■特发性Castleman病转化为弥漫性大B细胞淋巴瘤具有侵袭性过程并可导致死亡。因此,需要早期诊断和干预。
■特发性Castleman病转化为非霍奇金淋巴瘤具有侵袭性病程,预后不良,和高死亡率。因此,早期诊断和干预是必要的。在像尼泊尔这样的发展中国家,传染病,特别是TB,很高,伴随感染使病程恶化。由于临床表现可能相似,因此也带来了诊断挑战。
UNASSIGNED: Idiopathic Castleman disease transforming into Diffuse Large B-cell Lymphoma has an aggressive course and can lead to mortality. Hence, early diagnosis and intervention are required.
UNASSIGNED: Idiopathic Castleman disease transforming into non-Hodgkin lymphoma has an aggressive course, poor prognosis, and high mortality rate. Hence, early diagnosis and intervention are necessary. In a developing country like Nepal, where infectious diseases, particularly TB, are high, concomitant infection worsens the disease course. It also poses a diagnostic challenge as the clinical presentation may be similar.