背景:视神经脊髓炎谱系障碍(NMOSD)涉及中枢神经系统的自身免疫和炎症反应,主要影响视神经和脊髓。共济失调和晕厥等非典型表现使诊断复杂化,髓质病变很容易被误认为是脑梗塞。此病例报告强调必须认识到此类表现,以避免误诊并确保及时治疗。
方法:本病例报告介绍了一名经历共济失调的NMOSD女性患者,晕厥,和她生病期间的神经性疼痛。
方法:NMOSD。
方法:患者用胰岛素控制血糖,普瑞巴林控制的神经性疼痛,进行了5次血浆置换。
结果:血浆置换后1周显著改善,在6个月的随访中,神经性疼痛完全缓解,并且没有症状复发。
结论:NMOSD的非典型表现,比如共济失调,晕厥,三叉神经痛,增加诊断难度。认识到这些症状对于避免误诊并确保对患者进行及时和适当的治疗至关重要。
BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) involves autoimmune and inflammatory responses in the central nervous system, primarily affecting the optic nerves and spinal cord. Atypical presentations such as ataxia and syncope complicate the diagnosis, and lesions in the medulla are easily mistaken for cerebral infarction. This
case report emphasizes the need to recognize such manifestations to avoid misdiagnosis and ensure timely treatment.
METHODS: This
case report presents an NMOSD female patient who experienced ataxia, syncope, and neuropathic pain during her illness.
METHODS: NMOSD.
METHODS: The patient managed her blood sugar with insulin, controlled neuropathic pain with pregabalin, and underwent 5 plasma exchanges.
RESULTS: Significant improvement was noted 1 week post-plasma exchange, with complete resolution of neuropathic pain and no symptom recurrence reported at 6-month follow-up.
CONCLUSIONS: Atypical manifestations of NMOSD, such as ataxia, syncope, and trigeminal neuralgia, increase diagnostic difficulty. Recognizing these symptoms is crucial to avoid misdiagnosis and ensure timely and appropriate treatment for patients.