osteophytes

骨赘
  • 文章类型: Case Reports
    骨赘在椎体上生长,有时形成锋利的边缘,可诱发创伤性腹主动脉损伤(TAAI)。然而,这些病例极为罕见,虽然骨赘在几乎每个人都随着年龄增长。在这里,我们报告了一例罕见的TAAI病例,原因是压缩性骨折后出现尖锐的骨赘脱位,与文献综述。一名83岁的男子在跌倒后出现背部疼痛,随后出现休克。他到达时乳酸水平升高,尽管我们无法确定休克的原因。增强计算机断层扫描(CT)显示腰椎压缩性骨折,穿透腹主动脉的尖锐骨赘,造影剂喷向腹膜后。我们立即输血,连续服用去甲肾上腺素来维持他的生命体征,并咨询了血管外科医生和放射科医生以安排紧急手术。然而,手术室没有立即可用。我们试图疏散创伤中心,由于COVID-19的爆发,这需要时间。此后,病人的病情恶化,导致无脉电活动,他在抵达后3小时去世。之后,在与腹主动脉接触的腰椎中观察到先前的CT图像和尖锐的骨赘。只有八份报告显示主动脉被骨赘损伤。从我们的审查来看,与普通TAAI的比例不同,由于强大的外力造成的伤害相对较小。没有具体症状,骨赘的椎体水平集中在Th12-L3。主动脉损伤最常见的形态是假性动脉瘤的形成。此外,其中五名患者出现出血。考虑到这些以前的报告,当患者的CT图像显示骨赘时,无论损伤机制如何,我们都应注意椎体前的主动脉。
    Osteophytes grow on vertebral bodies and sometimes form a sharp edge, which can induce traumatic abdominal aortic injury (TAAI). However, these cases are extremely rare, although osteophytes grow in almost everyone with age. Herein, we report a rare case of TAAI due to a sharp osteophyte dislocation following a compression fracture, with a literature review. An 83-year-old man presented with back pain after a fall and subsequently developed shock. His lactate level was elevated on arrival, although we could not identify the cause of the shock. Enhanced computed tomography (CT) revealed a compression fracture of the lumbar spine, a sharp osteophyte penetrating the abdominal aorta, and contrast media spurting to the retroperitoneum. We immediately transfused, administered continuous noradrenaline to maintain his vital signs, and consulted a vascular surgeon and radiologist to arrange for an emergency operation. However, the operating room was not immediately available. We tried to evacuate a trauma center, which took time due to the COVID-19 outbreak. Thereafter, the patient\'s condition deteriorated, resulting in a pulseless electrical activity, and he passed away 3 h after arrival. Afterward, the previous CT image and a sharp osteophyte were observed in the lumbar vertebrae in contact with the abdominal aorta. There were only eight reports where the aorta was injured by osteophytes. From our review, unlike the proportion of common TAAI, injuries due to strong external forces were relatively small. There was no specific symptom, and the vertebral levels of osteophytes were concentrated in Th12-L3. The most common morphology of aorta injuries is pseudoaneurysm formation. Moreover, five of the patients developed hemorrhage. Considering these previous reports, we should pay attention to the aorta in front of the vertebral bodies regardless of the mechanism of injury when a CT image of patients shows osteophytes.
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  • 文章类型: Case Reports
    声带麻痹发生在迷走神经或其远端分支的功能,喉返神经,减少或缺席。双侧声带麻痹可表现为不同程度的严重程度,有时是致命的。颈部骨赘是双侧声带麻痹的罕见原因,只有少数病例报告。一名68岁的男子因跌倒后意识障碍而被带到急诊室。头部CT扫描显示有多个头盖骨和脑损伤,患者接受了神经外科保守治疗。受伤后的第二天,出现吞咽困难和构音障碍。入学的第三天,两条声带两侧固定在旁正中位置,病人几乎被痰窒息。CT扫描显示颅内病变逐渐好转,但是声带麻痹仍然存在。进行了颈部CT扫描以调查声带麻痹的原因,显示颈椎骨赘压迫气管食管沟和声门。病人被转院接受康复治疗,尽管双侧声带麻痹仍然存在。虽然罕见,临床医生需要意识到宫颈骨赘会导致声带麻痹,当与进一步的创伤相结合时可能会表现出来。同样重要的是要注意,创伤性声带麻痹可以延迟。
    Vocal fold paralysis occurs when the function of the vagus nerve or its distal branch, the recurrent laryngeal nerve, is diminished or absent. Bilateral vocal fold paralysis can present with varying degrees of severity and is sometimes fatal. Cervical osteophytes are a rare cause of bilateral vocal fold paralysis, with only a few cases reported. A 68-year-old man was brought to the emergency department because of a disturbance in consciousness following a fall. A CT scan of the head showed multiple cranium and brain injuries, and the patient was treated conservatively by neurosurgery. The day after the injury, dysphagia and dysarthria appeared. On the third day of admission, both vocal cords were fixed bilaterally in the paramedian position, and the patient was nearly choking on sputum. A CT scan showed that the intracranial lesions gradually improved, but the vocal cord paralysis remained. A cervical CT scan was performed to investigate the cause of the vocal cord paralysis, which revealed that cervical vertebral osteophytes were compressing the tracheoesophageal groove and the glottis. The patient was transferred to the hospital for rehabilitation, although bilateral vocal cord paralysis remained. Although rare, clinicians need to be aware that cervical osteophytes can cause vocal fold paralysis, which may be manifested when combined with further trauma. It is also important to note that traumatic vocal cord paralysis can be delayed.
