未经批准:冠状病毒-19病(COVID-19)已被世界卫生组织(WHO)于2020年3月宣布为大流行。截至2021年11月28日,COVID-19造成的病例超过2.6亿例,死亡近520万人。受COVID-19感染影响最大的系统是呼吸系统,尽管其他几项研究表明多器官参与病理生理学,但尚不清楚。尸检结果有利于研究人员确定这些器官衰竭背后的机制。本综述的目的是总结与COVID-19死亡相关的尸检结果。
UNASSIGNED:通过在线数据库进行在线文献检索,例如Scopus,PubMed和谷歌学者。搜索过程中输入的关键词是“验尸”,标题中的“尸检”和“COVID-19”,抽象和关键字。纳入标准是与本综述标题相关的主题,于2020-2021年出版,全文可用,英文。任何不相关的文章,重复的研究,包括系统综述和荟萃分析以及其他语言的综述文章被排除.
UNASSIGNED:本综述共包括20篇文章。审查的文章主要是病例报告和病例系列,而其他文章则是病例对照和队列研究,范围从1到348例。大多数起源于美利坚合众国(美国)。
未经证实:在COVID-19死亡的尸检结果中描述的最常见的系统是呼吸系统,最常见的组织学发现是弥漫性肺泡损伤(DAD)。其他器官的大部分发现与慢性病有关。
UNASSIGNED: Coronavirus-19 disease (COVID-19) has been declared as pandemic by the World Health Organization (WHO) in March 2020. As of 28 November 2021, there were more than 260 million cases and nearly 5.2 million deaths caused by COVID-19. The most affected system by COVID-19 infection was the respiratory system although several other studies suggested multi-organ involvement with pathophysiology that was not clearly understood. Autopsy findings were beneficial to researchers to determine the mechanism behind these organ failures. The objective of this
review was to summarize the autopsy findings related to COVID-19 death.
UNASSIGNED: Online literature search was conducted via online databases such as Scopus, PubMed and Google Scholar. The keywords inputted during the search were \"post-mortem\", \"autopsy\" and \"COVID-19\" in title, abstract and keywords. The inclusion criteria were the topic related with the title of this
review, published in 2020-2021, have full text available and in English language. Any articles that were not related, duplicated studies,
review articles including systematic
review and meta-analysis and in other languages were excluded.
UNASSIGNED: A total of 20 articles were included in this
review. The articles reviewed were mostly case reports and case series while others were case-control and cohort study ranging from one to 348 cases. Majority were originated from the United States of America (USA).
UNASSIGNED: The most frequent system described in autopsy findings in COVID-19 death was the respiratory system, with the most common histological finding of diffuse alveolar damage (DAD). Majority of the findings of other organs were related to chronic diseases.