nociception

伤害感受
  • 文章类型: Journal Article
    将下腰痛分类为以显性伤害性为特征的可能性,神经病,或有害机制是一个临床相关的问题。初步证据表明,这些下腰痛表型可能对治疗有不同的反应;然而,在提出具体建议之前,必须做更多的研究。因此,腰背痛表型鉴定(BACPAP)联盟由来自13个国家(五大洲)和29个机构的36名临床医生和研究人员组成,应用改进的NominalGroup技术方法来制定国际和多学科共识建议,为识别下腰痛患者的显性疼痛表型提供指导。并可能适应疼痛管理策略。BACPAP联盟的建议还旨在通过建立神经性和伤害性疼痛的既定临床标准,为未来的临床研究提供方向。BACPAP联盟的共识建议是该过程中必要的早期步骤,以确定基于疼痛表型的个性化疼痛药物对于下腰痛管理是否可行。因此,这些建议尚未准备好在临床实践中实施,直到产生针对这些下腰痛表型的其他证据.
    The potential to classify low back pain as being characterised by dominant nociceptive, neuropathic, or nociplastic mechanisms is a clinically relevant issue. Preliminary evidence suggests that these low back pain phenotypes might respond differently to treatments; however, more research must be done before making specific recommendations. Accordingly, the low back pain phenotyping (BACPAP) consortium was established as a group of 36 clinicians and researchers from 13 countries (five continents) and 29 institutions, to apply a modified Nominal Group Technique methodology to develop international and multidisciplinary consensus recommendations to provide guidance for identifying the dominant pain phenotype in patients with low back pain, and potentially adapt pain management strategies. The BACPAP consortium\'s recommendations are also intended to provide direction for future clinical research by building on the established clinical criteria for neuropathic and nociplastic pain. The BACPAP consortium\'s consensus recommendations are a necessary early step in the process to determine if personalised pain medicine based on pain phenotypes is feasible for low back pain management. Therefore, these recommendations are not ready to be implemented in clinical practice until additional evidence is generated that is specific to these low back pain phenotypes.
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