口腔癌通常先于口腔潜在恶性疾病(OPMD),早期发现可以降低疾病的发生。大多数OPMD在早期阶段无症状,可以在常规口腔检查中检测到。尽管只有一部分OPMD可能转化为口腔鳞状细胞癌(OSCC),它们可以作为替代临床病变,用于识别有发生OSCC风险的个体.目前,缺乏关于OPMD的具体干预措施和管理的科学证据,并且在其管理方面没有共识。召开了与专家小组的共识会议,以制定OPMD的临床实践指南和管理策略建议。对医学数据库中的文献进行了综述,以提供最佳证据并提供OPMD管理建议。
Oral cancer is usually preceded by oral potentially malignant disorders (OPMDs) and early detection can downstage the disease. The majority of OPMDs are asymptomatic in early stages and can be detected on routine oral examination. Though only a proportion of OPMDs may transform to oral squamous cell carcinoma (OSCC), they may serve as a surrogate clinical lesion to identify individuals at risk of developing OSCC. Currently, there is a scarcity of scientific evidence on specific interventions and management of OPMDs and there is no
consensus regarding their management. A
consensus meeting with a panel of experts was convened to frame
guidelines for clinical practices and recommendations for management strategies for OPMDs. A review of literature from medical databases was conducted to provide the best possible evidence and provide recommendations in management of OPMDs.