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  • 文章类型: Case Reports
    吞咽困难是一种常见症状,具有各种潜在病因,使其管理具有挑战性,即使是经验丰富的医生。颈椎骨赘的存在通常会阻碍吞咽,使喉部移位,导致喉咙痛。我们描述了一例85岁的男性,他有两年的进行性吞咽困难病史,在过去的两个月里,尤其是固体食物和液体,提示耳鼻喉科评估。尽管之前有调查,包括正常胃镜检查和经验性疼痛管理,进一步评估显示下咽部肿块膨出,提示宫颈骨赘.保守管理,包括言语和吞咽疗法,饮食调整,和药物干预,在没有手术干预的情况下,症状明显改善。此病例证明了保守治疗措施治疗宫颈骨赘所致吞咽困难的有效性。强调多学科方法对优化患者护理的重要性。
    Dysphagia is a common symptom with various underlying etiologies, making its management challenging even for experienced physicians. The presence of osteophytes in the cervical spine may often impede swallowing, displace the larynx, and cause a sore throat. We describe a case of an 85-year-old male who presented with a two-year history of progressive dysphagia, exacerbated over the last two months, especially with solid foods and liquids, prompting an ENT evaluation. Despite prior investigations, including normal gastroscopy and empirical pain management, further assessment revealed bulging masses in the hypopharynx indicative of cervical osteophytes. Conservative management, including speech and swallow therapy, dietary modifications, and pharmacological interventions, resulted in significant symptom improvement without surgical intervention. This case demonstrates the effectiveness of conservative treatment measures in treating dysphagia caused by cervical osteophytes, emphasizing the significance of a multidisciplinary approach for optimal patient care.
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  • 文章类型: Case Reports
    膝盖严重锁定是一种需要紧急骨科干预的无行为能力状况。膝关节锁定的常见原因包括半月板撕裂,前交叉韧带(ACL)断裂的残端,松散的身体,骨软骨损伤.本报告描述了一个罕见的情况下,一个严重锁定的膝盖,由于同时存在一个松散的身体和一个退行性骨赘,强调成功管理所采用的诊断挑战和治疗策略。值得注意的是,根据我们的知识,没有以前的报告记录相同的病因。
    An acutely locked knee is an incapacitating condition that requires urgent orthopedic intervention. Common causes of the locked knee include a tear of the meniscus, stump of a ruptured anterior cruciate ligament (ACL), loose body, and osteochondral injury. This report describes a rare case of an acutely locked knee due to the concurrent presence of a loose body and a degenerative osteophyte, highlighting the diagnostic challenges and treatment strategies employed for successful management. Notably, to our knowledge, there is no preceding report documenting the same etiology.
