our treatment experience. The patient mainly presented with chronic cough and sputum, and computed tomography (CT) showed inflammatory changes with multiple nodular shadows. Biopsy of the lower lobe of the right lung showed PPMA, and right lung sub-branchial nodules discovered during bronchoscope revealed BSCP. Metagenomics next generation sequencing (mNGS) of bronchoalveolar lavage fluid showed mixed infection of Streptococcus pneumoniae and TW with a poor anti-infective effect. No clear genetic mutation was detected, and the patient was treated with chemotherapy and regularly followed up. We should improve the awareness of multiple pulmonary pathologies during clinical practice, avoid missed diagnosis and misdiagnosis, and carry out comprehensive treatment after clarifying the diagnosis as soon as possible.
.
【中文题目：肺黏液腺癌合并鳞状细胞乳头状瘤
及惠普尔养障体感染1例】 【中文摘要：肺部同侧同时双原发性肿瘤且合并惠普尔养障体（Tropheryma whipplei, TW）感染较为少见，本文对1例原发性肺黏液腺癌（primary pulmonary mucinous adenocarcinoma, PPMA）合并支气管鳞状细胞乳头状瘤（bronchial squamous cell papilloma, BSCP）及TW感染患者的临床资料、影像学表现、病理结果及诊疗经过进行回顾，并分析诊疗经验。患者主要表现为长期咳嗽咳痰，胸部计算机断层扫描（computed tomography, CT）示双肺炎症改变与多发结节影，右肺下叶穿刺活检结果为PPMA；常规气管镜见右肺亚支结节，活检结果为BSCP。肺泡灌洗液高通量测序（metagenomics next generation sequencing, mNGS）结果考虑肺炎链球菌、TW混合感染，抗感染效果不佳。胸水未检测到明确基因突变，行化疗并定期随访。在临床中应该提高对肺部多发病变的认识，避免漏诊、误诊，尽快明确诊断后进行综合治疗。
】 【中文关键词：肺肿瘤；肺黏液腺癌；鳞状细胞乳头状瘤；惠普尔养障体】.

Bladder noninvasive squamous lesions are usually rare; here, we are presenting a case of 39 years old male patient with a benign squamous cell papilloma. The tumor grossly presented as cauliflower mass mimicking squamous cell carcinoma, while histologically, the tumor showed extensive keratinization at its surface and showed no nuclear atypia or stromal invasion. This tumor is benign and extremely rare. In this manuscript, we summarized a case of Squamous cell papilloma of the bladder with the first operative video for the transurethral resection of squamous cell papilloma with percutaneous management of associated urinary bladder stones.

Squamous cell papilloma of the gingiva is a benign, asymptomatic, exophytic nonplaque-associated gingival lesion caused by human papillomavirus. It affects several areas of the oral cavity with a relatively lower predilection for gingiva. The finger-like clinical presentation may be scary, misleading and may be confused with other lesions. This report presents a case of squamous cell papilloma of the gingiva. We report an unusual case of squamous papilloma of the gingiva with an unusual \"garlanding a tooth\" appearance.

Lymphoid papillary hyperplasia of the tonsils is a rare, benign lesion and is characterized by a papillomatous appearance with reactive follicular hyperplasia. Our case was unique because the lesion involved the unilateral and focal palatine tonsil, as the lesion usually involves the bilateral and entire palatine tonsils.