neurogenic

神经性
  • 文章类型: Case Reports
    囊性淋巴管瘤(CL)是一种罕见的先天性淋巴系统畸形,经常发生在头部,脖子,或纵隔,可能导致吞咽困难或呼吸困难等压迫症状,在极少数情况下,神经源性胸廓出口综合征(nTOS)。本报告详述了一例38岁男性,有4年左下颈部肿块病史,在过去的六个月里,他的左前臂有刺痛。检查发现左侧锁骨上囊性肿块,影像学显示CL压迫神经血管结构。患者通过左锁骨上入路成功进行了完整的手术切除。组织病理学证实CL,在19个月内没有观察到复发。该病例突出表明,成人表现的颈胸CL可引起压力症状,包括nTOS。它还强调了多模式诊断方法将其与其他颈部肿块区分开的作用,并且锁骨上方法可以有效地去除囊肿,特别是当下部延伸不深并且周围没有炎症时,从而导致缓解压力和防止复发。
    Cystic lymphangioma (CL) is an uncommon congenital malformation of the lymphatic system, often occurring in the head, neck, or mediastinum, potentially causing compression symptoms like dysphagia or dyspnea, and in rare cases, neurogenic thoracic outlet syndrome (nTOS). This report details a case of a 38-year-old male with a four-year history of a left lower neck mass, experiencing tingling in his left forearm over the last six months. The examination revealed a left supraclavicular cystic mass, with imaging suggesting CL compressing neurovascular structures. The patient underwent successful complete surgical excision through a left supraclavicular approach. Histopathology confirmed CL, with no recurrence observed over 19 months. The case highlights that cervicothoracic CL with adult presentation can cause pressure symptoms including nTOS. It also underscores the role of a multimodal diagnostic approach to differentiate it from other neck masses and that a supraclavicular approach can effectively remove the cyst, especially when the lower extension is not deep and there is no surrounding inflammation, thereby leading to relieving pressure and preventing recurrence.
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  • 文章类型: Case Reports
    以下病例报告分析了一名体外膜氧合(ECMO)患者,由于COVID-19肺炎而患有严重的急性呼吸窘迫综合征(ARDS)。ARDS被定义为肺部的弥漫性和炎症性损伤;当动脉血氧张力与吸入氧气的比例(PaO2/FiO2)等于或低于100mmHg时,将其分类为严重。为了确定患者是否适合使用ECMO治疗,使用了ELSO标准;在这种情况下,患者符合低氧性呼吸衰竭的标准(PaO2/FiO2<80mmHg),包括,在没有禁忌症的情况下,俯卧定位的试验。住院期间,患者出现了中心性尿崩症(CDI),可能是由于缺氧对中枢神经系统造成的损害。关于COVID-19引起的这种并发症的报道很少。这个案子是关于一个39岁的女人,在有创机械通气(IMV)开始后6天开始使用ECMO,因为严重的ARDS。在ECMO的第五天,患者在24小时内开始出现7L的多尿。进行了一系列临床旁研究,但是没有发现中枢神经系统病变的证据。开始去氨加压素治疗后,ARDS得到解决,多尿停止了;有了这个,CDI被诊断。有许多继发于COVID-19感染演变的并发症,其中一些还没有得到很好的解释。
    The following case report analyses a patient with extracorporeal membrane oxygenation (ECMO), who suffered from a severe Acute Respiratory Distress Syndrome (ARDS) due to COVID-19 pneumonia. ARDS is defined as a diffuse and inflammatory injury of the lungs; classifying this as severe when the ratio of arterial oxygen tension to a fraction of inspired oxygen (PaO2/FiO2) is equal to or lower than 100 mmHg. To decide if the patient was suitable for the use of ECMO therapy, the ELSO criteria were used; and in this case, the patient matched with the criteria of hypoxemic respiratory failure (with a PaO2/FiO2 < 80 mmHg) after optimal medical management, including, in the absence of contraindications, a trial of prone positioning. During hospitalization, the patient presented a Central Diabetes Insipidus (CDI), probably explained by the damage hypoxia generated on the central nervous system. There are few reports of this complication produced by COVID-19. The case is about a 39-year-old woman, who started with ECMO 6 days after the beginning of Invasive Mechanical Ventilation (IMV), because of a severe ARDS. On the fifth day of ECMO, the patient started with a polyuria of 7 L in 24 h. A series of paraclinical studies were made, but no evidence of central nervous system lesions was found. After treatment with desmopressin was initiated and the ARDS was solved, polyuria stopped; with this, CDI was diagnosed. There are many complications secondary to the evolution of COVID-19 infection, and some of them are not yet well explained.