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  • 文章类型: Case Reports
    由于颈椎前段广泛骨化引起的吞咽困难很少发生,通常归因于弥漫性特发性骨骼骨肥大(DISH)。我们介绍了一名74岁女性吞咽困难的病例,该病例很可能是由于假性甲状旁腺功能减退症1a型(PHP1a)的骨化所致。PHP1a是一种罕见的,由GNAS1基因突变引起的常染色体显性疾病。我们的患者具有PHP1a的特征性表型特征,也被称为奥尔布赖特遗传性骨营养不良(AHO),在没有遗传证实的情况下被诊断出来。她接受了饮食措施和观察的保守治疗,并在6个月的随访中报告了持续的吞咽困难症状。这是第一个在PHP1a中描述吞咽困难的案例,其表现与DISH相似。
    Dysphagia due to extensive ossification at anterior segments of the cervical spine is a rare occurrence and is usually attributable to diffuse idiopathic skeletal hyperostosis (DISH). We present the case of a 74-year-old female with dysphagia most likely due to ossification in pseudohypoparathyroidism type 1a (PHP1a). PHP1a is a rare, autosomal dominant disorder caused by mutations in the GNAS1 gene. Our patient had characteristic phenotype features of PHP1a, also known as Albright\'s hereditary osteodystrophy (AHO), which was diagnosed without genetic confirmation. She was conservatively treated with dietary measures and observation, and reported persisting symptoms of dysphagia at six-month follow-up. This is the first case to describe dysphagia in PHP1a with a similar presentation to DISH.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    OBJECTIVE: The objective of this cross-sectional case-control study was to determine the prevalence and size of marginal and subarticular osteophytes in patients with osteoarthritis (OA), and to compare these to that of a control group.
    METHODS: We investigated femoral heads from 25 patients with OA following hip replacement surgery, and 25 femoral heads from a control group obtained post-mortem. The area and boundary length of the femoral head, marginal osteophytes, and subarticular osteophytes were determined with histomorphometry. Marginal osteophytes were defined histologically as bony projections at the peripheral margin of the femoral head, while subarticular osteophytes were defined as areas of bone that expanded from the normal curvature of the femoral head into the articular cartilage.
    RESULTS: The prevalence of OA patients with marginal- and subarticular osteophytes were 100 and 84%, respectively. Whereas the prevalence of the participants in the control group with marginal- and subarticular osteophytes were 56 and 28%, respectively. The area and boundary length of marginal osteophytes was (median (Interquartile range)) 165.3mm2 (121.4-254.0) mm2 and 75.1 mm (50.8-99.3) mm for patients with OA compared to 0 mm2 (0-0.5) mm2 and 0 mm (0-0.5) mm for the control group (P <  0.001). For the subarticular osteophytes, the area and boundary length was 1.0 mm2 (0-4.4) mm2 and 1.4 mm (0-6.5) mm for patients with OA compared to 0 mm2 (0-0.5) mm2 and 0 mm (0-0.5) mm for the control group (P <  0.001).
    CONCLUSIONS: As expected, both marginal- and subarticular osteophytes at the femoral head, were more frequent and larger in patients with OA than in the control group. However, in the control group, subarticular osteophytes were more prevalent than expected from the minor osteophytic changes at the femoral head margin, which may suggest that subarticular osteophytes are an early degenerative phenomenon that ultimately might develop into clinical osteoarthritis.
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  • 文章类型: Journal Article
    UNASSIGNED: Osteochondral lesions (OCLs) and bony impingement are common secondary lesions of chronic lateral ankle instability (CLAI), but the risk factors that predict OCLs and bony impingement are unknown.
    UNASSIGNED: To analyze the risk factors for the development of OCLs and osteophytes in patients with CLAI.
    UNASSIGNED: Case-control study; Level of evidence, 3.
    UNASSIGNED: Patients diagnosed with CLAI at our institution from June 2007 to May 2018 were enrolled. The assessed potential risk factors were age, sex, postinjury duration, body mass index, injury side, and ligament injury type (isolated anterior talofibular ligament [ATFL] injury, isolated calcaneofibular ligament [CFL] injury, or concomitant ATFL and CFL injuries). Univariate and multivariate logistic regression analyses were performed to evaluate the association between these factors and the presence of OCLs and osteophytes.
    UNASSIGNED: A total of 1169 patients with CLAI were included; 436 patients (37%) had OCLs and 334 (31%) had osteophytes. The presence of OCLs was significantly associated with the presence of osteophytes (P < .001). Male sex and older age were significantly associated with the presence of OCLs in the medial and lateral talus. A postinjury duration of 5 years or longer was significantly associated with the presence of OCLs in the medial talus (odds ratio [OR], 1.532; 95% CI, 1.023-2.293; P = .038) but not in the lateral talus. ATFL and CFL injuries were both significantly associated with the presence of lateral OCLs. Risk factors for the presence of osteophytes were male sex, older age, postinjury duration 5 years or longer, and CFL injury. Patients with concomitant ATFL and CFL injuries were significantly more likely to have osteophytes than were patients with single-ligament injuries (P = .018).
    UNASSIGNED: Risk factors for OCLs and osteophytes were postinjury duration of 5 years or longer, older age, and male sex. ATFL injury was associated with the presence of lateral OCLs, whereas CFL injury was associated with the presence of lateral OCLs and osteophytes. Patients with these risk factors should be closely monitored and treated to reduce the incidence of ankle arthritis.
