超过一半的中风患者经历感觉功能障碍,影响他们的生活质量。以前的训练方式在改善感觉功能方面无效。相比之下,无创性脑刺激(NIBS)是一种新的有前途的脑卒中康复干预措施。这项荟萃分析的目的是总结NIBS治疗中风后感觉功能障碍的当前有效性。文章发表在PubMed,WebofScience,Embase,中国国家知识基础设施(CNKI),中国科技期刊全文数据库(VIP),和万方数据库从成立到2023年3月8日进行了检索。语言没有限制。总共包括14个RCT(组合n=804)。中等质量的证据表明,NIBS显著改善卒中后的感觉功能,并在干预后1年内观察到显著的效果。在亚组分析中,经颅直流电刺激(tDCS)或重复经颅磁刺激(rTMS)治疗对脑卒中患者感觉功能的恢复明显比对照组更有效.刺激初级运动皮层(M1),初级体感皮层(S1)或M1+S1刺激部位显著改善感觉功能。在不同阶段的中风患者中,NIBS对感觉功能障碍具有显着的治疗潜力。在NIBS刺激少于10次的受试者中没有观察到显著的效果。用高频或低频rTMS观察到显著的治疗效果。
More than half of stroke patients experience
sensory dysfunction that affects their quality of life. Previous training modalities are ineffective in improving
sensory function. In contrast, non-invasive brain stimulation (NIBS) is a new promising intervention for stroke rehabilitation. The aim of this meta-analysis was to summarize the current effectiveness of NIBS in the treatment of post-stroke
sensory dysfunction. Articles published in PubMed, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), Chinese scientific journals full-text database (VIP), and Wanfang database from the inception to March 8, 2023 were searched. There were no restrictions on language. A total of 14 RCTs were included (combined n = 804). Moderate-quality evidence suggested that NIBS significantly improved
sensory function after stroke, and significant effects were observed up to 1 year after the intervention. In subgroup analysis, treatment with transcranial direct current stimulation (tDCS) or repetitive transcranial magnetic stimulation (rTMS) was significantly more effective than controls for recovery of sensory function in stroke patients. Stimulation of the primary motor cortex (M1), primary somatosensory cortex (S1) or M1 + S1 stimulation sites significantly improved sensory function. NIBS for
sensory dysfunction showed significant therapeutic potential in patients with different stages of stroke. No significant effects were observed in subjects with less than 10 NIBS stimulations. Significant therapeutic effects were observed with either high-frequency or low-frequency rTMS.