■精准医学领域致力于通过推进个性化诊断策略来改变医疗保健行业,治疗方式,和预测性评估。这是通过利用包含不同组件的广泛多维生物数据集来实现的,比如一个人的基因构成,功能属性,和环境影响。人工智能(AI)系统,即机器学习(ML)和深度学习(DL),在预测特定癌症和心血管疾病(CVD)的潜在发生方面表现出显著的功效。
■我们在PRISMA(系统评价和荟萃分析的首选报告项目)框架的指导下进行了全面的范围审查。我们的搜索策略涉及使用布尔运算符AND组合与CVD和AI相关的关键术语。2023年8月,我们对包括GoogleScholar在内的知名学术数据库进行了广泛的搜索,PubMed,IEEEXplore,ScienceDirect,WebofScience,和arXiv收集有关心血管疾病个性化医学的相关学术文献。随后,在2024年1月,我们扩展了搜索范围,包括Google等互联网搜索引擎和各种CVD网站。这些搜索在2024年3月进一步更新。此外,我们回顾了最终选定研究文章的参考文献列表,以确定任何其他相关文献.
■在进行研究的过程中,共发现了2307条记录,由来自arXiv等外部站点的564个条目和通过数据库搜索找到的1743个记录组成。消除430篇重复文章后,对剩下的1877个项目进行了相关性筛选。在这个阶段,在删除158篇无关文章和478篇数据不足的文章后,仍有1241篇文章有待进一步审查。355篇文章因无法访问而被删除,726以英语以外的语言书写,和281没有经过同行审查。因此,121项研究被认为适合纳入定性综合。在CVD的交叉点,AI,和精准医学,我们在范围审查中发现了重要的科学发现。从大的复杂模式提取,复杂的遗传数据集是人工智能算法擅长的技能,允许准确的疾病诊断和CVD风险预测。此外,这些研究发现了与心血管疾病相关的独特遗传生物标志物,提供深入了解疾病的运作和可能的治疗途径。通过整合AI和基因组学,CVD风险评估的革命性发展,使基于个体患者的遗传特征构建更精确的预测模型和个性化治疗计划成为可能。
■所采用的系统方法确保了对现有文献的全面审查和相关研究的纳入,有助于提高研究结果的稳健性和可靠性。我们的分析强调了AI解决方案的适应性和多功能性方面的关键点。在肿瘤学等非CVD领域设计的AI算法,通常包括可以修改以解决心血管问题的想法和策略。
■没有收到资金。
UNASSIGNED: The field of precision medicine endeavors to transform the healthcare industry by advancing individualised strategies for diagnosis, treatment modalities, and predictive assessments. This is achieved by utilizing extensive multidimensional biological datasets encompassing diverse components, such as an individual\'s genetic makeup, functional attributes, and environmental influences. Artificial intelligence (AI) systems, namely machine learning (ML) and deep learning (DL), have exhibited remarkable efficacy in predicting the potential occurrence of specific cancers and cardiovascular diseases (CVD).
UNASSIGNED: We conducted a comprehensive scoping
review guided by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework. Our search strategy involved combining key terms related to CVD and AI using the Boolean operator AND. In August 2023, we conducted an extensive search across reputable scholarly databases including Google Scholar, PubMed, IEEE Xplore, ScienceDirect, Web of Science, and arXiv to gather relevant academic literature on personalised medicine for CVD. Subsequently, in January 2024, we extended our search to include internet search engines such as Google and various CVD websites. These searches were further updated in March 2024. Additionally, we reviewed the reference lists of the final selected research articles to identify any additional relevant literature.
UNASSIGNED: A total of 2307 records were identified during the process of conducting the study, consisting of 564 entries from external sites like arXiv and 1743 records found through database searching. After 430 duplicate articles were eliminated, 1877 items that remained were screened for relevancy. In this stage, 1241 articles remained for additional
review after 158 irrelevant articles and 478 articles with insufficient data were removed. 355 articles were eliminated for being inaccessible, 726 for being written in a language other than English, and 281 for not having undergone peer
review. Consequently, 121 studies were deemed suitable for inclusion in the qualitative synthesis. At the intersection of CVD, AI, and precision medicine, we found important scientific findings in our scoping
review. Intricate pattern extraction from large, complicated genetic datasets is a skill that AI algorithms excel at, allowing for accurate disease diagnosis and CVD risk prediction. Furthermore, these investigations have uncovered unique genetic biomarkers linked to CVD, providing insight into the workings of the disease and possible treatment avenues. The construction of more precise predictive models and personalised treatment plans based on the genetic profiles of individual patients has been made possible by the revolutionary advancement of CVD risk assessment through the integration of AI and genomics.
UNASSIGNED: The systematic methodology employed ensured the thorough examination of available literature and the inclusion of relevant studies, contributing to the robustness and reliability of the study\'s findings. Our analysis stresses a crucial point in terms of the adaptability and versatility of AI solutions. AI algorithms designed in non-CVD domains such as in oncology, often include ideas and tactics that might be modified to address cardiovascular problems.
UNASSIGNED: No funding received.