pediatric intensive care

儿科重症监护
  • 文章类型: Journal Article
    目的:我们提出了12月龄以下严重细支气管炎婴儿的治疗指南,旨在为国家和国际指南中缺乏个性化的患者亚组提出一系列务实的建议。
    方法:25位法语专家,FranophonedeRéanimationetUrgencePédiatriques(法语儿科重症和急诊护理小组;GFRUP)的所有成员(阿尔及利亚,比利时,加拿大,法国,瑞士),从2021年到2022年,通过电话会议和面对面会议合作。该指南涵盖五个方面:(1)儿科重症监护病房的入院标准,(2)环境与监测,(3)喂养和水化,(4)通气支持和(5)辅助治疗。问题以患者干预比较结果(PICO)格式编写。通过PubMed在MEDLINE数据库中索引了广泛的英语和法语文献搜索,WebofScience,使用预先建立的关键字执行Cochrane和Embase。根据建议评估的等级对文本进行分析和分类,开发和评估(等级)方法。当此方法不适用时,给出了专家意见。所有专家都根据Delphi方法对这些建议进行了投票。
    结果:该小组提出了40条建议。等级方法可以应用于其中的17个(3个强,14条件性),并对其余23个给出了专家意见。在第一轮投票中,所有人都获得了强烈的批准。
    结论:这些指南涵盖了儿科重症监护病房婴儿重症细支气管炎管理的不同方面。与文献中描述的治疗严重毛细支气管炎患者的不同方法相比,我们的原始工作在监测和治疗方面提出了一种总体上侵入性较小的方法.
    We present guidelines for the management of infants under 12 months of age with severe bronchiolitis with the aim of creating a series of pragmatic recommendations for a patient subgroup that is poorly individualized in national and international guidelines.
    Twenty-five French-speaking experts, all members of the Groupe Francophone de Réanimation et Urgence Pédiatriques (French-speaking group of paediatric intensive and emergency care; GFRUP) (Algeria, Belgium, Canada, France, Switzerland), collaborated from 2021 to 2022 through teleconferences and face-to-face meetings. The guidelines cover five areas: (1) criteria for admission to a pediatric critical care unit, (2) environment and monitoring, (3) feeding and hydration, (4) ventilatory support and (5) adjuvant therapies. The questions were written in the Patient-Intervention-Comparison-Outcome (PICO) format. An extensive Anglophone and Francophone literature search indexed in the MEDLINE database via PubMed, Web of Science, Cochrane and Embase was performed using pre-established keywords. The texts were analyzed and classified according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. When this method did not apply, an expert opinion was given. Each of these recommendations was voted on by all the experts according to the Delphi methodology.
    This group proposes 40 recommendations. The GRADE methodology could be applied for 17 of them (3 strong, 14 conditional) and an expert opinion was given for the remaining 23. All received strong approval during the first round of voting.
    These guidelines cover the different aspects in the management of severe bronchiolitis in infants admitted to pediatric critical care units. Compared to the different ways to manage patients with severe bronchiolitis described in the literature, our original work proposes an overall less invasive approach in terms of monitoring and treatment.
