未经证实:贫血是怀孕期间全球常见的疾病,给母亲带来一些健康风险。然而,对于贫血的严重程度和严重的产妇结局之间的关联知之甚少.这项研究旨在评估妊娠期贫血的严重程度与严重孕产妇结局风险之间的关系。
UNASSIGNED:这项回顾性队列研究基于2017-2018年中国全国孕产妇近错过监测系统的数据,该系统包括中国南方的18家医院。入院分娩的孕妇根据妊娠期贫血的严重程度分为4组:无贫血,轻度贫血,中度贫血,和严重贫血组。严重的产妇结局是威胁生命的疾病的复合(即,器官功能障碍)由WHO标准定义,发生在入院后的任何时间,直到出院或死亡。使用改良的Poisson回归分析和倾向评分加权回归分析来估计妊娠期不同严重程度贫血妇女的严重孕产妇结局的相对风险(RR)和95%置信区间(CI)。
UNASSIGNED:严重产妇结局的发生率为0.3%(417/138,556),率为0.1%(85/99,755),0.2%(30/18,502),1.2%(234/19,697)和11.3%(68/602)无贫血,轻度贫血,中度贫血和重度贫血组,分别。与无贫血相比,中度贫血组的重度产妇结局校正RR为4.19(95%CI,3.20~5.50),重度贫血组为22.12(95%CI,15.43~31.69);中度贫血组的加权RR为1.01(95%CI,1.01~1.01),重度贫血组为1.11(95%CI,1.07~1.14).
UNASSIGNED:妊娠期中度至重度贫血与严重产妇结局风险增加独立相关。孕产妇保健提供者和孕妇本身应更加重视妊娠期贫血的预防和治疗,尤其是中度至重度贫血。
UNASSIGNED: Anemia is a worldwide common condition during pregnancy, conferring a number of health risks to mothers. However, very little is known about the association between severity of anemia and severe maternal outcomes. This
study aimed to assess the association between severity of anemia during pregnancy and the risk of severe maternal outcomes.
UNASSIGNED: This retrospective cohort
study was based on data from China\'s National Maternal Near Miss Surveillance System for the period 2017-2018, which included 18 hospitals in southern China. Pregnant women admitted for delivery were divided into 4 groups based on severity of anemia during pregnancy: no anemia, mild anemia, moderate anemia, and severe anemia groups. Severe maternal outcomes were a composite of life-threatening conditions (ie, organ dysfunction) as defined by the WHO criteria, occurring at any time after admission until discharge or death. Modified Poisson regression analyses and propensity score-weighted regression analyses were used to estimate the relative risks (RRs) and 95% confidence intervals (CIs) of severe maternal outcomes among women with anemia of varying severity during pregnancy.
UNASSIGNED: The incidence of severe maternal outcomes was 0.3% (417/138,556) in total, and the rates were 0.1% (85/99,755), 0.2% (30/18,502), 1.2% (234/19,697) and 11.3% (68/602) in no anemia, mild anemia, moderate anemia and severe anemia group, respectively. Compared with no anemia, the adjusted RR for severe maternal outcomes was 4.19 (95% CI, 3.20-5.50) in moderate anemia group and 22.12 (95% CI, 15.43-31.69) in severe anemia group; the weighted RR was 1.01 (95% CI, 1.01-1.01) in moderate anemia group and 1.11 (95% CI, 1.07-1.14) in severe anemia group.
UNASSIGNED: Moderate to severe anemia during pregnancy was independently associated with an increased risk of severe maternal outcomes. Maternal health care providers and pregnant women themselves should give more attention to the prevention and treatment of anemia during pregnancy, especially moderate to severe anemia.