pericardium

心包
  • 文章类型: Case Reports
    一名82岁的男性患者接受了左上叶切除术和前外侧开胸手术治疗肺癌。虽然在手术期间观察到完整的左心包缺损,未进行心包修复,因为左下叶保留,心脏被认为是稳定的.术后病理提示原发同时性双肺鳞癌(病理分期pT2a(2)N0M0IB期)。术后第8天无并发症出院。心脏向左位移和左膈抬高,怀疑膈神经麻痹,在出院后的胸部X光检查中发现。然而,在术后5个月随访时,患者的总体情况未受影响.为了评估心包修复的需要,我们比较了文献报道的肺叶切除术或全肺切除术中观察到的完全心包缺损的病例.12例中只有1例发生心包修复术后死亡,合并漏斗胸和心包缺损的病例.我们的评估表明心包修复可能是不必要的,排除复杂案件。
    An 82-year-old male patient underwent a left upper lobectomy with anterolateral thoracotomy for lung cancer. Although a complete left-pericardial defect was observed during surgery, the pericardial repair was not performed because the left lower lobe remained and the heart was considered stable. Postoperative pathological examination revealed primary synchronous double-lung squamous-cell carcinoma (pathological stage pT2a(2)N0M0 stage IB). He was discharged without complications on postoperative day 8. Leftward displacement of the heart and left diaphragmatic elevation, suspected of phrenic-nerve paralysis, were found in the chest X-ray after discharge. However, the patient\'s overall condition remained unaffected at the 5-month postoperative follow-up. To assess the need for pericardial repair, we compared cases of complete pericardial defects observed during lobectomy or pneumonectomy reported in the literature. Only one of 12 cases occurred postoperative death despite pericardial repair, and that case combined pectus excavatum and pericardial defects. Our assessment indicated that pericardial repair might not be necessary, excluding complex cases.
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  • 文章类型: Case Reports
    心外膜流出道可能是特发性室性心律失常的起源部位。这些心律失常最常见的是瓣膜周围,可以从冠状静脉系统或其他邻近结构中靶向。如右心室和左心室流出道或冠状尖区。作者报告了一例源自中间隔心外膜左心室的心外膜特发性流出道室性早搏。在这种情况下,心外膜直接入路对于识别早期局部激活和导管消融成功至关重要.
    The epicardial outflow tract can be a site of origin of idiopathic ventricular arrhythmias. These arrhythmias are most commonly perivalvular and can be targeted from within the coronary venous system or from other adjacent structures, such as the right ventricular and left ventricular outflow tracts or the coronary cusp region. The authors report a case of an epicardial idiopathic outflow tract premature ventricular contraction originating from the midseptal epicardial left ventricle. In this case, direct epicardial access was crucial to identify early local activation and achieve successful catheter ablation.
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  • 文章类型: Journal Article
    在心脏淀粉样变性患者中,心包受累很常见,多达一半的患者出现心包积液。心脏淀粉样变性心包病理的病理生理机制包括右侧充盈压的慢性升高,由于淀粉样蛋白沉积的细胞毒性作用,心肌和心包炎症,以及随后尿毒症和低蛋白血症的肾脏受累。心包积液通常很小;然而,几例危及生命的心脏填塞伴出血性积液被描述为目前的临床情况.由于淀粉样变性也可能发生缩窄性心包炎,其鉴定对同时表现出限制性心肌病征象的心脏淀粉样变性患者提出了临床挑战。多模态成像,包括超声心动图,心脏计算机断层扫描,和心脏磁共振成像,对该患者人群的评估和管理很有用。心包积液的识别对于心脏淀粉样变性患者的风险分层很重要,因为它的存在会导致预后不良。然而,针对积液本身的特定治疗很少被指出。心包填塞和缩窄性心包炎可能需要心包穿刺术和心包切除术。分别。
    In patients with cardiac amyloidosis, pericardial involvement is common, with up to half of patients presenting with pericardial effusions. The pathophysiological mechanisms of pericardial pathology in cardiac amyloidosis include chronic elevations in right-sided filling pressures, myocardial and pericardial inflammation due to cytotoxic effects of amyloid deposits, and renal involvement with subsequent uremia and hypoalbuminemia. The pericardial effusions are typically small; however, several cases of life-threatening cardiac tamponade with hemorrhagic effusions have been described as a presenting clinical scenario. Constrictive pericarditis can also occur due to amyloidosis and its identification presents a clinical challenge in patients with cardiac amyloidosis who concurrently manifest signs of restrictive cardiomyopathy. Multimodality imaging, including echocardiography, cardiac computed tomography, and cardiac magnetic resonance imaging, is useful in the evaluation and management of this patient population. The recognition of pericardial effusion is important in the risk stratification of patients with cardiac amyloidosis as its presence confers a poor prognosis. However, specific treatment aimed at the effusions themselves is seldom indicated. Cardiac tamponade and constrictive pericarditis may necessitate pericardiocentesis and pericardiectomy, respectively.