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  • 文章类型: Journal Article
    背景:法国(2014)和美国(2017)儿科指南建议在儿科重症监护早期开始肠内营养(EN)。这项研究的目的是比较指南在儿科重症监护病房(PICU)中的适用性,并确定不适用指南的风险因素。方法:回顾性分析,单中心研究于2014年至2016年在医疗外科PICU进行.包括所有1个月至18岁的患者,其住院时间>48小时,并且在PICU住院期间至少1天进行独家EN。结果变量是2014年和2017年指南的应用,根据两项指南的定义,能量摄入量≥推荐摄入量的90%,至少1天。比较“最佳EN”与“非应用”的危险因素。两个指南的“非最佳EN”组。结果:总的来说,包括416名儿童(死亡率,8%)。36%的病例发生营养不良。平均能量摄入量为34±30.3kcalkg-1day-1。2014年和2017年指南适用于183例(44%)和296例(71%)患者,分别为(p<0.05)。按照2017年的指导方针,335例患者(81%)的肠内能量摄入被认为是“令人满意的肠内能量摄入”。血流动力学失败是两个指南均未应用的危险因素。结论:在我们的PICU中,接收的能量摄入量接近美国2017年指南建议的摄入量水平,它使用了预测性斯科菲尔德方程,似乎比2014年指南的更高建议更有用和适用。验证儿科指南的多中心研究似乎是必要的。
    Background: French (2014) and American (2017) pediatric guidelines recommend starting enteral nutrition (EN) early in pediatric intensive care. The aims of this study were to compare the applicability of the guidelines in the pediatric intensive care unit (PICU) and to identify risk factors of non-application of the guidelines. Methods: This retrospective, single-center study was conducted in a medical-surgical PICU between 2014 and 2016. All patients from 1 month to 18 years old with a length of stay >48 h and an exclusive EN at least 1 day during the PICU stay were included. The outcome variable was application of the 2014 and 2017 guidelines, defined by energy intakes ≥90% of the recommended intake at least 1 day as defined by both guidelines. The risk factors of non-application were studied comparing \"optimal EN\" vs. \"non-optimal EN\" groups for both guidelines. Results: In total, 416 children were included (mortality rate, 8%). Malnutrition occurred in 36% of cases. The mean energy intake was 34 ± 30.3 kcal kg-1 day-1. The 2014 and 2017 guidelines were applied in 183 (44%) and 296 (71%) patients, respectively (p < 0.05). Following the 2017 guidelines, enteral energy intakes were considered as \"satisfactory enteral intake\" for 335 patients (81%). Hemodynamic failure was a risk factor of the non-application of both guidelines. Conclusion: In our PICU, the received energy intake approached the level of intake recommended by the American 2017 guidelines, which used the predictive Schofield equations and seem more useful and applicable than the higher recommendations of the 2014 guidelines. Multicenter studies to validate the pediatric guidelines seem necessary.
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  • 文章类型: Journal Article
    There is a global variation in policies that define clear indications for pediatric intensive care unit (PICU) admissions. In resource-limited countries where PICU service availability is limited, the admission criteria to PICU are urgently needed to optimize the utilization of available intensive care services and to maximize patient benefit. The objective of these consensus recommendations on PICU admission criteria is to provide a framework and reference for future policy development by professional societies and governments.
    UNASSIGNED: The consensus recommendations were developed by a multidisciplinary consensus task force comprised of international experts in pediatric critical care, emergency medicine, trauma, critical care, and health policy stakeholders during the 2016 annual INDUSEM WORLD CONGRESS in Bengaluru, India.
    UNASSIGNED: A task force steering committee completed a global literature search about PICU admission criteria development, reviewed PICU admission guidelines published by a variety of professional organizations worldwide, and performed a literature review of relevant publications. The objectives of this task force is to provide a framework for validated approach to determine appropriateness of intensive care unit (ICU) admission in India (resource-limited setting) based on (a) prioritization modeling; (b) general clinical criteria; (c) clinical and objective parameters; and (d) other criteria. The expert consensus panel then discussed and ranked proposed criteria according to scientific evidence, the current standard of care, and expert opinion in the context of the Indian health system. The general subject was addressed in sections: admission criteria and benefits of different levels of care. Following the appraisal of the literature, discussion, and consensus, recommendations were written.
    UNASSIGNED: Although these are consensus recommendations, the subjects addressed encompass complex ethical and medicolegal aspects of patient care that affect daily clinical practice. The scarcity of high-quality evidence made it difficult to answer all the questions asked related to ICU admission. Despite these limitations, the members of the task force believe that these recommendations provide a comprehensive framework to guide practitioners in making informed decisions during the admission process. This publication is designed to assist in future development of health policies to ensure effective resource allocation, maximize healthcare benefits, and improve access to quality care for children.
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