non-diabetic patients

  • 文章类型: Journal Article
    牙周炎是糖尿病的第六大长期并发症,可损害糖尿病患者的代谢控制。同时患有糖尿病和牙周病的患者面临着管理这两种慢性疾病的挑战,每一个都可能影响到另一个。这项研究的目的是确定和比较在拉各斯一家大型三级医院就诊的糖尿病和非糖尿病患者中牙周炎的患病率和口腔卫生习惯,尼日利亚。
    这是一项横断面比较研究,涉及110名40岁及以上的糖尿病患者和110名非糖尿病患者。使用系统抽样方法,分别从拉各斯一家大型三级医院的糖尿病和普通医学门诊诊所招募他们。使用面试官管理的问卷收集数据。此外,使用简化的牙周检查进行糖化血红蛋白的血液检查和口腔检查。比较两组牙周炎的患病率和严重程度以及口腔卫生习惯。使用IBMSPSS版本21软件对数据进行分析。
    糖尿病患者的牙周炎患病率100(90.9%)高于非糖尿病患者79(71.8%),这具有统计学意义(p<0.001)。两组牙周炎的严重程度也在统计学上较高54(49.1%)35(31.8%)p<0.001。
    与非糖尿病患者相比,糖尿病患者的牙周炎患病率更高,更为严重。两组的口腔卫生习惯均无统计学意义p>0.05。应针对糖尿病患者开展口腔健康教育计划,以预防和控制牙周炎。
    UNASSIGNED: periodontitis is the sixth leading long-term complication of diabetes mellitus which can impair diabetic patients\' metabolic control. Patients with both diabetes mellitus and periodontal disease present with the challenge of managing these two chronic diseases, each of which may impact the other. The aim of this study was to determine and compare the prevalence of periodontitis and oral hygiene practices among diabetic and non-diabetic patients attending a large tertiary hospital in Lagos, Nigeria.
    UNASSIGNED: this was a cross-sectional comparative study involving 110 diabetics and 110 non-diabetic patients aged 40 years and above. They were recruited from the diabetes and general medical out-patient clinics respectively in a large tertiary hospital in Lagos using a systematic sampling method. Data was collected using an interviewer-administered questionnaire. In addition, blood tests for glycated haemoglobin and oral examination using a simplified periodontal examination were conducted. The prevalence and severity of periodontitis and oral hygiene practices were compared between both groups. Data were analyzed with IBM SPSS version 21 Software.
    UNASSIGNED: the prevalence of periodontitis was higher among the diabetics 100 (90.9%) compared to the non-diabetic patients 79 (71.8%), and this was statistically significant (p<0.001). Severity of periodontitis among both groups was also statistically high 54 (49.1%) vs. 35 (31.8%) p<0.001.
    UNASSIGNED: the prevalence of periodontitis was higher and more severe among diabetics compared to non-diabetics. Oral hygiene practices in both groups are not statistically significant p>0.05. Oral health education programs targeted at diabetic patients should be carried out to prevent and control periodontitis.
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  • 文章类型: Journal Article
    背景:高血糖是有和没有糖尿病(DM)的患者肠外营养(PN)的常见并发症。这项研究的目的是评估有和没有DM病史的手术患者接受PN的基础加校正胰岛素的血糖控制质量。
    方法:对2013年1月至2015年12月期间应用的方案进行回顾性评估。在先前患有DM且没有DM病史的患者中,胰岛素剂量开始于0.4和0.3IU/kg/天,分别,目标血糖(BG)<180mg/dl。平均BG水平,还评估了不同PN日的胰岛素总日剂量(TDD)和低血糖事件(<70mg/dl).
    结果:评估了41例既往2型DM患者和39例非DM患者。两组的血糖控制如下:在最初的48小时内(230.4±67vs.189.4±38毫克/分升,p=0.002);在中点(224.6±58vs.181.3±27mg/dl,p=0.003);TPN结束前48小时(196.4±43vs.169.8±40mg/dl,p=0.004)。DM患者的胰岛素TDD为0.5±0.3U/kg/天,非DM患者为0.37±0.3单位/kg/天(p<0.05)。共有18例患者出现低血糖事件,没有组间的差异。
    结论:基础校正胰岛素方案是治疗PN非危重手术患者高血糖的替代方法。
    BACKGROUND: Hyperglycemia is a frequent complication of parenteral nutrition (PN) in patients both with and without diabetes mellitis (DM). The aim of this study was to evaluate the quality of glucose control achieved with basal plus-correction insulin in surgical patients with and without a history of DM receiving PN.
    METHODS: Retrospective evaluation of a protocol applied during the period of January 2013-December 2015. The insulin dose was started at 0.4 and 0.3 IU/kg/day in patients with previous DM and without a history of DM, respectively, and the target blood glucose (BG) was < 180 mg/dl. Mean BG levels, insulin total daily dose (TDD) and hypoglycemic (< 70 mg/dl) events on different days of PN were also evaluated.
    RESULTS: Forty-one patients with previous type 2 DM and 39 without DM were evaluated. Glycemic control in both groups was as follows: during the first 48 h (230.4 ± 67 vs. 189.4 ± 38 mg/dl, p = 0.002); at the midpoint (224.6 ± 58 vs. 181.3 ± 27 mg/dl, p = 0.003); 48 h before ending TPN (196.4 ± 43 vs. 169.8 ± 40 mg/dl, p = 0.004). Insulin TDD was 0.5 ± 0.3 U/kg/day in patients with DM and 0.37 ± 0.3 units/kg/day in those without DM (p < 0.05). A total of 18 patients experienced hypoglycemic events, without differences between the groups.
    CONCLUSIONS: A basal-correction insulin regimen is an alternative method for managing hyperglycemia in non-critically ill surgical patients on PN.
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