皮脂腺癌是一种罕见的,侵袭性皮肤恶性肿瘤最常见于眼周区域。皮脂腺癌的眼外位置,特别是在头部和颈部区域之外,是罕见的,没有很好的描述。我们报告了一例89岁的白人女性,患有右手腕皮脂腺癌。她最初在右手腕上出现了一个1.2厘米的易碎结节。最初的剃须活检和随后的病理评估显示有皮脂腺分化的基底细胞样肿瘤,非典型,和频繁的有丝分裂,符合皮脂腺癌.该病例回顾了眼部和眼外皮脂腺癌的常见临床特征和相关组织病理学,并提供了诊断的文献综述。预后,和治疗。
Sebaceous carcinoma is a rare, aggressive cutaneous malignancy most commonly arising from the periocular area. Extraocular locations of sebaceous carcinomas, particularly outside of the head and neck region, are rare and not well-described. We report a
case of an 89-year-old Caucasian female with sebaceous carcinoma of the right wrist. She initially presented with a 1.2-centimeter friable nodule on the right wrist. Initial shave biopsy and subsequent pathologic evaluation revealed a basaloid neoplasm with sebaceous differentiation, atypia, and frequent mitoses, consistent with sebaceous carcinoma. The presented
case reviews common clinical features and the pertinent histopathology of ocular and extraocular sebaceous carcinoma and provides a literature review of diagnosis, prognosis, and treatment.