目的:妊娠和产褥期被认为是系统性红斑狼疮(SLE)和抗磷脂综合征(APS)女性的危险因素。因此,在孕前和怀孕期间以及产褥期,专门的评估是必不可少的。同样,自身免疫性疾病和高危妊娠的不同专家以协调的方式参与这些患者的随访非常重要。西班牙妇产科学会,西班牙内科学会,西班牙风湿病学会成立了一个工作组,准备三份共识文件。
方法:工作的阶段是:与怀孕相关的三个时期相对应的三组中的工作分配(孕前,在怀孕和分娩和产褥期),确定关键领域,详尽的文献回顾和建议的制定。
结果:第一份文件包括48项涉及不孕症的建议,性腺保存和孕前评估的需要和治疗。
结论:这些多学科建议被认为是临床医生参与妊娠期SLE/APS患者护理的决策工具。
OBJECTIVE: Pregnancy and
puerperium are considered a risk situation in women with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). Therefore, specialized assessment is essential both preconception and during pregnancy and the
puerperium. Likewise, it is very important that different specialists in autoimmune diseases and high-risk pregnancies participate in the follow-up of these patients in a coordinated manner. The Spanish Society of Gynaecology and Obstetrics, the Spanish Society of Internal Medicine, and the Spanish Society of Rheumatology have set up a working group for the preparation of three
consensus documents.
METHODS: The stages of the work were: distribution of work in three groups corresponding to the three periods related to pregnancy (preconception, during pregnancy and childbirth and
puerperium), identification of key areas, exhaustive review of the literature and formulation of recommendations.
RESULTS: This first document includes the 48 recommendations that address aspects related to infertility, the need for and treatments for gonadal preservation and preconception assessment.
CONCLUSIONS: These multidisciplinary recommendations are considered decision-making tools for clinicians involved in the care of patients with SLE/APS during pregnancy.