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  • 文章类型: Review
    背景:IgG4相关疾病是一种病因不明的纤维炎症性疾病,会影响多个器官系统,包括心血管系统.虽然大多数报道的心血管受累病例主要与主动脉有关,有零星的孤立心脏受累报告。
    方法:本文介绍了一例IgG4相关的全身性疾病,症状提示为限制性心肌病。随后的心脏磁共振成像显示弥漫性心肌心包受累,以心包增厚和增强为特征,伴有心外膜下和心肌浸润。考虑到我们案例中心脏受累的罕见,我们对IgG4相关疾病中各种模式的心脏受累的现有文献进行了全面回顾,以及可用于准确识别和评估的诊断方式。
    结论:本病例报告阐明了识别和评估IgG4相关全身性疾病的心脏表现以促进及时诊断和适当治疗的重要性。
    BACKGROUND: IgG4-related disease is a fibro-inflammatory disorder with an unknown etiology, which can affect multiple organ systems, including the cardiovascular system. While most reported cases of cardiovascular involvement are primarily associated with the aorta, there have been sporadic reports of isolated cardiac involvement.
    METHODS: This paper presents a documented case of IgG4-related systemic disease with symptoms indicative of restrictive cardiomyopathy. Subsequent Cardiac Magnetic Resonance imaging revealed diffuse myopericardial involvement, characterized by pericardial thickening and enhancement, accompanied by subepicardial and myocardial infiltration. Considering the rarity of cardiac involvement in our case, we conducted a thorough review of the existing literature pertaining to various patterns of cardiac involvement in IgG4-related disease, as well as the diagnostic modalities that can be employed for accurate identification and assessment.
    CONCLUSIONS: This case report sheds light on the importance of recognizing and evaluating cardiac manifestations in IgG4-related systemic disease to facilitate timely diagnosis and appropriate management.
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  • 文章类型: Meta-Analysis
    目的:感染的主动脉移植物和霉菌性动脉瘤是血管外科医师面临的最复杂的挑战之一。治疗已从解剖外旁路发展到原位重建。此外,牛心包重建(BPR)增加,由于可及性和下肢发病率降低。仍然存在,然而,使用的证据有限。目的是汇集所有已知数据,以了解霉菌性动脉瘤或感染血管移植物的BPR后的结果。
    方法:2021年11月进行了系统评价,随后对合并结果进行了计算机荟萃分析,并于2022年3月进行了最终搜索。三个数据库(EMBASE,CINAHL和PUBMED)搜索搜索词“(牛或异种)和(动脉瘤)”,根据PRISMA指南。
    结果:从九项研究中,有133例患者:67%的移植物感染;33%的霉菌性动脉瘤。57%的重建在腹主动脉中,33%在胸主动脉中。确定了158种病原体,包括金黄色葡萄球菌(23%),白色念珠菌(13%)和大肠杆菌(13%)。12%,没有发现微生物。30天死亡率为19.14%(CI10.83-28.71),晚期死亡率为19.08%(CI7.76~32.83),总死亡率为40.20%(CI29.82~50.97).一名患者术中死亡。术后30天,共有151例住院并发症。常见的并发症是急性肾功能衰竭(17%),肺炎(14%),谵妄(12%),呼吸功能不全(11%)和肾功能不全(7%)。下肢缺血低,发生在5.66%(CI0.54-13.82)的患者中。1.20%(CI0.00-7.71)的移植物通畅性丧失导致再次干预。再感染率为0.00%(CI0.00~1.21)。
    结论:这项荟萃分析强调了使用BPR和中等时间随访的低再感染和高移植物通畅性,然而,关于主动脉重建方案的长期和比较数据仍然有限.正如在这个复杂的队列中所预期的那样,并发症发生率和30日死亡率仍然很高.
