UASSIGNED:社会反应量表(SRS)是一个65项指标,可连续得分,捕获自闭症相关特征。已对基于SRS项目子集的分数进行了分析检查,但尚未对缩短版本的管理进行前瞻性评估。
UNASSIGNED:这项研究的目的是将两种缩短版本的SRS的心理测量特性与完整的65项SRS进行比较,在临床和一般人群环境中的幼儿中。
UNASSIGNED:研究参与者(3-5岁)来自AJDrexel自闭症研究所诊所(n=154)和北加利福尼亚KaiserPermanente(n=201),并随机分组接受16项简短SRS,一种新开发的计算机自适应测试-SRS,或发布的全长SRS。对三种SRS给药方法的总分进行缩放以促进比较。绘制分数以评估分布特性,而接收器工作特性分析用于估计曲线下面积(AUC)和地址预测能力。
未经评估:总的来说,三种给药方法的分布特性具有高度可比性,缩短的措施表明,捕获分布范围和病例非病例分离的能力与完整SRS相似。此外,AUC值很高(0.91-0.97),并且在各种给药方法中具有可比性,尽管有证据表明女性的预测能力存在差异(完整SRS的AUC=0.99vs.简称0.84)。在短期和完整分数的个人比较中(仅适用于一般人群站点的参与者),建议低估CAT-SRS的实际完整SRS分数。
UNASSIGNED:我们的发现广泛支持本文研究的缩短SRS版本的结构有效性和性能,尽管可能需要全面的测量来更准确地评估与女性ASD诊断一致的特征。这项工作提出了在参与者负担或可行性考虑可能禁止此类测量的情况下收集ASD相关表型的机会。
UNASSIGNED: The Social Responsiveness Scale (SRS) is a 65-item measure yielding a continuous score capturing autism-related traits. Scores based on SRS item subsets have been analytically examined but administration of shortened versions has not been evaluated prospectively.
UNASSIGNED: The goal of this
study was to compare psychometric properties of two shortened versions of the SRS to the full 65-item SRS, in young children from both a clinical and general population setting.
UNASSIGNED: Study participants (aged 3-5 years) were drawn from the AJ Drexel Autism Institute clinic (n = 154) and Kaiser Permanente Northern California (n = 201) and block randomized to receive either the 16-item short SRS, a newly developed computer adaptive testing-SRS, or the published full-length SRS. Total scores across the three SRS administration methods were scaled to facilitate comparisons. Scores were plotted to assess distributional properties, while Receiver Operating Characteristic analysis was used to estimate Area Under the Curve (AUC) and address predictive ability.
UNASSIGNED: Overall, distributional properties of the three administration methods were highly comparable, with shortened measures demonstrating similar ability to capture the range of the distribution and case non-case separation as the full SRS. In addition, AUC values were high (0.91-0.97) and comparable across the administration methods, though there was evidence of difference in predictive ability across measures for females (AUC for full SRS = 0.99 vs. 0.84 for short). Within individual comparisons of short versus full scores (available only for participants at the general population site) suggested underestimation of actual full SRS scores with the CAT-SRS.
UNASSIGNED: Our findings broadly support the construct validity and performance of shortened SRS versions examined here, though the full measure may be needed to more accurately assess traits consistent with ASD diagnosis in females. This work suggests opportunities for collection of ASD-related phenotype in settings where participant burden or feasibility considerations may have otherwise prohibited such measurement.