干细胞研究进展的无意结果,神经科学,复苏科学已经使科学的见解,人类的大脑发生了什么与死亡有关。对死亡的科学探索在很大程度上是可能的,因为人们认识到脑细胞比想象的更能适应缺氧的影响。因此,脑细胞在死后数小时到数天内不可逆转地受损并“死亡”。复苏科学使数百万人的心脏停止后,生命得以恢复。这些幸存者描述了一系列与死亡有关的独特回忆,这些回忆似乎是普遍的。我们回顾了文献,专注于死亡,回顾与心脏骤停有关的经历,重症监护后综合征,以及提供对潜在机制的见解的相关现象,伦理含义,和系统调查的方法学考虑。我们还确定了与意识研究相关的问题和争议,以及昏迷受试者的心脏骤停和死亡的回忆经历,以规范和促进未来的研究。
An inadvertent consequence of advances in stem cell research, neuroscience, and resuscitation science has been to enable scientific insights regarding what happens to the human brain in relation to death. The scientific exploration of death is in large part possible due to the recognition that brain cells are more resilient to the effects of anoxia than assumed. Hence, brain cells become irreversibly damaged and \"die\" over hours to days postmortem. Resuscitation science has enabled life to be restored to millions of people after their hearts had stopped. These survivors have described a unique set of recollections in relation to death that appear universal. We review the literature, with a focus on death, the recalled experiences in relation to cardiac arrest, post-intensive care syndrome, and related phenomena that provide insights into potential mechanisms, ethical implications, and methodologic considerations for systematic investigation. We also identify issues and controversies related to the study of consciousness and the recalled experience of cardiac arrest and death in subjects who have been in a coma, with a view to standardize and facilitate future research.