背景:文献中的新兴研究继续预测,人群中的负面心理健康和睡眠健康结果将急剧增加,特别是在COVID-19大流行之后,这极大地影响了人们的生活方式。随着精神卫生药物干预措施继续受到污名化,在人群中无法获得,天然补充剂为干预提供了机会。
目的:本研究旨在对有关营养补充剂对焦虑症状具有最大治疗作用的最新综合证据的文献进行系统回顾。抑郁症,和失眠。
方法:系统的文献搜索,利用几个数据库,包括PubMed和WebofScience,于2022年4月29日进行。我们使用开发的关键字和MeSH术语进行搜索。研究资格标准包括(1)随机对照试验;(2)调查基于植物的治疗或天然补充剂作为干预措施;(3)测量以下至少一种健康结果:焦虑症状,抑郁症状,或睡眠健康结果;(4)利用经过验证的测量工具来测量感兴趣的结果;(5)用英语书写;(6)同行评审;(7)专注于成年人和老年人群。
结果:遵循PRISMA指南,本综述包括76项研究。我们使用修订的风险偏倚工具(RoB2)来评估所有纳入的随机对照试验的质量。进行了定性数据合成。总的来说,我们从文献中的证据中发现了一些有价值的见解,包括证明益生菌和维生素B复合物对焦虑症状有益的证据,抑郁症状,和睡眠质量。关键发现的含义:这篇综述提供了有关该主题的文献中最新的发现,包括过去5年发表的大量研究。考虑到大流行后负面精神和睡眠健康结果的预期上升,本研究中确定的补充剂和治疗应成为干预措施的目标,以增加其可及性和可负担性,并将其纳入临床治疗指南.PROSPERO注册号:CRD42022361130。
The emerging research in the literature continues to forecast a drastic and alarming increase in negative mental health and sleep health outcomes among populations, especially after the COVID-19 pandemic, which significantly influenced people\'s way of life. With mental health pharmaceutical interventions continuing to be stigmatized and inaccessible among populations, natural supplements provide an opportunity for intervention.
This study sought to conduct a systematic
review of the literature on the most recent comprehensive evidence for which nutritional supplements have the greatest therapeutic impact on symptoms of anxiety, depression, and insomnia.
A systematic search of the literature, utilizing several databases, including PubMed and Web of Science, was conducted on 29 April 2022. We used developed keywords and MeSH terms for the search. The study eligibility criteria included (1) a randomized control trial; (2) investigating a plant-based therapeutic or natural supplement as the intervention; (3) measuring at least one health outcome of the following: anxiety symptoms, depressive symptoms, or sleep health outcomes; (4) utilizing validated measurement tools to measure the outcome of interest; (5) written in the English language; (6) peer reviewed; and (7) focused on adults and elderly populations.
Following the PRISMA guidelines, 76 studies were included in this
review. We used the revised Risk of Bias tool (RoB2) to assess the quality of all included randomized control trials. A qualitative data synthesis was conducted. Overall, we found several valuable insights from the evidence in the literature, including evidence that demonstrates the benefits of probiotics and vitamin B complexes on anxiety symptoms, depressive symptoms, and sleep quality. Implication of Key Findings: This
review provides the most updated findings in the literature on the topic, including an abundance of research that was published in the past 5 years. Given the expected rise in negative mental and sleep health outcomes following the pandemic, the supplements and therapeutics identified in this study should be the target of intervention measures to increase their accessibility and affordability and allow them to be incorporated into clinical guidelines of treatment. PROSPERO registration number: CRD42022361130.