    BACKGROUND: Infected aortic grafts and mycotic aneurysms represent one of the most complex challenges faced by vascular surgeons. Treatment has progressed from extra-anatomical bypass to in situ reconstruction. Additionally, bovine pericardium reconstruction (BPR) has increased, due to accessibility and reduced lower limb morbidity. There remains, however, limited evidence for its use. The aim is to pool all known data to understand outcomes following BPR of mycotic aneurysms or infected vascular grafts.
    METHODS: A systematic review was conducted in November 2021 with subsequent computerized meta-analysis of the pooled results and a final search in March 2022. Three databases, Excerpta Medica dataBASE (EMBASE), Cumulative Index of Nursing and Allied Health Literature (CINAHL), and National Institutes of Health PubMed (PubMed), were searched for the search term \"(bovine OR xenoprosthetic) AND (aneurysm)\", according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
    RESULTS: From 9 studies, there were 133 patients: 67% graft infections and 33% mycotic aneurysms. Fifty-seven percent of reconstructions were in the abdominal aorta and 33% were in the thoracic aorta. One hundred fifty-eight pathogens were identified, including Staphylococcus aureus (23%), Candida albicans (13%), and Escherichia coli (13%). In 12%, no microorganisms were identified. Thirty-day mortality was 19.14% (CI 10.83-28.71), late mortality was 19.08% (confidence interval [CI] 7.76-32.83), and overall mortality was 40.20% (CI 29.82-50.97). One patient died intraoperatively. There were a total of 151 in-hospital complications after 30 days postoperation. Common complications were acute renal failure (17%), pneumonia (14%), delirium (12%), respiratory insufficiency (11%) and renal insufficiency (7%). Lower limb ischemia was low, occurring in 5.66% (CI 0.54-13.82) of patients. Loss of graft patency leading to reintervention occurred in 1.20% (CI 0.00-7.71) of the grafts. Reinfection rate was 0.00% (CI 0.00-1.21).
    CONCLUSIONS: This meta-analysis highlights low reinfection and high graft patency using BPR with medium-length follow-up; however, there remain limited long-term and comparative data regarding options for aortic reconstruction. As expected in this complex cohort, the complication rate and 30-day mortality remain high.
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  • 文章类型: Journal Article
    钙化性纤维瘤是罕见的良性纤维瘤,很少发生在心脏中。我们报告了一名33岁的女性,她在健康检查中被发现患有良性心包肿瘤,在临床和影像学检查中高度怀疑是畸胎瘤。心脏肿瘤切除后,组织病理学特征显示,在胶原化的纤维结缔组织和间质中炎性细胞浸润的病灶中,有分散的砂膜体或钙化灶。病理诊断为钙化性纤维瘤。
    Calcifying fibrous tumors are rare benign fibrous tumors that rarely occur in the heart. We report a 33-year-old woman who was found to have a benign pericardial tumor on health checkup, which was highly suspected to be a teratoma in clinical and imaging examination. After cardiac tumor resection, histopathological features showed scattered foci of psammoma bodies or calcification among collagenized fibrous connective tissues and foci of inflammatory cell infiltration in the interstitium. The pathological diagnosis was a calcifying fibrous tumor.
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  • 文章类型: Systematic Review
    背景:Rosai-Dorfman病是一种罕见的疾病,通常表现为结节性疾病。心脏受累非常罕见,发生在0.1-0.2%的病例中,这阻碍了我们的理解。我们报告了一例没有淋巴结受累的患者与Rosai-Dorfman病(RDD)相关的心脏表现。Further,我们对文献进行了全面回顾,以巩固有关RDD心脏表现患者通常如何管理和治疗的数据.
    方法:对PubMed,WebofScience,并进行Embase以确定心脏受累的RDD病例。在确定的464项研究中,包括43例患者的42篇出版物符合标准,并纳入本综述。我们收集了病人的人口统计数据,以及他们的管理和治疗方法。此外,我们与一位出现与RDD相关的心脏质量的患者分享我们自己的经验.
    结果:在43名患者中,只有20.9%(n=9)在心脏表现之前有RDD病史.据报道,淋巴结受累率为32.6%(n=14),而结外心外受累占46.5%(n=20)。在介绍时,最常见的症状是呼吸困难(48.8%,n=21),胸部不适(41.9%,n=18),和下肢水肿(16.3%,n=7)。心脏表现最常见于右心房(41.9%,n=18)和心包(18.6%,n=8)。治疗包括全身药物治疗(34.9%,n=15)和心脏手术(39.5%,n=17)。中位随访时间为12个月(1至36个月),8例患者(18.6%)死亡。我们的病人,左心房有心脏肿块的人,接受了手术切除,过去5年无任何症状复发.