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  • 文章类型: Case Reports
    背景:已经报道了卵巢中的神经源性单胚层畸胎瘤(NMT),而不是骨骼。病例报告:一名6岁女孩在右肩胛骨有一个偶然发现的病变。移除后,这是一个以脉络丛为主的NMT。该疾病已经31个月没有进展。结论:骨内也可发生神经源性单胚层畸胎瘤。
    Background: Neurogenic monodermal teratomas (NMTs) have been reported in the ovaries but not from bone. Case Report: A 6-year-old girl had an incidentally discovered lesion in the right scapula. Upon removal, it was an NMT with predominant choroid plexus. The disease had not progressed for 31 months. Conclusion: Neurogenic monodermal teratomas can also occur in bone.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Case Reports
    正中弓状韧带综合征(MALS)是一种罕见的神经源性胃肠道(GI)症状,是由于正中弓状韧带压迫腹腔干和腹腔丛引起的。MALS的特征是非特异性症状,包括恶心,呕吐,腹泻,腹胀,由于厌恶食物而导致的无意减肥,和餐后上腹部腹痛。我们提出了一个非典型的案例,慢性MALS困扰临床医生十多年,并导致各种误诊,包括早发性帕金森病。在MALS可能出现的一系列症状中,餐后上腹痛是一种典型的症状,增加了诊断的怀疑指数;然而,我们的患者没有典型的餐后上腹痛症状以及非特异性胃肠道症状和晕厥的存在,进一步影响了临床医生诊断MALS的能力.经进一步调查,我们阐明了加巴喷丁之间的联系,我们的病人长期开处方,及其在降低胃肠道神经源性超敏反应中的功效。我们的案例和加巴喷丁用于减少MALS引起的神经源性疼痛的含义代表了MALS治疗方式文献的新补充,并阐明了继续研究使用加巴喷丁作为症状调节剂用于非手术和术前治疗的新途径。
    Median arcuate ligament syndrome (MALS) is a rare constellation of neurogenic gastrointestinal (GI) symptoms resulting from compression of the celiac trunk and celiac plexus by the median arcuate ligament. MALS is characterized by nonspecific symptoms including nausea, vomiting, diarrhea, bloating, unintentional weight loss due to food aversion, and postprandial epigastric abdominal pain. We present a case of atypical, chronic MALS that confounded clinicians for over a decade and led to various misdiagnoses, including early-onset Parkinson\'s disease. Of the constellation of symptoms that MALS may present with, postprandial epigastric pain is a classic symptom and increases the index of suspicion for the diagnosis; however, the absence of the classic symptom of postprandial epigastric pain and the predomination of nonspecific GI symptoms and syncope in our patient further clouded clinicians\' ability to diagnose MALS. Upon further investigation, we elucidated a link between gabapentin, which our patient was chronically prescribed, and its efficacy in decreasing neurogenic hypersensitivity in the GI tract. Our case and the implications of gabapentin use to decrease neurogenic pain from MALS represents a novel addition to the literature on MALS treatment modalities and elucidates new avenues for continued research in the use of gabapentin as a symptom-modifying agent in the nonoperative and preoperative treatment of MALS.
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  • 文章类型: Journal Article
    纵隔副神经节瘤表现为大型哑铃瘤是一种罕见的实体。我们报告了一例47岁的女性,患有脊柱疼痛和散发性下肢轻瘫。影像学检查显示,后纵隔有大量肿块,右椎间孔延伸。为了获得优异的结果,包括胸外科和神经外科医生团队在内的共同努力是必要的.成功完成了完整的切除,没有椎板切除术。手术过程顺利。
    Mediastinal paraganglioma presented as a large dumbbell tumor is a rare entity. We report a case of a 47 year old woman who suffered from spinal pain and sporadic lower limb paresis. The imaging studies showed a voluminous mass occupying the posterior mediastinum with right foraminal extension. For excellent results, a combined effort was necessary including thoracic and neurosurgeons teams. Complete resection was successfully performed without laminectomy. The operative course was uneventful.
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  • 文章类型: Case Reports
    有症状的双侧并列神经节囊肿在退化的脊柱中相对少见。文献描述了16例双侧神经节或滑膜囊肿,没有人同时报告坐骨神经痛和神经性跛行。我们介绍了一例60岁的女性,其症状为双侧坐骨神经痛和神经源性跛行。腰椎的磁共振成像显示与L4/5水平的小关节相关的双侧病变,由于这些双侧病变在同一水平上的侵蚀,导致双侧外侧隐窝狭窄和中央管狭窄。她接受了L4/5级的选择性中央管减压术,并双侧切除了小关节囊肿,并进行了外侧隐窝减压,这导致了神经根和跛行症状的良好缓解。
    Symptomatic bilateral juxtafacet ganglion cysts are relatively uncommon in the degenerated spine. The literature describes 16 cases of bilateral ganglion or synovial cysts, none reported sciatica and neurogenic claudication simultaneously. We present a case of a 60-year-old woman who presented with symptoms of bilateral sciatica and neurogenic claudication. Magnetic resonance imaging of the lumbar spine revealed bilateral lesions related to the facet joints at the L4/5 level, causing bilateral lateral recess stenosis and narrowing of the central canal due to encroachment of these bilateral lesions at the same level. She underwent an elective central canal decompression of the L4/5 level and excision of the facet cysts bilaterally with lateral recess decompression, which resulted in good relief of both the radicular and claudication symptoms.