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  • 文章类型: Journal Article
    BACKGROUND: Surgical strategy of multisegmental spinal fixation that includes atlantoaxial joint for patients having cervical spondylosis-related symptoms of severe myelopathy is analyzed.
    OBJECTIVE: Surgical outcome of patients presenting with \"severe\" symptoms of cervical myelopathy having multisegmental degenerative cervical spondylosis and treated by multisegmental spinal fixation is analyzed. Atlantoaxial joint was included in the fixation construct in majority of patients. No bone, soft tissue, osteophyte, or disc resection for decompression was done.
    METHODS: Sixty-four patients having multisegmental cervical spondylosis who presented with symptoms of severe myelopathy were surgically treated during the period from March 2013 to December 2018. On the basis of the concept that instability is the primary cause of spinal degeneration, multisegmental spinal fixation was done in all patients. Atlantoaxial joint was included in the fixation construct in 48 patients. The levels of spinal fixation were determined on the basis of direct observation of facet joints and by manual manipulation and were guided by the presenting clinical features and radiological information. Clinical monitoring was done using Goel clinical grading, modified Japanese Orthopedic Association Score, and visual analog score parameters. Patient satisfaction index assessed the functional and symptomatic improvement.
    RESULTS: During the follow-up that ranged from 6 to 75 months, all patients improved in their clinical status. Fifty-five (85.9%) patients could walk independently or with mild support.
    CONCLUSIONS: Multisegmental spinal fixation that includes atlantoaxial joint in most patients forms a rational treatment strategy for patients of cervical spondylosis presenting with severe symptoms of myelopathy.
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  • 文章类型: Journal Article
    这项研究的目的是确定解剖和病理宫颈结构与摄入异物(FBs)的嵌塞之间的关系。以前已经讨论了这种结构对吞咽的影响,然而,它们对FB嵌塞的贡献尚未研究。这是一项回顾性病例对照研究,对2008-2014年期间进行了计算机断层扫描(CT)扫描的171例患者进行了回顾性病例对照研究:57例食管或下咽FB;其他114例包括对照组,使用“邻居控制”方法选择。检查CT扫描以测量宫颈结构。病例组和对照组平均年龄分别为63±13岁和55±17岁,分别(p值=0.003)。年龄是唯一表现出显著差异的人口统计学或临床特征。总的来说,24例患者有宫颈骨赘:28%(16)受影响的FB,与对照组的7%(8)相比(p值<0.001)。在患有骨赘和阻生FBs的患者中,62.5%的FB停留在与其骨赘相对应的椎骨水平,而另外18.75%的人在骨赘上方的三个椎骨水平内有FB。逐步logistic回归显示骨赘是一个显著的因素,与年龄无关(p值=0.004)。在存在骨赘的情况下,FB嵌塞的调整后比值比为4.04。腹侧宫颈骨赘增加上消化道FB嵌塞的风险。这种风险与年龄无关。这些发现对预防医学有价值,并强调在复发性FB嵌塞患者中寻找脊柱变化的重要性。
    The aim of this study is to define the relationship between anatomical and pathological cervical structures and the impaction of ingested foreign bodies (FBs). The effects of such structures on deglutition have been previously discussed, however their contribution to FB impaction has not yet been examined. This was a retrospective case-control study of 171 patients who underwent computed tomography (CT) scans over the period 2008-2014: 57 patients with an esophageal or hypopharyngeal FB; the other 114 comprised the control group, selected using the \'neighbor control\' method. CT scans were reviewed for measurements of cervical structures. The mean age was 63 ± 13 years and 55 ± 17 years in the case and control groups, respectively (p-value = 0.003). Age was the only demographic or clinical characteristic which demonstrated a significant difference. Overall, 24 patients had cervical osteophytes: 28 %(16) with an impacted FB, compared with 7 %(8) from the control group (p-value < 0.001). Of the patients with osteophytes and impacted FBs, 62.5 % had the FB lodged at a vertebral level corresponding to their osteophytes, while another 18.75 % had the FB within three vertebral levels above the osteophytes. Stepwise logistic regression revealed that osteophytes were a significant factor, independent of older age (p-value = 0.004). Adjusted odds ratio for FB impaction in the presence of osteophytes was 4.04. Ventral cervical osteophytes increase the risk for FB impaction in the upper digestive tract. This risk is independent of older age. These findings can be of value in preventive medicine, and emphasize the importance of looking for spinal changes in patients with recurrent FB impaction.
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