    结论:心脏相关的RDD表现的频率可能大于最初的感觉。这些结果强调了识别RDD及其心脏相关表现的重要性,促进受影响个体的及时诊断和治疗。
    BACKGROUND: Rosai-Dorfman disease is a rare condition that typically presents as a nodal disease. Cardiac involvement is extremely uncommon, occurring in 0.1-0.2% of cases, which has hindered our understanding. We report a case of Rosai-Dorfman disease (RDD) related cardiac manifestation in a patient without nodal involvement. Further, we conduct a comprehensive review of the literature to consolidate data on how patients with cardiac manifestations of RDD are typically managed and treated.
    METHODS: A systematic review of PubMed, Web of Science, and Embase was conducted to identify cases of RDD with cardiac involvement. Out of 464 studies identified, 42 publications encompassing 43 patients met the criteria and were incorporated in this review. We gathered data on patient demographics, as well as their management and treatment approaches. Additionally, we share our own experience with a patient who presented with a cardiac mass related to RDD.
    RESULTS: Out of the 43 patients, only 20.9% (n = 9) had a documented history of RDD prior to cardiac manifestations. Nodal involvement was reported in 32.6% (n = 14), while extranodal extracardiac involvement was reported in 46.5% (n = 20). Upon presentation, the most prevalent symptoms were dyspnea (48.8%, n = 21), chest discomfort (41.9%, n = 18), and lower extremity edema (16.3%, n = 7). Cardiac manifestations were most frequently found in the right atrium (41.9%, n = 18) and pericardium (18.6%, n = 8). Treatment encompassed systemic medical therapy (34.9%, n = 15) and cardiac surgery (39.5%, n = 17). The median follow-up period was 12 months (with a range of 1 to 36), and 8 patients (18.6%) experienced mortality. Our patient, who had a cardiac mass in the left atrium, underwent resection and has remained symptom-free without any recurrence for the past 5 years.
    CONCLUSIONS: The frequency of cardiac related-RDD manifestations may be greater than initially perceived. These results underscore the significance of identifying RDD and its cardiac-related presentations, facilitating timely diagnosis and treatment for affected individuals.
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  • 文章类型: Journal Article
    目的:这篇综述介绍了病因,临床表现,诊断方法,先天性心包缺损的治疗。它还强调了超声心动图的关键作用,心脏计算机断层扫描(CCT),和心脏磁共振(CMR)在诊断和管理方法中的应用。
    结果:先天性心包缺损很少见。虽然大多数病例是偶然发现的,一些病例可能与包括心脏性猝死在内的严重结局相关.由于非特异性临床表现和心电图发现,诊断通常具有挑战性。超声心动图是评估这种情况的一线影像学检查。先进的心脏成像模式,包括CCT和CMR,在建立诊断和辅助预后方面发挥重要的辅助作用。
    This review presents the etiology, clinical manifestations, diagnostic approach, and treatment of congenital pericardial defects. It also highlights the critical role of echocardiography, cardiac computed tomography (CCT), and cardiac magnetic resonance (CMR) in the diagnosis and management approach.
    Congenital pericardial defects are rare. Although most cases are found incidentally, some cases could potentially be associated with serious outcomes including sudden cardiac death. The diagnosis is often challenging due to non-specific clinical manifestations and electrocardiogram findings. Echocardiography is the first-line imaging investigation for the evaluation of this condition. Advanced cardiac imaging modalities, including CCT and CMR, play important adjuvant roles in establishing the diagnosis and assists with prognostication.
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  • 文章类型: Review
    目的:描述牛心包网(Tutopatch®)在乳房重建中的用途和优势,并比较直接乳房重建中使用的不同网状材料。
    方法:我们的研究涉及单中心,回顾性分析103例(包括114例乳房)使用牛心包牛基质行即刻植入乳房重建的患者。该手术由同一手术团队在2018年4月至2023年5月期间进行。
    结果:在中位随访时间为30.2±5.5个月后检查早期和晚期并发症的发生率。结果显示,早期并发症的发生率为9.7%,而在14.5%的病例中观察到晚期并发症。最常见的晚期并发症是血清肿形成(7.7%),其中6例无需任何手术干预即可解决。
    结论:Tutopatch®可用作肌肉的延伸以覆盖假体。它在硅胶植入物上形成额外的层,有助于减少包膜挛缩和植入物暴露等并发症。当与类似尺寸的网状材料相比时,它还代表成本显著降低85%。
    方法:本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    OBJECTIVE: To describe the usage and advantages of bovine pericardium mesh (Tutopatch®) in breast reconstruction and to compare different mesh materials used in immediate breast reconstruction.