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  • 文章类型: Journal Article
    OBJECTIVE: To describe the clinical findings, imaging features, underlying conditions, treatment, and progression of dogs presented between 2010 and 2019 with neurogenic keratoconjunctivitis sicca (NKCS).
    METHODS: Dogs diagnosed with NKCS were searched in the clinical database. Inclusion criteria were STT-1 readings <15 mm/min, clinical signs of KCS with concurrent ipsilateral xeromycteria.
    RESULTS: Thirty-four cases were identified. Mean age at presentation was 8.2 years, median 8.9 years (0.3-14.7). Twenty dogs were male, and 14 dogs were female. Concurrent neurological deficits included facial neuropathy (n = 13, 38%), peripheral vestibular syndrome (n = 10, 29%), and Horner\'s syndrome (n = 5, 15%). Advanced imaging was acquired in 53% of cases (n = 18). Etiologies included idiopathic (n = 18, 53%), endocrinopathy (n = 6, 18%), otitis interna (n = 4, 12%), head trauma (n = 3, 9%), iatrogenic (post-TECA-LBO, n = 1, 3%), brainstem mass (n = 1, 3%), and an area of inflammation in the pterygopalatine fossa (n = 1, 3%). Treatment for NKCS was initiated in most cases (n = 30, 88%) including: oral pilocarpine 2% and lacrimostimulant (n = 19), oral pilocarpine 2% only (n = 3), or lacrimostimulant only (n = 8). A mean time follow-up of 3.7 months, median 3 months (1-14) was available in 23 cases (68%). Eleven cases with follow-up were responsive (48%) with resolution of the clinical signs in a median time 4 months (1-10), and all of them were treated with oral pilocarpine (±lacrimostimulant).
    CONCLUSIONS: Most cases presented as idiopathic NKCS; in others, an underlying cause of facial neuropathy was identified. All responsive cases were treated with oral pilocarpine 2%.
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  • 文章类型: Case Reports
    BACKGROUND: Neurogenic tumors account for about ten percent of all tumors of childhood, and benign tumor originating from Schwann cells is rare in peripheral nerves. Schwannoma of the tongue is quite rare in children.
    METHODS: We present the case of an 8-year-old male with schwannoma in the anterolateral tongue. The mass was slow-growing for one year with no pain and discomfort. He underwent transoral mass excision under general anesthesia. Gross examination revealed a smooth surfaced, 17 mm × 14 mm × 7 mm sized, encapsulated nodule with a clear resection margin. Schwannoma of the tongue was confirmed by the pathological exam. He reported no motor or sensory change, such as dysgeusia or paresthesia, or phonation difficulty during postoperative 12 mo follow-up.
    CONCLUSIONS: Schwannoma of the tongue is a rare benign neoplasm in childhood. If a painless firm mass is encountered in the tongue of a child, solid tumors like schwannoma should be considered in the differential diagnosis.
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  • 文章类型: Case Reports
    有症状的双侧并列神经节囊肿在退化的脊柱中相对少见。文献描述了16例双侧神经节或滑膜囊肿,没有人同时报告坐骨神经痛和神经性跛行。我们介绍了一例60岁的女性,其症状为双侧坐骨神经痛和神经源性跛行。腰椎的磁共振成像显示与L4/5水平的小关节相关的双侧病变,由于这些双侧病变在同一水平上的侵蚀,导致双侧外侧隐窝狭窄和中央管狭窄。她接受了L4/5级的选择性中央管减压术,并双侧切除了小关节囊肿,并进行了外侧隐窝减压,这导致了神经根和跛行症状的良好缓解。
    Symptomatic bilateral juxtafacet ganglion cysts are relatively uncommon in the degenerated spine. The literature describes 16 cases of bilateral ganglion or synovial cysts, none reported sciatica and neurogenic claudication simultaneously. We present a case of a 60-year-old woman who presented with symptoms of bilateral sciatica and neurogenic claudication. Magnetic resonance imaging of the lumbar spine revealed bilateral lesions related to the facet joints at the L4/5 level, causing bilateral lateral recess stenosis and narrowing of the central canal due to encroachment of these bilateral lesions at the same level. She underwent an elective central canal decompression of the L4/5 level and excision of the facet cysts bilaterally with lateral recess decompression, which resulted in good relief of both the radicular and claudication symptoms.
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