    METHODS: Our study involved a single-center, retrospective analysis of 103 patients (comprising 114 breasts) who underwent immediate implant-based breast reconstruction using bovine pericardium bovine matrix. The procedures were performed by the same surgical team between April 2018 and May 2023.
    RESULTS: The rates of early and late complications were examined after a median follow-up period of 30.2 ± 5.5 months. The results revealed that the rates of early complications stood at 9.7%, while late complications were observed in 14.5% of the cases. The most common late complication was seroma formation (7.7%) which six were resolved without any surgical intervention.
    CONCLUSIONS: Tutopatch® can be used as an extension of the muscle to cover the prosthesis. It forms an extra layer over the silicone implant that helps to decrease the complications as capsular contracture and implant exposure. It also represents a significant 85 % reduction in cost when compared to a similar-sized mesh materials.
    METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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  • 文章类型: Systematic Review
    背景:完美的心脏瓣膜假体优化了血液动力学,降低手术发病率,持久耐用,并延长患者生存,提高生活质量。建议使用机械阀门;但是,幼儿可能需要抗凝药物治疗。在这项研究中,我们观察了主动脉瓣新开放术(AVNeo)手术治疗多种主动脉疾病的成功率和可行性.
    方法:使用方法搜索策略来全面评估AVNeo结果。布尔运算符用于组合重要的单词,例如\'OzakiProcedure,\'\'主动脉瓣新张合,\'\'AVNeo,\'和相关术语。信誉良好的数据库,如PubMed、MEDLINE,Embase,WebofScience,Scopus是我们搜索的焦点.使用关键评估技能计划工具创建的关键评估来评估研究质量。
    结果:结果总结在\'结果\'部分,其中包含描述性和批判性分析,分支,和解释。根据研究,AVNeo改善了瓣膜功能,副作用少。与Trifecta相比,主动脉瓣新阻塞具有较低的平均压力梯度和较大的平均有效孔口面积。主动脉瓣手术减少主动脉瓣反流和压力梯度。术后超声心动图显示峰值降低,平均压力梯度升高。
    结论:Ozaki方法恢复健康的层流模式,同时预防双瓣膜疾病。对于患有躯干瓣膜和先天性主动脉疾病的婴儿,应探索Ozaki手术进行瓣膜修复。用戊二醛处理的自体心包的主动脉瓣三联术导致相当大的有效孔口面积。适度的压力梯度,和很少的反流。
    Perfect heart valve prostheses have optimized hemodynamics, reduced surgical morbidity, long-lasting durability, and extended patient survival with greater quality of life. Mechanical valves are recommended; however, young children may need anticoagulant medication for life. In this study, we looked at the success rate and viability of aortic valve neocuspidization (AVNeo) surgery for a variety of aortic disorders.
    A methodical search strategy was used to fully evaluate the AVNeo results. Boolean operators were used to combine important words like \'Ozaki Procedure,\' \'Aortic Valve Neocuspidization,\' \'AVNeo,\' and associated terms. Reputable databases such as PubMed, MEDLINE, Embase, Web of Science, and Scopus were the focus of our search. Study quality was assessed using a critical evaluation created with the Critical Appraisal Skills Programme tool.
    The findings are summarized in the \'Results\' section that contains descriptive and critical analysis, ramifications, and explanations. According to research, AVNeo improved valve function and had few side effects. Aortic valve neocuspidization has a lower mean pressure gradient and a larger mean efficient orifice area than Trifecta. Aortic valve neocuspidization surgery reduces aortic valve regurgitation and pressure gradients. Postoperative echocardiograms indicated a decrease in peak and a rise in mean pressure gradient.
    The Ozaki method restores a healthy laminar flow pattern while preventing bivalvular disease. Ozaki procedure should be explored for valve repair in infants with truncal valve and congenital aortic disease. Aortic valve tricuspidization with glutaraldehyde-treated autologous pericardium results in considerable effective orifice area, modest pressure gradients, and little regurgitation.
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